Clinical trials: Perioperative Anxiety
Surgery in Children
The Effect of Informative Animated Videos Watched Before Surgery on Anxiety and Fear in Children and Their Mothers
It is important to prepare children and their mothers psychologically for surgery. There are many initiatives to achieve this psychological preparation, including interactive educational booklets for children and their families…
- Trial name
- NCT07131982
- Testing
- Informative Animated Video to be Viewed with Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Analgesia, Lung Cancer
Perioperative Music Therapy Plus Oxycodone in Perioperative Management of Lung Surgery
To explore the feasibility and effectiveness of Perioperative Music Therapy Plus Oxycodone in pain management after thoracic surgery, patients will be randomly assigned into two groups.
- Trial name
- NCT05981924
- Testing
- Perioperative Music Therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Hao Long
Heart Rate Variability, STAI
Perioperative Changes of Heart Rate Variability Related to Anxiety and Depressiveness in Patients Undergoing General Anesthesia
Preoperative anxiety can be detected via structured and standardised screening by the State - Trait Anxiety Inventory (STAI) and Self rating Depression Scale (SDS) questionnaire.
- Conditions
- Heart Rate Variability, STAI, SDS, General Anesthesia
- Trial name
- NCT02011074
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Sedation for Patients Undergoing Peribulbar Block
A Comparative Study of Oral Gabapentin, Oral Alprazolam and Intravenous Dexmedetomidine on Perioperative Anxiety and Pain During Posterior Segment Eye Surgery Under Peribulbar Block : a Randomized, Double-blind Study.
We hypothesized that gabapentin when given orally as a premedication in patients who perform posterior segment eye surgery under peribulbar block would provide adequate anxiolysis and arousable sedation as alprazolam and…
- Trial name
- NCT04658732
- Testing
- Administration of Alprazolam , Gabapentin , Dexmedetomidine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ehab Tarek Fahmy
Psycho-educational, Anxiety
The Effect of Bibliotherapy Administered During the Preoperative Period on Vital Signs, Anxiety, and Coping With Illness in Adolescent Patients
This study aimed to evaluate the effects of bibliotherapy administered to adolescent patients in the preoperative period on vital signs, anxiety levels, and coping attitudes using a pretest-posttest controlled experimental…
- Conditions
- Psycho-educational, Anxiety, Illness, Critical
- Trial name
- Bibliotherapy (NCT07126054)
- Testing
- bibliotherapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Medipol University Hospital
Depression, Anxiety, Cardiac Surgery
Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery
A multicenter, randomized controlled, blinded prospective study to investigate the effects of esketamine on perioperative anxiety and depression in patients undergoing cardiac valve surgery.
- Conditions
- Depression, Anxiety, Cardiac Surgery, S-ketamine
- Trial name
- NCT06608030
- Testing
- Esketamine, normal saline
- Where
- 2 sites in China
- Volunteers
- 142 people
- Sponsor
- Chinese PLA General Hospital
Pain, Post Operative, Anxiety
Music Therapy in the Treatment of Perioperative Anxiety and Pain
A large number of adults who undergo surgery experience perioperative anxiety and pain. The current recommended approach to perioperative pain management is a multimodal approach including opioids.
- Conditions
- Pain, Post Operative, Anxiety, Opioid Use
- Trial name
- NCT05263635
- Testing
- Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Vasectomy, Pain
Perioperative Virtual Reality Intervention for Pain and Anxiety During Vasectomies
The goal of this clinical trial is to learn if a virtual reality (VR) program (TRIPP) can reduce pain, anxiety, and distress in adult men (aged 18+) undergoing a vasectomy under local anesthesia.
- Conditions
- Vasectomy, Pain, Anxiety, Virtual Reality
- Trial name
- NCT07055178
- Testing
- Virtual reality (VR) guided meditation therapy, Treatment as usual
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Bronchoscopy
Individualized Data-based High Simulation of Bronchoscopy Operations in Preoperative Bronchoscopy Informed Consent
A prospective randomized controlled study was conducted to investigate whether preoperative replacement of patients based on AI training instruments could alleviate preoperative anxiety.
- Trial name
- NCT06441149
- Testing
- AI-based informed consent, Standard informed consent
- Where
- China
- Volunteers
- 122 people
- Sponsor
- China-Japan Friendship Hospital
Anxiety, Patient Compliance
The Effectiveness of NeuroBot in Alleviating Anxiety of Patients Undergoing Neurovascular Surgeries
The goal of this randomized controlled trial is to investigate the effectiveness of NeuroBot in alleviating anxiety of patients undergoing neurovascular procedures.
- Conditions
- Anxiety, Patient Compliance, Knowledge
- Trial name
- NCT07144540
- Testing
- NeuroBot, Standard Care (in control arm)
- Where
- 2 sites in Hong Kong
- Volunteers
- 146 people
- Sponsor
- Chinese University of Hong Kong
Anesthesia
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
Children undergoing general anesthesia for surgery commonly need sedative and anxiolytic premedication but little clinical evidence supports is benefit for children older than 7 years old.
- Trial name
- pediaPREM (NCT05681572)
- Testing
- Midazolam, Dexmedetomidine
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier
Virtual Reality, Total Hip Arthroplasty
Effect of Virtual Reality on Perioperative Anxiety, Stress and Pain in Total Hip Arthroplasty
The aim of this study is to evaluate Virtual reality (VR) on perioperative anxiety, pain, hemodynamics, and stress hormones in patients undergoing Total hip arthroplasty (THA).
- Conditions
- Virtual Reality, Total Hip Arthroplasty, Anxiety, Stress
- Trial name
- NCT06088069
- Testing
- Virtual reality
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Anxiety, Midazolam Overdose
Effect of Aromatherapy on Perioperative Anxiety Level in Cesarean Sections
Spinal anesthesia has been accepted as the first choice for elective cesarean section due to its easy application technique and elimination of the risks of difficult intubation and aspiration.
- Conditions
- Anxiety, Midazolam Overdose, Breast Feeding
- Trial name
- NCT05334537
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Postoperative Pain, Stress, Psychological
Effect Of Electroacupuncture With Local Anesthesia On Pain And Stress During Impacted Lower Third Molar Surgery
This randomized controlled trial investigates the effect of electroacupuncture as an adjunct to local anesthesia on perioperative pain and stress during ambulatory surgical extraction of impacted lower third molars.
- Conditions
- Postoperative Pain, Stress, Psychological, Impacted Lower Third Molar
- Trial name
- EASE (NCT07509294)
- Testing
- Electroacupuncture
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University of Zagreb
Depression, Anxiety
Effect of General and Non-general Anesthesia on Perioperative Depression or Anxiety
Perioperative depression and/or anxiety play a critical role in patient presentation, satisfaction and outcomes. The aim of this study is to assess the level of perioperative depression and/or anxiety in patients with…
- Trial name
- NCT05315648
- Testing
- anesthesia approach (general anesthesia or non-general anesthesia)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Lumbar Radiculopathy
The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy
This study aims to assess the effectiveness of perioperative pain neuroscience education (PPNE) in patients who are at risk for unfavorable outcome following surgery for lumbar radiculopathy.
- Trial name
- B²EARS (NCT05047679)
- Testing
- Perioperative Pain Neuroscience Education, Perioperative Biomedical Education
- Where
- 4 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- Vrije Universiteit Brussel
Depression, Anxiety
Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression
A Dual-Center, Randomized, Controlled, Blinded, Prospective Study on the Effects of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients with Mild-to-Severe Depression
- Conditions
- Depression, Anxiety, S-ketamine, Breast Cancer
- Trial name
- NCT07374198
- Testing
- Esketamine 0.3mg/kg, normal saline
- Volunteers
- 142 people
- Sponsor
- Chinese PLA General Hospital
Preoperative Anxiety, Maladaptive Postoperative Behavior
Effects of Virtual Reality on Perioperative Pediatric Anxiety
This study evaluates the effect of virtual reality on anxiety levels in a pediatric surgical population. Half of participants will receive standard perioperative treatment, while the other half will receive additionally a virtual…
- Conditions
- Preoperative Anxiety, Maladaptive Postoperative Behavior, Emergence Delirium
- Trial name
- VIRTUALPED (NCT04043663)
- Testing
- Virtual Reality glasses, standard perioperative care without virtual reality program
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Postoperative Pain, Adults
Safety and Efficacy Evaluation of S (+) - Ketamine in Adults
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in adults in perioperative settings.
- Conditions
- Postoperative Pain, Adults, Anesthesia
- Trial name
- NCT04837170
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Anxiety, Postoperative Pain
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
Dexmedetomidine is a drug known for its pain-relieving and restlessness-reducing effects. The purpose of this run is to use the association between this use during surgery and the attrition of post-operative pain and discomfort.
- Conditions
- Anxiety, Postoperative Pain, Bleeding
- Trial name
- NCT05986942
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Burak Omur