Clinical trials: Periodontitis, completed
Chronic Periodontitis, Generalized, Moderate
Er:YAG Laser Treatment of Moderate Chronic Periodontitis
The Er:YAG laser possesses specific characteristics allowing to be used in non-surgical periodontal treatment. The aim of the resent study was to evaluate the long-term clinical effectiveness of Er:YAG laser monotherapy in the…
- Trial name
- NCT05217823
- Testing
- Er:YAG laser, hand instruments
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Aggressive Periodontitis, Generalized
Subgingival Microbiota Following Mechanical Treatment and it's Effect on Peri-implant Sub-mucosa in Periodontitis Patients
The investigators planed to observe the microbiome of an aggressive periodontitis patient, during mechanical treatment, surgery(if indicated) and implant placement.
- Trial name
- NCT03090282
- Testing
- mechanical treatment(mainly scaling and root planing), periodontal surgery(if indicated), implant placement.
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Peking University
Periodontitis, Periodontal Pocket
Amoxicillin Plus Metronidazole in Periodontal Maintenance
Gum disease require a lifetime supportive periodontal care aiming at preventing additional inflammation and bone resorption. During this phase it is also relevant to keep germs under acceptable levels through proper daily hygiene…
- Trial name
- NCT05934227
- Testing
- Amoxicillin 500 milligrams capsules plus metronidazole 400 milligrams
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Periodontitis, Periodontal Diseases
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic…
- Trial name
- NCT00066066
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- The Forsyth Institute
Vitamin D Deficiency, Periodontitis
25-Hydroxyvitamin D Levels in Patients With Periodontitis (Stage III)
Periodontitis; is an inflammatory disease of tissues characterized by bone destruction around the teeth. Vitamin D plays an important role in several inflammatory diseases by promoting the expression of inflammatory cytokines…
- Trial name
- NCT05343273
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Apical Periodontitis
Effect of Different Instrumentation Technique on Endodontic Outcome
Aim: To evaluate and compare the outcome of primary endodontic treatment following use of different instrumentation techniques. Materials and methods: Study subjects were recruited from the pool of patients referred for the…
- Trial name
- NCT03278054
- Testing
- Root Canal Treatment with hand instruments, Root canal treatment with Protaper instruments, Root canal treatment with hybrid instrumentation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Periodontitis
Autologous Alveolar Bone Marrow Mesenchymal Stem Cells for the Reconstruction of Infrabony Periodontal Defects
Systemically healthy periodontitis patients are recruited from new referrals to the Department of Periodontology and Biology of Implants, AUTh.
- Trial name
- PerioRegen (NCT02449005)
- Testing
- BM-MSCs/fibrin glue/collagen fleece, Fibrin glue/collagen fleece, Open flap debridement
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Periapical Periodontitis, Root Canal Infection
The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
This study evaluates postoperative pain and radiographic healing of asymptomatic posterior teeth with chronic apical periodontitis following root-canal treatment performed using EndoActivator for irrigation activation.
- Trial name
- NCT06339905
- Testing
- Sonic Activation with EndoActivator, Control Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Periodontal Diseases
Serum A.Actinomycetemcomitans Antibodies and Periodontitis
The aim of this study was to analyze the association between serum A.actinomycetemcomitans antibodies in patients with periodontitis.
- Trial name
- NCT04417322
- Testing
- observation of serum A.actinomycetemcomitans levels
- Where
- Italy
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of Messina
Apical Periodontitis
Assessment of Different Disinfection Protocols on Regenerative Potential of Mature Teeth
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT05557994
- Testing
- Method
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Periodontitis
Effect of Omega 3 as an Immunomodulator Adjunct to Periodontal Debridement
This study evaluates the effect of the systemic administration of Omega 3 as a therapy associated with non-surgical periodontal treatment, in the clinical and microbiological variables of patients with Moderate Periodontitis with…
- Trial name
- NCT04389931
- Testing
- Lactose tab, Omega 3
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Diabetes Mellitus, Periodontal Diseases
Effects of Omega-3 as an Adjunct to Non-Surgical Periodontal Therapy on Chemerin Level in Periodontitis Patients With Diabetes: A Randomized Clinical Trial
Patient grouping Group 1 (Type 2 Diabetes Mellitus patients with CPD + SRP and Omega-3) Group 2 (Type 2 Diabetes Mellitus patients with CPD + SRP) different clinical parameters were recorded ; plaque index (PI), gingival index…
- Trial name
- NCT06463535
- Testing
- Omega 3, SRP alone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- British University In Egypt
Post Operative Pain
Postoperative Pain After Using Different Single-File Glide Path Systems
This study aimed to evaluate postoperative pain intensity after glide-path preparation with the ProGlider (PG) and WaveOne Gold Glider (WOGG) systems in asymptomatic teeth with necrotic pulp and periapical lesions.Maxillary and…
- Trial name
- NCT05955742
- Testing
- Control, ProGlider, WaveOne Gold Glider
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Periodontitis
Effects of Low-Dose Doxycycline on Oral Bone Loss
The primary purpose of this clinical trial is to determine whether low-dose doxycycline can reduce alveolar bone density loss in postmenopausal osteopenic women with periodontitis and not on hormone replacement therapy (i.e.…
- Trial name
- NCT00066027
- Testing
- 20 mg doxycycline hyclate
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Nebraska
Type 2 Diabetes Mellitus (T2DM), Periodontal Disease
Serum Chromium, Nickel, and Magnesium in Type 2 Diabetic Periodontitis
Periodontitis is a chronic immunoinflammatory disease that has been increasingly associated with systemic conditions, particularly type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07327086
- Testing
- No intervention (Observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Chronic Periodontitis
Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony Defects
A clinical and radiographic evaluation of Nano-crystalline hydroxyapatite silica gel in comparison with open flap debridement for management of periodontal intrabony defects.
- Trial name
- NCT02507596
- Testing
- Nano-crystalline hydroxyapatite silica gel, open flap debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Effects of Periodontal Therapy on Markers of Acute Phase Response, Oxidative Stress
This study began enrollment in 2003 with final report completed in October of 2015. This submission is being provided to acquire an NCT number.
- Trial name
- BCU2 (NCT03375372)
- Testing
- Scaling and Root Planing (S&RP)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Periodontitis
The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
The purpose of this study is to determine the effect of the placement of a PerioChip Plus (flurbiprofen/chlorhexidine - FBP/CHX) formulation versus PerioChip (chlorhexidine) formulation versus Flurbiprofen Chip formulation versus…
- Trial name
- NCT00425451
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Thyroid Diseases, Chronic Periodontitis
Thyroid Disease and Chronic Periodontitis
Currently, the investigators are unaware of any previous studies that have analyzed the relationship between the prevalence of thyroid disease and chronic periodontitis among adults utilizing a retrospective, cross-sectional…
- Trial name
- NCT03369405
- Testing
- NO intervention, patient records review only
- Where
- United States
- Volunteers
- 4,965 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Chronic Periodontitis
Evaluation of SilOss® in Periodontal Surgery
Siloss® (Azurebio, Madrid, Spain) is a synthetic and inorganic bone graft material and is composed of a dicalcium phosphate anhydrous (monetite), hydroxyapatite (HA), and amorphous silica and trace amounts of zinc.
- Trial name
- NCT02639572
- Testing
- Siloss® bone graft, Hydroxyapatitie Bone graft
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences