Clinical trials: Periodontitis, Chronic
Polycystic Ovary Syndrome, Chronic Periodontitis
Chronic Periodontitis and Polycystic Ovary Syndrome
Background: The aim of this study was to investigate the levels of malondialdehyde (MDA), total antioxidant status (TAS), 8-hydroxy-2´- deoxyguanosine (8-OHdG) in blood serum and saliva samples in female patients with chronic…
- Trial name
- NCT02954120
- Testing
- no intervention provided
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Periodontitis, Adult, Furcation Defects
A Chitosan Brush and Enamel Matrix Derivative for Non-surgical Treatment of Furcations
Patients diagnosed with stage III or IV periodontitis who exhibit mandibular first or second molars with Class II, Subclass A, or B buccal and/or lingual mandibular furcation defects (horizontal probing depth of ≥ 3 mm ) will be…
- Conditions
- Periodontitis, Adult, Furcation Defects, Furcation of Root of Tooth, Periodontitis Complex
- Trial name
- NCT06684769
- Testing
- Emdogain® FL, Labrida BioClean®
- Where
- Latvia
- Volunteers
- 40 people
- Sponsor
- Riga Stradins University
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Chronic Periodontitis, Diabetes Mellitus, Type 2
Effectiveness of Non-surgical Periodontal Treatment on HbA1c Levels in a Patient With Type 2 Diabetes Mellitus
This study evaluates the effectiveness of an intervention, non-surgical periodontal treatment (SPR), in patients with poorly controlled type 2 diabetes mellitus and moderate-severe periodontal disease aimed at reducing HbA1c…
- Trial name
- NCT04051866
- Testing
- Non-surgical periodontal treatment: Scaling and root planing (SRP), Oral hygiene instructions
- Where
- Spain
- Sponsor
- Gerencia de Atención Primaria, Madrid
Chronic Periodontitis
Effect of Nonsurgical Periodontal Therapy Verses Oral Hygiene Instructions on Patients With Chronic Periodontitis
Periodontitis, a bacterial dental biofilm based infectious disease, is a chronic inflammatory disease of the periodontium which results in irreversible destruction of supporting structures of the teeth such as periodontal…
- Trial name
- NCT02208739
- Testing
- Nonsurgical periodontal therapy, Oral hygiene instructions
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- University of Malaya
Periodontal Diseases, Periodontitis
HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy
This observational clinical study aims to investigate the relationship between the HALP score (Hemoglobin × Albumin × Lymphocyte / Platelet), several blood-based inflammatory indices (including NLR, PLR, LMR, and SII), and…
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis; Chronic
- Trial name
- NCT07312045
- Testing
- Non-surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Okumuş
Chronic Kidney Diseases, Periapical Lesions
Association of Apical Periodontitis With Chronic Kidney Disease
This investigation is aimed to assess the prevalence and severity of apical periodontitis (AP) in different stages of CKD patients and its impact on the systemic (nutritional and inflammatory) markers was compared to healthy…
- Trial name
- NCT05818657
- Testing
- levels of CKD markers, Oral health status, apical periodontitis, systemic inflammatory marker, Oral health status, apical periodontitis
- Where
- India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Periodontitis
To Study the Healing Effect of 0.25% Lemongrass Oil Mouthwash on Chronic Periodontitis Patients.
Periodontitis is the inflammation of the tissues supporting the teeth. Lemongrass (Cymbopogon Citratus) oil mouthwash can be used with subgingival scaling in the treatment of periodontal diseases.
- Trial name
- NCT05502627
- Testing
- 0.25% lemon grass oil mouthwash
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Medical Institute, Lahore
Alveolar Bone Loss Associated Chronic Periodontitis
Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis
This open label, randomized controlled clinical trial study will be conducted after obtaining ERC approval of Bahria University Health Sciences. Written informed consent will be taken from all study participants.
- Trial name
- NCT06856369
- Testing
- Platelet rich fibrin, Metformin hydrochloride powder, alendronate sodium powder
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bahria University
Bovine Bone, Concentrated Growth Factor
Bovine Bone With or Without Concentrated Growth Factor in the Treatment of Chronic Periodontitis
The aim of this study is to compare bovine bone with or without concentrated growth factor in the treatment of chronic periodontitis.
- Conditions
- Bovine Bone, Concentrated Growth Factor, Chronic Periodontitis
- Trial name
- NCT07108790
- Testing
- Concentrated growth factors, collagen membrane and xenograft bone graft, Collagen membrane and xenograft bone graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Periodontal Diseases, Periodontitis
Interaction Between Immune Cells and Bacteria Associated With Periodontitis
This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease.
- Conditions
- Periodontal Diseases, Periodontitis, Aggressive Periodontitis, Immunologic Disease
- Trial name
- NCT03225950
- Testing
- In vitro stimulation of blood with periodontitis-associated- and control bacteria, Anti-CCP- and anti-P.g.-antibodies titers, Analysis of selected single nucleotide polymorphisms (SNPs)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Periodontitis, Adult, Periodontitis
Evaluation of Masticatory Performance in Patients With Periodontitis
The objective of this observational study is to assess the correlation between the severity of periodontal involvement and masticatory performance in patients with periodontitis.
- Conditions
- Periodontitis, Adult, Periodontitis, Oral Disease
- Trial name
- PAROCHEW (NCT07665489)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Periodontitis
Evaluation of Local Delivery of Aloe Vera Gel as an Adjunct to Non-surgical Treatment in Patients With Chronic Periodontitis
Aim of the current study was to evaluate the effect of Aloe vera gel as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis.
- Trial name
- NCT04615585
- Testing
- Aloe vera after SRP, Scaling and root planing (SRP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nourhan M.Aly
Diabetes Mellitus, Chronic Periodontitis
Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes Mellitus
A study on the effect of locally delivered aloe vera gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis patients with controlled type II diabetes mellitus.The evaluation of Plaque Index…
- Trial name
- NCT02437747
- Testing
- SRP + Aloe, SRP
- Volunteers
- 15 people
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Periodontitis, Adult, Periodontitis
Evaluation of Changes in Oral Health-related Quality of Life During the Treatment of Periodontitis.
Periodontitis is a chronic inflammatory disease affecting the supporting tissues of the teeth and may negatively affect patients' oral health-related quality of life.
- Conditions
- Periodontitis, Adult, Periodontitis, Oral Disease, Quality of Life
- Trial name
- PAROQoL (NCT07868042)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Parodontitis Aggressive, Parodontitis Chronic
Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Severe Periodontitis
The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses.
- Trial name
- NCT01246648
- Testing
- Biopsy
- Where
- France
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Apical Periodontitis
Single Versus Multiple Visits Regenerative Endodontics in Mature Teeth
The goal of this clinical trial is to learn whether regenerative endodontic treatment (RET) should be performed in one visit or two visits in people with mature permanent teeth with chronic apical periodontitis.
- Trial name
- NCT07480226
- Testing
- Single-Visit Regenerative Endodontic Treatment, Multiple-Visit Regenerative Endodontic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Marmara University
Periodontitis, Adult, Prediabetes / Type 2 Diabetes
HbA1c Screening in Dental Care and Primary Care Referral in Patients With Advanced Periodontitis
This study will evaluate whether HbA1c screening can be performed in dental care to detect elevated blood glucose in patients with advanced periodontitis and support referral to primary care.
- Trial name
- DENT-PC (NCT07688278)
- Testing
- Point-of-care HbA1c screening, Conditional standardized primary care referral
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Region Skane
Periodontitis Chronic Generalized Severe, Intrabony Periodontal Defect
Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
Several minimal invasive techniques have been proposed since the last decade aiming to enhance and provide adequate environment for periodontal regeneration.
- Trial name
- NCT04444063
- Testing
- Non-Incised Papilla Surgical Approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University