Clinical trials: Perioperative Medication Safety
Gastroesophageal Adenocarcinoma
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
GEMINI-PeriOp GC study will assess the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity of novel agents or novel combinations as perioperative treatment in participants with locally advanced…
- Trial name
- NCT07069712
- Testing
- Sonesitatug Vedotin, Rilvegostomig, Trastuzumab Deruxtecan (T-DXd)
- Where
- 70 sites in United States, Canada and 9 more
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time
Gastric Emptying With Metoclopramide in GLP-1 Agonist Patients Undergoing Elective Surgery
This is a multicentre, investigator-blinded, randomised controlled trial evaluating whether the use of oral metoclopramide before surgery can reduce the amount of residual gastric content in patients who are taking glucagon-like…
- Conditions
- Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time, Preoperative Risk Assessment, Obesity (Disorder)
- Trial name
- GEM-GLP1RA (NCT07100691)
- Testing
- Metoclopramide
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Critical Illness, Surgical Procedure, Unspecified
Preoperative Fasting vs. Not Fasting in Critically Ill Patients
The goal of this clinical trial is to learn if fasting or not fasting before a procedure has an effect on recovery in those who are critically ill.
- Conditions
- Critical Illness, Surgical Procedure, Unspecified, Pulmonary Aspiration, Fasting
- Trial name
- FEEDS (NCT06751043)
- Testing
- Fasting, Not fasting
- Where
- 19 sites in United States
- Volunteers
- 1,072 people
- Sponsor
- Massachusetts General Hospital
Postoperative Seizures After Brain Tumor Surgery
Levetiracetam for Seizure Prevention After Brain Tumor Surgery
This study aims to evaluate the efficacy and safety of levetiracetam for the prevention of postoperative seizures in adult patients undergoing supratentorial brain tumor surgery.
- Trial name
- PREVENT (NCT07239115)
- Testing
- Levetiracetam
- Where
- China
- Volunteers
- 558 people
- Sponsor
- Beijing Tiantan Hospital
Perioperative Medication Errors, Perioperative Adverse Medication Events
Usability of a Perioperative Medication-Related Clinical Decision Support Application
The goal of this study is to compare the usability of a novel, medication-related clinical decision support (CDS) application to the current standard medication administration and documentation workflow.
- Trial name
- NCT04988737
- Testing
- Electronic Clinical Decision Support Application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Cancer, Nonsmall Cell, Perioperative
Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy
Cough after lobectomy is common. The prevention and treatment of cough after lobectomy is not standardized. Breztri Aerosphere is often used to relieve cough.
- Conditions
- Lung Cancer, Nonsmall Cell, Perioperative, Cough, Drug Effect
- Trial name
- NCT05472350
- Testing
- Breztri Aerosphere
- Volunteers
- 128 people
- Sponsor
- Jianxing He
Perioperative Medication Safety
Perioperative Recommendations for Medication Safety
The purpose of the proposed research is to create and disseminate expert-based recommendations for perioperative medication safety that are tailored to country income level, using the World Bank's four country income groups…
- Trial name
- NCT04240301
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Karen C. Nanji,M.D.,M.P.H.
Perioperative Medication Errors, Perioperative Adverse Medication Events
RCT: The Effect of an Electronic Clinical Decision Support Application on Perioperative Medication Errors.
The purpose of this study is to assess the effect of a novel clinical decision support application on the rate of perioperative medication errors and preventable adverse medication events.
- Trial name
- NCT04342013
- Testing
- Electronic Clinical Decision Support Application
- Volunteers
- 300 people
- Sponsor
- Karen C. Nanji,M.D.,M.P.H.