Clinical trials: Periodontitis
- Condition Periodontitis
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Periodontitis
Emdogain Minimally Invasive Surgical Technique
The aim of this controlled study is to assess the clinical outcomes and patient reported outcomes of using minimally invasive surgical procedure with Straumann Emdogain as an adjunct (test treatment) or without Straumann Emdogain…
- Trial name
- NCT02551770
- Testing
- Scaling and root planing, Scaling and root planing without Emdogain, Emdogain application
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Periodontal Diseases
Treatment of Advanced Periodontitis Using an Oscillating Chitosan Device Versus Regular Curettes Alone
40 patients diagnosed with localised periodontitis will be included at each center, 20 patients will be treated with the control treatment, 20 patients will be treated by test treatment.
- Trial name
- NCT04173156
- Testing
- Labrida Bioclean, Gracey Periodontal curettes
- Where
- 3 sites in Norway, Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Labrida AS
Periodontitis, Dental Plaque
At-Home Care for Subjects With Periodontitis
The effect of use of powered toothbrushing in patients exhibiting periodontal inflammation has been observed repeatedly in clinical studies conducted over a 20+ year period.
- Trial name
- NCT04254770
- Testing
- ADA approved Manual Toothbrush, Marketed Power Toothbrush
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Apical Periodontitis
A Study to Compare Various Root Canal Cleaning Devices Based on Cavitation,Ultrasonic and Conventional Methods.
The goal of this clinical trial is to compare the effectiveness of various root canal cleaning devices based on the principle of cavitation, ultrasonics, and conventional methods in a normal healthy adult population aged between…
- Trial name
- NCT06005545
- Testing
- Passive Ultrasonic Irrigation (PUI) group, Endoclean (EC) group, Conventional group
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Periodontitis
Regular Home Use of Dual-light Photodynamic Therapy in the Management of Chronic Periodontitis
The study is a single site, randomized clinical trial designed to determine the efficacy of the Lumoral treatment in periodontitis patients.
- Trial name
- HOPE-CP (NCT05278416)
- Testing
- Lumoral treatment -device and Lumorinse tablets
- Where
- Finland
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Gingival Diseases
Collection of Gingival Crevicular Fluid From Periodontitis Patients
To collect GCF (gingival crevicular fluid) samples from diseased patients suffering only from gingivitis and/or periodontitis.
- Trial name
- NCT00763048
- Testing
- Fluoride, Fluoride, triclosan
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Diabetes Type 2, Periodontitis
Exploratory Study of Iocide Oral Rinse in a Diabetic Population
The goals of this exploratory study are to 1)examine an investigational oral rinse as an adjunctive agent to scaling and root planing in treating chronic periodontitis in a periodontitis-susceptible diabetes population, and 2)…
- Trial name
- Diabetes (NCT00801164)
- Testing
- Frio Mouth Rinse
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biomedical Development Corporation
Periodontitis
A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)
This clinical multi-center, controlled, study will be carried out in volunteers with every 3- to 6-months professional tooth cleaning during their non-treatment period between 2 re-calls of a supportive periodontitis therapy…
- Trial name
- NCT07397312
- Testing
- Toothpaste
- Where
- 5 sites in Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Periotrap Pharmaceuticals GmbH
Periodontitis
A Safety/Tolerability and Pharmakokinetic Study of Sargramostim Administrated in the Gingiva
This exploratory study is the first study in a clinical program where the overall objective is to develop a novel pharmaceutical therapy comprising local administration of GM-CSF for the treatment of periodontitis.
- Trial name
- NCT00689143
- Testing
- sargramostim
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Innoventus Project AB
Periodontal Disease
Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study.
- Trial name
- NCT06582056
- Testing
- Investigational Procedure
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Periodontitis, Periodontal Pocket
Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel
In the here suggested study, the aim is to test non-surgical treatment of advanced periodontal disease with a chitosan brush with or without chitosan gel in patients with advanced periodontal disease having responded poorly to a…
- Conditions
- Periodontitis, Periodontal Pocket, Periodontal Diseases, Periodontal Inflammation
- Trial name
- Chitosangel (NCT05773911)
- Testing
- 4% chitosan gel (pH 3.48)., Reciprocal Chitosan brush
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Caspar Wohlfahrt
Chronic Periodontitis
Perio. Maint. With Diode LBR
The primary aim of this pilot study is to determine whether the test methods described feasibly achieve the goal defined for a future clinical study.
- Trial name
- NCT05276817
- Testing
- Epic Diode, HP
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Biolase Inc
Periodontal Disease
Periodontal Disease Treatment of a Physically Challenged Population
Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush.
- Trial name
- PDT (NCT01718912)
- Testing
- metronidazole-nystatin oral rinse
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Oravital Inc
Periodontal Diseases
Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis
A comparison of laser (REPaiR) compared with minimally invasive surgical therapy for moderate to severe periodontal disease.
- Trial name
- NCT04169139
- Testing
- MIST (minimally invasive surgical therapy)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- McGuire Institute
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Periodontitis
A Phase I/II Study to Evaluate the Safety and Efficacy of PerioSept® as Adjunct to SRP in Subjects With Periodontitis
A Pharmacokinetic Pilot followed by a Phase I/II, Blinded, Randomized, Controlled, Parallel Arm Trial to Evaluate the Safety, Tolerability and Efficacy of PerioSept® and Scaling and Root Planing in Subjects with Periodontitis
- Trial name
- NCT02313883
- Testing
- PerioSept(r)
- Where
- 4 sites in United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Geistlich Pharma AG
Periodontitis
Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Population
Clinical research study to determine the effectiveness of a triclosan/copolymer/fluoride toothpaste in maintaining periodontal health and therefore glycaemic control in a type 2 diabetic population.
- Trial name
- NCT00762762
- Testing
- Triclosan/copolymer/fluoride, Fluoride
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis, Gingivitis
Effect of a Liquid Toothpaste on Periodontal Disease
The aim of the present clinical study is to evaluate the efficacy and safety of the novel toothpaste in patients diagnosed with gingivitis and/or periodontitis.
- Trial name
- NCT03117153
- Testing
- DA-5502 liquid toothpaste
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Dong-A Pharmaceutical