Clinical trials: Perioperative/Postoperative Complications
Carcinoma, Non-Small-Cell Lung, Surgery--Complications
Dexamethasone, Flurbiprofen Axetil and Delirium After Lung Cancer Surgery
Delirium is a common complication in elderly patients after surgery. And its occurrence is associated with worse outcomes. The causes of delirium are multifactorial but may include pain, stress response and inflammation.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Surgery--Complications, Dexamethasone, Flubiprofen Axetil
- Trial name
- NCT03200600
- Testing
- Dexamethasone, Normal saline, Flurbiprofen axetil
- Where
- 2 sites in China
- Volunteers
- 126 people
- Sponsor
- Peking University First Hospital
Postoperative Complications, Randomized
Smoking Cessation and Postoperative Complications
The primary aim of this study is to evaluate the effect of preoperative smoking cessation on postoperative complications among patients undergoing surgery.
- Conditions
- Postoperative Complications, Randomized, Prevention, Smoking Cessation
- Trial name
- NCT00533000
- Testing
- Smoking cessation
- Volunteers
- 584 people
- Sponsor
- Karolinska Institutet
Nausea and Vomiting, Postoperative
Supplemental Perioperative Intravenous Crystalloids for Postoperative Nausea and Vomiting in Children Undergoing Oncological Surgery
Postoperative nausea and vomiting (PONV) is a common complication in the paediatric population and is a source of significant morbidity.
- Trial name
- NCT05658406
- Testing
- Ringer's Lactate, normal Saline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Postoperative Complications
Personalized Hemodynamic Therapy in Patients Undergoing High-risk Surgery
The purpose of this study is to evaluate the effectiveness of using the personal preoperatively assessed cardiac output in high-risk patients to guide perioperative administration of fluids and vasoactive drugs on predefined…
- Trial name
- TAPIR (NCT02834377)
- Testing
- Treatment algorithm targeting individual cardiac output
- Where
- Germany
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypotension, Head and Neck Cancer
The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.
The aim of the current study is to evaluate the effects of the Hypotension Prediction Index (HPI) on the degree of intraoperative hypotension in patients undergoing free flap surgery.
- Conditions
- Hypotension, Head and Neck Cancer, Perioperative Complication, Postoperative Complications
- Trial name
- NCT05738603
- Testing
- Hypotension Prediction Index
- Where
- Poland
- Volunteers
- 206 people
- Sponsor
- Jakub Szrama
General Anesthesia, Postoperative Complications
Muscle Relax Affects Outcomes of Robotic Surgery
During robotic laparoscopic surgery, a high intraperitoneal pressure may result in high airway pressure and inadequate perfusion of the abdominal organs, and as a result the postoperative outcomes.
- Trial name
- MORE (NCT03726372)
- Testing
- Rocuronium, continuous infusion, intermittent injection
- Volunteers
- 192 people
- Sponsor
- Air Force Military Medical University, China
Methadone, Pain, Post Operative
Perioperative Methadone in Hip Fracture Patients
Postoperative analgesic treatment needs to be improved. Numerous studies suggest that a single dose of Methadone given during surgery significantly ameliorates postoperative pain and reduces postoperative opioid consumption.
- Conditions
- Methadone, Pain, Post Operative, Pain, Postoperative, Analgesics, Opioid
- Trial name
- NCT05581901
- Testing
- Methadone (Dose1), Methadone (Dose 2), Methadone (Dose 3)
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Postoperative Pain, Postoperative Nausea and Vomiting
High-Dose Steroid for Knee Arthroplasty
The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Kneesurgery with Arthroplasty and the effect on postoperative pain and postoperative…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Knee Osteoarthritis, Perioperative/Postoperative Complications
- Trial name
- NCT03758170
- Testing
- Dexamethasone
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago