Clinical trials: Perioperative Medicine
Cardiac Diseases
The Effect of Perioperative Medications on the Outcomes of Patients Undergoing Cardiac Surgery
This study will be a retrospective study. The patient data from the electronic medical records and existing database will be collected and analyzed.
- Trial name
- NCT01683448
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hypertension, Metabolic Syndrome
Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol
HASS-2 is a multi-center, cross-sectional quality improvement project: evaluating the implementation of a hypertension guideline protocol by perioperative clinicians, as a model for improving various aspects of public health.
- Conditions
- Hypertension, Metabolic Syndrome, Non-Compliance, Medication
- Trial name
- HASS-2 (NCT03921086)
- Testing
- Antihypertensive medication according to the study's algorithm
- Where
- 7 sites in South Africa
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Allergic Reaction, Hypersensitivity
Standardised Drug Provocation Testing in Perioperative Hypersensitivity
The goal of this clinical trial is to evaluate the safety and outcome of systematic drug provocation testing with anaesthetics at therapeutic doses in adult patients undergoing diagnostic work-up for perioperative…
- Conditions
- Allergic Reaction, Hypersensitivity, Perioperative Complication, Anaphylaxis
- Trial name
- NCT06065137
- Testing
- Full dose DPT with propofol, Full dose DPT with ketamine, Full dose DPT with etomidate
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Analgesia, Effect of Drug
Comparison of Perioperative Analgesia Between Intravenous Paracetamol and Fentanyl for Rigid Hysteroscopy
Objective of study: To compare the efficacy of intravenous paracetamol and fentanyl for intra-operative and post-operative pain relief in patients undergoing diagnostic and therapeutic hysteroscopy.
- Trial name
- NCT04762147
- Testing
- paracetamol, the group P, fentanyl, group-F administered as an active comparator
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Knee Arthritis
The Efficacy of Collaborative Patient Education on Total Knee Arthroplasty
This project is about the integrated rehabilitation program for the patients receiving total knee arthroplasty. The investigators are monitoring the WOMAC(Western Ontario and Mcmaster University Arthritis Index)/ Pain…
- Trial name
- NCT05346822
- Testing
- integrated rehabilitation (the collaborative patient education)
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Complication, Postoperative, Perioperative/Postoperative Complications
The Impact of Prehabilitation Bundle on Perioperative Outcome for Frail Elderly Patients Undergoing Major Abdominal Surgery
This study aims to study the efficacy of a preoperative "bundle" of interventions, which consists of preoperative physiotherapy, nutritional support and cognitive exercises on elderly frail patients undergoing major abdominal…
- Trial name
- NCT02921932
- Testing
- Ensure, Resource 2.0 and Glucerna, Cognitive Training, Memory Card Game, 'Threshold' Inspiratory Muscle Trainer, Respironics of New Jersey Inc
- Where
- Singapore
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Osteoarthritis, Knee
Perineural Steroids for Peripheral Nerve Blocks
This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.
- Trial name
- NCT02462148
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Critical Limb Threatening Ischaemia, Depression Disorder
Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
Mental health disorders are common in older people and are often unrecognised. Those living with mental health disorders who are being considered for vascular surgery have worse post operative outcomes, including longer length of…
- Conditions
- Critical Limb Threatening Ischaemia, Depression Disorder, Anxiety
- Trial name
- NCT07529886
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Perioperative Care, Pediatric Anesthesia
Giving Children a Voice in Paediatric Anaesthesia
This project will identify the research priorities for paediatric anaesthesia and perioperative medicine in participating countries and highlight areas where further research and information can be provided to optimise the…
- Conditions
- Perioperative Care, Pediatric Anesthesia, Pain Management, Anxiety
- Trial name
- TR-VP26 (NCT07524049)
- Where
- 7 sites in Switzerland
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Perioperative/Postoperative Complications, Drug-Induced Anaphylaxis
Perioperative Anaphylaxis in Patients Attending University Hospitals (Egypt - UK).
Perioperative anaphylaxis is associated with significant morbidity and mortality. Most textbooks describe it as a rare event of the order of 1 in 10 to 1 in 20,000 general anaesthetic cases.
- Trial name
- NCT03393091
- Where
- 2 sites in Egypt, United Kingdom
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Assiut University
Delirium, Dementia, Amnestic, Cognitive Disorders, Postoperative Complications
Postoperative Cognitive Dysfunction in Geriatric Patients
Geriatric patients have a high risk of developing postoperative cognitive deficits. Hypothetical causes are insufficient intraoperative cerebral perfusion or drugs that are administered in the perioperative setting.
- Conditions
- Delirium, Dementia, Amnestic, Cognitive Disorders, Postoperative Complications, Memory Disorders
- Trial name
- NCT00512200
- Where
- Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Music Therapy, Anxiety
Therapy on Perioperative Anxiety and Pain in Patients
This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section.
- Conditions
- Music Therapy, Anxiety, Health Education
- Trial name
- NCT06970431
- Testing
- eoperative Education + Intraoperative Music Therapy Arm, Preoperative Education Alone Arm
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Obesity; Drug
Adequacy of Perioperative Cefuroxime Dosage According to the BMI
This study evaluates the dosage of perioperative cefuroxime for obese patients. Dosage was increased if the BMI was over 30kg/m*m and as well over 50kg/m*m. Drug levels were measured in blood and tissue.
- Trial name
- NCT03141476
- Testing
- Cefuroxime 1,5g, Cefuroxime 3g, Cefuroxime 4,5g
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Perioperative Complication, Perioperative/Postoperative Complications
Registry of Anesthesia and Perioperative Medicine
To assess mortality and morbidity associated to anesthesia interventions
- Conditions
- Perioperative Complication, Perioperative/Postoperative Complications, Anesthesia Morbidity, Anesthesia; Adverse Effect
- Trial name
- RAMP (NCT05869578)
- Testing
- Anesthesia Intervention
- Where
- Chile
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Analgesic Drug Dependence
Intravenous Lidocaine for Perioperative and Postoperative Analgesia
Postoperative pain continues to be untreated despite the application of multimodal analgesia, medication and new analgesic techniques.
- Trial name
- NCT03921567
- Testing
- Lidocaine Hydrochloride, Lidocaine Hydrochloride and Ketamine
- Where
- 2 sites in Kosovo
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Rajmonda Nallbani-Komoni
Osteoarthritis,Knee
Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
The purpose of this study is to compare different medication combinations used in a periarticular injection after total knee replacement surgery(TKR).
- Trial name
- NCT01042093
- Testing
- Ropivacaine, Toradol, Clonidine
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Towson Orthopaedic Associates
Anxiety, Surgery
Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients.
- Conditions
- Anxiety, Surgery, Drug Toxicity, Anesthesia
- Trial name
- NCT03882541
- Testing
- Music therapy, Sedation with midazolam
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de l'Anoia
Risk
Remembering Risk Using Visual Risk Display of MINS to Obtain Informed Consent to Undergo Elective Surgery
Disclosure of anticipated risks to individuals considering undergoing an elective operative procedure is an important aspect of informed consent process.
- Trial name
- NCT05098535
- Testing
- Visual Aid, Scripted Risk Discussion
- Where
- Canada
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Queen's University
Enhanced Recovery After Surgery, Perioperative Care
RIDECLAS: Delphi Classification of RICA Pathway Recommendations
RIDECLAS is an observational, prospective, non-interventional consensus study using a modified Delphi methodology. The study aims to obtain expert consensus on the classification and final formulation of recommendations for the…
- Conditions
- Enhanced Recovery After Surgery, Perioperative Care, Surgical Care
- Trial name
- RIDECLAS (NCT07615855)
- Testing
- Modified Delphi questionnaire
- Where
- Spain
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza