Clinical trials: Perioperative/Postoperative Complications
Multiple Trauma, Shock
Clinical Investigation of Wireless Transmission of Invasive Blood Pressure Signal
The purpose of this study is to determine whether wireless transmission of invasive arterial blood pressure signal (by HMW 10 Wireless System) from patient to patient's bedside monitor is feasible, safe and as accurate as…
- Conditions
- Multiple Trauma, Shock, Atrial Fibrillation, Perioperative/Postoperative Complications
- Trial name
- NCT01373996
- Testing
- Wireless invasive blood pressure monitoring (Hybymed® Wireless IBPM System)
- Volunteers
- 12 people
- Sponsor
- University Medical Centre Ljubljana
Postoperative Pain, Pain Assessment
Establishment and Validation of Early-warning Model of Perioperative Pain for the Elders
This study will collect perioperative pain-related data of elderly patients in multi-centers. Analyzing these collected data to find the high-risk factors of postoperative pain in elderly patients and to establish an…
- Conditions
- Postoperative Pain, Pain Assessment, Elderly, Model
- Trial name
- NCT04228705
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Peking University People's Hospital
Colorectal Cancer, Postoperative Complications
Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery
This study evaluates the usefulness of bioelectrical impedance analysis (BIA) for perioperative fluid evaluation and prediction of postoperative complications in oncological patients undergoing colorectal surgery.
- Conditions
- Colorectal Cancer, Postoperative Complications, Fluid Imbalance
- Trial name
- NCT07404527
- Testing
- Bioelectrical Impedance Analysis
- Where
- Slovenia
- Volunteers
- 85 people
- Sponsor
- Institute of Oncology Ljubljana
Postoperative Nausea and Vomiting
PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.
- Trial name
- NCT06241547
- Testing
- electrical stimualtion via EmeTerm bracelet, antimetic drugs（ dexamethasone，ondansetron）
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Ultrasonography, Postoperative Complications
Use of Point-of-care Lung Ultrasound Before and After Surgery Trying to Predict Post-operative Pulmonary Complications
Patients undergoing surgery inside their abdomen, with no serious heart or lung diseases, will have a lung ultrasound exam before and after surgery.
- Conditions
- Ultrasonography, Postoperative Complications, Anesthesia, Surgery-Complications
- Trial name
- NCT05502926
- Testing
- lung ultrasound score
- Where
- Israel
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Moshe Rucham MD
Carotid Stenosis, Ischemia Reperfusion Injury
Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy
The aim was the comparison of the perioperative time courses of matrix metalloproteinase-9 (MMP-9) and its inhibitor (TIMP-1) during elective carotid artery stenting (CAS).
- Trial name
- NCT03410576
- Testing
- Carotid artery stenting, Carotid endarterectomy
- Where
- Hungary
- Volunteers
- 25 people
- Sponsor
- University of Pecs
Postoperative Delirium, Cerebral Oxygen Saturation
Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation
This study compares the effects of ibuprofen administered during surgery and within the first 24 hours after surgery, versus no ibuprofen, on cerebral oxygenation, postoperative changes in consciousness (postoperative delirium…
- Conditions
- Postoperative Delirium, Cerebral Oxygen Saturation, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- NCT07399184
- Testing
- ibuprofen
- Volunteers
- 54 people
- Sponsor
- Ondokuz Mayıs University
Perforated Peptic Ulcer, Fast Track Surgery
Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation.
- Conditions
- Perforated Peptic Ulcer, Fast Track Surgery, Perforated Bowel, Post-Op Complication
- Trial name
- TUBELESS (NCT05368233)
- Testing
- ERAS protocol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Bariatric Surgery, Postoperative Nausea and Vomiting
Low-Volume Oral Carbohydrate Feeding in Bariatric Surgery: Effects on PONV and Recovery
This randomized controlled trial aims to evaluate the effects of preoperative oral administration of 200 ml 12.5% carbohydrate solution on postoperative nausea, vomiting, and recovery in bariatric surgery patients.
- Trial name
- NCT07018440
- Testing
- Low-Volume Oral Carbohydrate Loading (200 mL of 12.5% solution)
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Marmara University
Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer
Effects of SPSIP Block on Perioperative Inflammation and TLR4 in Breast Cancer Surgery
This study will investigate whether the serratus posterior superior intercostal plane (SPSIP) block improves postoperative recovery after breast cancer surgery. Participants will be randomly assigned to one of two groups.
- Conditions
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer, Toll-Like Receptors
- Trial name
- SPSIP-TLR4 (NCT07843212)
- Testing
- Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mucahide Emine Fidancı Kuas
Perioperative Care, Colorectal Surgery
Postopoperarive Outcomes After Colorectal Surgery in Europe (euroPOWER)
Methods 30 days European Multicentre observational cohort study of postoperative complications following elective colorectal surgery within any compliance of an ERAS protocol (including patients with 0 compliance) in a…
- Conditions
- Perioperative Care, Colorectal Surgery, Postoperative Complications
- Trial name
- EuroPOWER (NCT03814681)
- Testing
- Colorectal Surgery
- Where
- Spain
- Volunteers
- 8,000 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
S-ketamine, Esketamine
Safety and Efficacy Evaluation of S (+) - Ketamine in Children
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in children in perioperative settings.
- Conditions
- S-ketamine, Esketamine, Acute Pain, Postoperative Pain
- Trial name
- NCT04834427
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Post-operative Hemorrhage
Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy
Tonsillectomy (removal of the tonsils) is a very common surgery in children. Bleeding after tonsillectomy is one of the risks of this surgery and can be more dangerous in children since they have less blood volume than adults.
- Trial name
- NCT01415583
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Malignant Mesothelioma, Perioperative/Postoperative Complications
Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known if radiation therapy is effective in preventing metastatic cancer following surgery.
- Trial name
- NCT00006231
- Testing
- quality-of-life assessment, standard follow-up care, radiation therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Glasgow
Surgery
Epidemiology of Perioperative Care in Sweden
The Epidemiology of Perioperative Care in Sweden (EPeCS) study is a registry-based, retrospective extensive analysis of the whole adult (≥18 years) surgical population in Sweden during six full years, 1 January 2015 - 31 December…
- Trial name
- EPeCS (NCT05560815)
- Testing
- Any surgical procedure
- Where
- Sweden
- Volunteers
- 1,500,000 people
- Sponsor
- Linkoeping University
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Chronic Postoperative Pain, Headache
Effects of Perioperative Pregabalin for Post-Craniotomy Pain
Objective: To compare the incidence of chronic pain at 3 months among adults undergoing craniotomy between those received two different doses of pregabalin and those receiving placebo.
- Trial name
- NCT01591980
- Testing
- Pregabalin
- Where
- Canada
- Sponsor
- Unity Health Toronto
Chronic Sinusitis, Postoperative Pain
Opioid-Free Anesthesia in FESS: A Prospective ERAS Study
1. Information for Patients and Families What is this study about? When patients undergo functional endoscopic sinus surgery (FESS), strong pain relievers called opioids are traditionally used during anesthesia.
- Conditions
- Chronic Sinusitis, Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Surgical Field Visibility
- Trial name
- OFA-FESS (NCT07812389)
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Filiz Kaya