Clinical trials: Perioperative Fluid Management
Central Venous Pressure
Central Venous Pressure Monitoring and Prognosis of High-risk Operating Patients
While central venous pressure measurement is used to guide fluid management in high risk surgical patients during perioperative period, the relationship between the value of central venous pressure and organ dysfunction and…
- Trial name
- NCT04596332
- Testing
- no intervention measures
- Volunteers
- 196 people
- Sponsor
- Fujian Provincial Hospital
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
Thoracic Surgery With One-lung Ventilation, VExUS
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute…
- Conditions
- Thoracic Surgery With One-lung Ventilation, VExUS, Fluid Management, Acute Kidney Injury
- Trial name
- VEXUS (NCT07258875)
- Testing
- Venous Excess Ultrasound, Standard of Care (SOC)
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Crete
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Prostate Cancer, Robotic Radical Prostatectomy
Hemodynamic Monitoring-Guided Goal-Directed Fluid Therapy in Robotic Radical Prostatectomy
This prospective observational cohort study evaluated goal-directed fluid therapy guided by minimally invasive hemodynamic monitoring in adult male patients undergoing elective robotic radical prostatectomy.
- Trial name
- NCT07806539
- Testing
- LiDCO-guided goal-directed fluid therapy, Conventional fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Antalya Training and Research Hospital
Perioperative Complication
Perioperative Fluid Management According to the Preoperative and Perioperative Glucose Level
Background:Hyperglycemia and hypoglycemia both cause detrimental side effects for pediatric patients. Prolonged fasting time, age dependent physiological diffences and individual differences of patients make complicated the…
- Trial name
- NCT03955237
- Testing
- Drug: dextrose containing infusion
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Experience, Life
Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study
Has the evolving anesthetic management in major abdominal surgeries had a positive impact on patients' one-year postoperative mortality and length of hospital stay? Which of the anesthetic management parameters have influenced…
- Trial name
- NCT06002776
- Testing
- a retrospective study
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Brain Edema
Haemodynamical Optimization During Brain Surgery
The decision to give fluids perioperatively could be based on methods used to identify preload responsiveness, either invasive or noninvasive estimates of stroke volume variation during mechanical ventilation.
- Trial name
- NCT04114799
- Testing
- Hemodynamic management based on invasive fluid responsiveness parameters, Hemodynamic management based on noninvasive cardiac output and SVV measurement
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital Hradec Kralove
Biliary Atresia
A Real World Study on Clinical Efficacy of Bicarbonate Ringer's Solution in Biliary Atresia Children
In most babies with biliary atresia (BA) bile ducts on the inside and outside of the liver are affected eventually leading to a complete blockage of bile flow from the liver. This in turn causes scarring (fibrosis) in the liver.
- Trial name
- NCT04506021
- Testing
- Bicarbonate Ringer's solution, Other Crystalloid
- Volunteers
- 110 people
- Sponsor
- Tongji Hospital
Hypothermia Following Anesthesia, Intraoperative Complications
Goal-Directed Temperature Management During Prolonged Abdominal Surgery
During long operations on the abdomen, patients often get cold. Doctors call this perioperative hypothermia. Even a small drop in body temperature can cause problems, such as more bleeding, wound infection, and a longer stay in…
- Conditions
- Hypothermia Following Anesthesia, Intraoperative Complications, Body Temperature Changes, Anesthesia, General
- Trial name
- NCT07854704
- Testing
- Forced-air warming, Intravenous fluid warming, Unwarmed intravenous fluids
- Where
- Russia
- Volunteers
- 61 people
- Sponsor
- The Leningrad Regional Clinical Hospital
Patients Major Laminectomy Surgery
Evaluations of Optimizing Perioperative Fluid Management on Postoperative Pain Outcomes
Patient characteristics, duration of surgery, and infusion volumes will be compared between the groups. Oxygen transport and organ function will be compared Length of hospital stay, morbidity, postoperative pain intensity were…
- Trial name
- NCT02245581
- Testing
- SVV-guided fluid management, CVP-guided fluid management
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Bladder Cancer, Urinary Diversion
Effects of Noradrenaline Administration Combined With Restrictive Intraoperative Fluid Substitution on Perioperative Outcome in Patients Undergoing Radical Cystectomy
Perioperative fluid management in abdominal surgery is a subject of controversy and current standard fluid therapy is not evidence based. Compensating decreasing blood pressure by volume substitution is common praxis.
- Trial name
- NCT01276665
- Testing
- restrictive intraoperative fluid substitution, assessment of the pelvic venous pressure
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Volume Overload
Perioperative Fluid Therapy in Pediatric Patients Undergoing Penile Hypospadias Repair
Optimization of perioperative fluid management is important for preventing adverse events, such as hypovolemia, cardiogenic shock, volume overload, and pulmonary edema, in both adult and pediatric patients.
- Trial name
- NCT04444089
- Testing
- lung ultrasound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intraoperative Fluid Management
Advanced Monitoring to Inform and Guide Perioperative Hemodynamic Optimization 1 (AMIGO-1) Study
Serious complications occur in about 16% of major surgeries. Episode of hypotension during surgery may be a leading cause of these complications.
- Trial name
- AMIGO-1 (NCT03477617)
- Testing
- Intraoperative Hemodynamic Algorithm, Usual hemodynamic management
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Critical Illness
Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support
Background Intraoperative hypotension is a common problem that significantly contributes to perioperative mortality and morbidity.
- Trial name
- KATECHOL (NCT02414555)
- Testing
- vasopressor, fluid bolus, oesophagus doppler (CardioQ)
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Intraoperative Hypotension
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia.
- Trial name
- NCT07301307
- Testing
- Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Inotropy, Fluid Management
RESIPI for Reducing Perioperative Major Adverse Cardiac Events
This study aims to evaluate the effect of a novel hemodynamic management and monitoring strategy for reducing cardiac bio marker elevations and major adverse cardiac events.
- Conditions
- Inotropy, Fluid Management, Cardiac Event, Perioperative Cardiac Risk
- Trial name
- RESIPI (NCT03208023)
- Testing
- RESIPI Management Strategy, No intervention
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Vanderbilt University Medical Center
Fluid Retention Tissue
Comparison of Liberal and Restrictive Fluid Management on the Endothelial Glycocalyx in Radical Cystectomy
The aim of this study is to compare the effect of the liberal and restrictive fluid treatments which are routinely performed in major urological surgeries in the perioperative period on ANP release and the endothelial glycocalyx…
- Trial name
- NCT04780490
- Testing
- liberal fluid management, restrictive fluid management
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Istanbul University
Influence of Perioperative Fluid Regime on Intraocular Pressure During Laparoscopic Gynecologic Surgery
Influence of Perioperative Fluid Management on Intraocular Pressure During Hynecologic Laparoscopic Pelvic Surgery
The aim of this study was to quantify the Intraocular Pressure (IOP) changes in patients undergoing laparoscopic hysterectomy at different time points and body positions throughout the procedure, and to explore the influence of…
- Trial name
- NCT01676064
- Testing
- ringer lactate solution, restrictive fluid regime
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ziv Hospital
Major Abdominal Surgery, Perioperative Haemodynamic Monitoring
Continuous Central Venous Oxygen Saturation Assisted Intraoperative Hemodynamic Management
Patients who are scheduled for: elective oesophageal tumour resection, total gastrectomy, pancreas resection, major vascular, total cystectomy will be recruited.To investigate effects of central venous pressure (CVP) and central…
- Conditions
- Major Abdominal Surgery, Perioperative Haemodynamic Monitoring, Perioperative Fluid Management, Perioperative Vasopressor Requirement
- Trial name
- NCT02337010
- Testing
- CeVOX, CVP, Fluid bolus
- Where
- Hungary
- Volunteers
- 79 people
- Sponsor
- Domonkos Trásy