Clinical trials: Perioperative Hemodynamic
Hypotension, Hemodynamic Instability
Perioperative Hypotension in Gynaecologic Oncologic Surgery: HPI-ClearSight Versus Arterial Waveform Analysis
Background Intraoperative hypotension is associated with increased morbidity and mortality. The Hypotension Prediction Index (HPI) is an advancement of the arterial waveform analysis to predict intraoperative hypotension minutes…
- Conditions
- Hypotension, Hemodynamic Instability, Gynecologic Cancer
- Trial name
- NCT05354661
- Testing
- Hypotension Prediction Index
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiovascular Risk Factors
Echocardiography Management for Patients Requiring Care for Non-Cardiac Surgery
The growing population of institution patients with heart failure combined with the increasing number of surgical procedures performed each year supports the need for a critical analysis of how to most appropriately manage these…
- Trial name
- EGHEM (NCT01050361)
- Testing
- Transthoracic Echocardiogram (TTE)/Transesophageal Echocardiogram (TEE)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Perioperative Fluid Management, Hemodynamic Monitoring
Study Of Ultrasound Windows For Measuring Inferior Vena Cava Changes Before Cardiac Surgery
This research study will compare two ultrasound methods for assessing the inferior vena cava (IVC), a major vein that reflects intravascular fluid status and cardiac function before and after surgery.
- Conditions
- Perioperative Fluid Management, Hemodynamic Monitoring, Inferior Vena Cava Collapsibility Index, Cardiac Surgery Patients
- Trial name
- THRIVE-CARD (NCT07305051)
- Where
- Canada
- Volunteers
- 283 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hemodynamic Stability
Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb Surgery
to compare the safety and efficacy of spinal anesthesia using Hyperbaric Prilocaine 2% versus Hyperbaric Bupivacaine 0.5% for patients with peripheral vascular disease and cardiac dysfunction.
- Trial name
- NCT05877690
- Testing
- Bupivacaine 0.5% Injectable Solution, Prilocaine Hydrochloride 2% Injection
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Perioperative Early Tiredness (Acute Fatigue), Electrical Cardiometry
Perioperative Early Tiredness (Acute Fatigue) in Patients With Epithelial Ovarian Cancer
In surgical patients early risk prediction of postoperative complications and organ dysfunctions is still an important clinical challenge whereas appropriate risk predictors are still missing.
- Conditions
- Perioperative Early Tiredness (Acute Fatigue), Electrical Cardiometry, Biosignals, Mitochondrial Dysfunction
- Trial name
- PERISCOPE (NCT03131102)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Aarne Feldheiser
Kidney Transplant, Complications
PGDT in Patients Undergoing Kidney Transplant
This study is a multicentric randomized controlled trial comparing two groups of patients undergoing single or dual kidney transplantation from deceased donors.
- Trial name
- PGDT (NCT05035537)
- Testing
- PGDT
- Where
- 2 sites in Italy
- Volunteers
- 181 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hip Orthopaedic
Cohort Study of Perioperative Ultrasound and Delirium Following Hip Surgery
About this study This is a single-center prospective observational cohort study involving older adults undergoing hip surgery. The investigators will collect clinical and ultrasound-related information without changing routine…
- Trial name
- UPED (NCT07820007)
- Testing
- Peri-operative observational data collection of bedside ultrasound and hemodynamic parameters
- Where
- China
- Volunteers
- 620 people
- Sponsor
- Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Cholangiopancreatography, Endoscopic Retrograde, Endoscopic Ultrasonography
Non-invasive Monitor in Endoscopic Invasive Procedure
Investigators include the patients who need painless invasive endoscopic procedure, investigators collect the demographic data and apply the non-invasive device ICON on participants during the who procedure.
- Trial name
- NCT03292627
- Testing
- Portable Noninvasive Hemodynamic Monitor
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Analgesia, Pain, Postoperative
Effects of Intraoperative Magnesium Sulfate on Perioperative Pain Relief After Spine Surgery
The treatment of postoperative pain is increasingly based on a multimodal approach and although opioids remain the drug of choice, they are often used in combination with other analgesics (paracetamol, cyclooxygenase inhibitors…
- Conditions
- Analgesia, Pain, Postoperative, Spine Disease
- Trial name
- NCT04161729
- Testing
- Magnesium Sulfate, Isotonic saline 0.9%
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Aristotle University Of Thessaloniki
Liver Transplantation, Ischaemia Reperfusion Injury
Effect of Discarding Initial Reperfusion Blood on Hemodynamics, Liver Function, and 30-Day Outcomes in Liver Transplantation
Hepatic reperfusion during liver transplantation remains a critical phase associated with significant hemodynamic and systemic disturbances, despite advances in surgical and anesthetic management.
- Conditions
- Liver Transplantation, Ischaemia Reperfusion Injury, Perioperative Complications
- Trial name
- NCT07631689
- Testing
- Reperfusion Blood Discard, Standard Liver Transplantation
- Volunteers
- 132 people
- Sponsor
- University of Sao Paulo General Hospital
Uterine Bleeding, Uterine Neoplasms
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after…
- Conditions
- Uterine Bleeding, Uterine Neoplasms, Uterine Diseases, Uterine Fibroids
- Trial name
- NCT07046949
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA)
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Yuri Semenyuk Rivne Regional Clinical Hospital
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Erector Spina Plan Block, Opioid Consumption
Effects of Erector Spinae Plane Block on Opioid Consumption, Anesthetic Consumption and Hemodynamics in Lumbar Disc Herniation Surgeries.
Lumbar disc herniation (LDH) is an increasingly common spine disorder . In patients treated surgically, inhalation anesthesia and the use of opioids for analgesic purposes are generally the chosen anesthetic methods.
- Conditions
- Erector Spina Plan Block, Opioid Consumption, Postoperative Pain
- Trial name
- NCT06933498
- Testing
- PREOPERATIVE ESPB, INTRAOPERATIVE ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Tachycardia, Hypertension
A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial Surgery
It was hypothesized that the use of esmolol as an alternative to remifentanil with sevoflurane inhalation anesthesia during intracranial surgery, could provide better hemodynamic conditions and cause lesser side effects in the…
- Conditions
- Tachycardia, Hypertension, Myocardial Ischemia
- Trial name
- NCT01628562
- Testing
- Esmolol, Remifentanil
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Major Abdominal Surgery
Perioperative Hemodynamic Optimization Using the NICOM Device
In the last years, there is a growing interest in the improvement of prognosis and shortening of hospital length of stay in high-risk surgical patients.
- Trial name
- NCT01217151
- Testing
- Hemodynamic monitoring, Usual treatment
- Where
- 4 sites in Israel, Spain
- Volunteers
- 142 people
- Sponsor
- Hospital Universitario La Paz
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Colon Carcinima
The Application of the ELFI-TECH Monitor for Perioperative Hemodynamic Measurements
The elfitor device is a small non invasive device that uses dynamic light scattering to measure skin bloodflow, blood velocity, coagulation and hemodynamic parameters.
- Trial name
- NCT02628431
- Testing
- Elfi tech monitor
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Orthopedic Disorder, Hemodynamic Instability
Hypotension Prediction Index Based Perioperative Protocolized Hemodynamic Management in Geriatric Orthopedic Surgery
Blood pressure optimization has been considered as a crucial factor to avoid perioperative vital organ hypoperfusion, and perioperative hypotension has been addressed as a risk factor for complications and adverse clinical…
- Trial name
- NCT05274412
- Testing
- hypotension prediction index(HPI), ordinary goal-directed hemodynamic therapy
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- National Taiwan University Hospital
Emergence Agitation, Remimazolam Besylate
Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery
Emergence agitation (EA) is a transient, self-limited, non-fluctuating state of psychomotor excitement, which closely revolves around the emergence of general anesthesia.
- Conditions
- Emergence Agitation, Remimazolam Besylate, Perioperative Sedation, Laparoscopic Abdominal Surgery
- Trial name
- NCT05624424
- Testing
- Rematazolam Besylate, Propofol, Sevoflurane
- Where
- 6 sites in China
- Volunteers
- 1,317 people
- Sponsor
- Second Affiliated Hospital of Nanchang University