Clinical trials: Perioperative Outcomes
Obstetric Complication, Gynecologic Cancer
Lung Ultrasound in Critically Ill Obstetrics and Gynecological Patients
Pulmonary dysfunction aggravates the illness of critically ill obstetrics and gynecological patients. Early identification with bedside technique and prompt management may improve the outcome of critical care in this vulnerable…
- Conditions
- Obstetric Complication, Gynecologic Cancer, Lung Diseases, Ultrasound
- Trial name
- POLUS (NCT06728709)
- Testing
- ultrasound detection of any abnormal ultrasonographical findings.
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Ain Shams University
Pulmonary Complication
Perioperative Lung Ultrasonography for Fast-track Cardiac Surgery
The investigators evaluate the usefulness of lung ultrasonography in the perioperative period for postoperative outcomes in children undergoing fast track cardiac surgery.
- Trial name
- NCT03527862
- Testing
- Treatment according to lung ultrasonography
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seoul National University Hospital
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
SPI-directed Analgesia for Vitreoretinal Surgeries
The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- SPIVS (NCT02973581)
- Testing
- Metamizol, Acetaminophen, 0,5 % bupivacaine with of 2% lidocaine
- Where
- Poland
- Volunteers
- 176 people
- Sponsor
- Medical University of Silesia
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
Liver Transplantation, Body Composition
Impact of Perioperative Body Composition Abnormalities on Patient Outcomes After Liver Transplantation
Accumulating evidence suggests the prognostic significance of body composition in chronic diseases and neoplastic diseases. CT imaging-based body composition abnormalities are significantly associated with post-LT adverse…
- Trial name
- NCT06209775
- Volunteers
- 996 people
- Sponsor
- Zhejiang University
Bariatric Surgery Candidate
Prospective Robotic-assisted Revisional Bariatric Study
Very few studies have compared robotic-assisted (RRBS) versus laparoscopic revisional bariatric surgeries (LRBS). To date, there has not been a prospective study comparing the perioperative outcomes of patients undergoing…
- Trial name
- NCT04506190
- Testing
- Revisional bariatric surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Intuitive Surgical
Kidney Transplant; Complications
Effects of Graft Vascular Dimensions on Surgical and Functional Outcomes of Living Donor Kidney Transplantation
1. Correlate the radiological and intraoperative measuring of the vascular dimensions, 2. Assess the effect of the vascular dimensions on the short-term surgical complications and 3.
- Trial name
- NCT05797389
- Volunteers
- 30 people
- Sponsor
- Assiut University
Adolescence Idiopathic Scoliosis, Preoperative Anxiety
the Effect of the Preoperative Information Method on Intraoperative Anxiety and Postoperative Outcomes in AIS Patients: a Randomized Clinical Trial
Due to the increasing use of smartphones and social media in contemporary times, adolescents experience a rapid loss of attention while reading or listening.
- Conditions
- Adolescence Idiopathic Scoliosis, Preoperative Anxiety, Postoperative Pain After Spinal Surgery
- Trial name
- NCT07902674
- Testing
- İntervention 1: Video-Based Preoperative Education, İntervention 2: Brochure-Based Preoperative Education, Routine Verbal Preoperative Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gazi University
Perioperative Myocardial Infarction, Disability
Troponin Elevation After Major Noncardiac Surgery 2
Major adverse cardiac events (MACE) are a leading cause of mortality in patients undergoing noncardiac surgery. Patients with perioperative myocardial injury (PMI), defined as either myocardial infarction and lower elevations in…
- Conditions
- Perioperative Myocardial Infarction, Disability, Perioperative/Postoperative Complications
- Trial name
- TEAMS2 (NCT03408522)
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 1,000 people
- Sponsor
- UMC Utrecht
Liver Transplant Disorder
Perioperative Factors and Living Donor Liver Transplantation
Liver transplant surgery is one of the treatments provided to patients suffering from end-stage liver disease, and has a successful treatment prognosis.
- Trial name
- NCT06312098
- Testing
- remote ischemic preconditioning (RIPC)
- Volunteers
- 533 people
- Sponsor
- Min Suk Chae
Retrograde Intrarenal Surgery
General Versus Spinal Anesthesia in RIRS
The impact of anesthesia type on Retrograde Intrarenal Surgery (RIRS) outcomes remains a subject of ongoing debate. Several studies have compared general anesthesia (GA) and spinal anesthesia (SA) in endourological procedures…
- Trial name
- NCT07664384
- Where
- Egypt
- Volunteers
- 252 people
- Sponsor
- South Valley University
Paediatric Surgery, Perioperative/Postoperative Complications
An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery
Access to safe surgery is a basic human right. This is highlighted by the work of the Lancet Commission on Global Surgery. There is a large burden of surgical disease in the paediatric surgical population with a large unmet need.
- Conditions
- Paediatric Surgery, Perioperative/Postoperative Complications, Perioperative Outcomes, Hospital Mortality
- Trial name
- ASOS-Paeds (NCT05061407)
- Where
- 2 sites in South Africa, Sudan
- Volunteers
- 8,625 people
- Sponsor
- University of KwaZulu
Outcomes Following Major Surgery in Older Adults
The Irish Perioperative OutcomeS (IPOS) Study
The Irish Perioperative OutcomeS (IPOS) Study aims to better understand the factors that influence recovery and outcomes in older adults undergoing major surgery in Ireland.
- Trial name
- IPOS (NCT07895199)
- Volunteers
- 500 people
- Sponsor
- University College Hospital Galway
Postoperative Complications, Alcohol Use Disorder
Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
This study aims to see if there's a link between a substance called phosphatidylethanol (PEth) and how patients who have surgery at University Hospitals do after surgery.
- Trial name
- NCT06864819
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University Hospitals Cleveland Medical Center
Jejunostomy, Gastrostomy
Anesthesia Management and Perioperative Outcomes in Awake Jejunostomy and Gastrostomy
Patients requiring surgical jejunostomy or gastrostomy often have advanced malignancy, multiple comorbidities, and limited physiological reserve, which may increase the risks associated with general anesthesia.
- Conditions
- Jejunostomy, Gastrostomy, Anesthesia, Regional
- Trial name
- Awake Jejunost (NCT07885358)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Samsun University
Urothelial Carcinoma
Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma
The goal of this study is to conduct the first randomized-controlled trial to determine the oncologic efficacy of lymph node dissection in participants with upper tract urothelial cell carcinoma.
- Trial name
- NCT06262516
- Testing
- Nephroureterectomy, Lymph Node Dissection
- Where
- 4 sites in United States
- Volunteers
- 94 people
- Sponsor
- Case Comprehensive Cancer Center
Perioperative Myocardial Infarction, Disability
TEAMS (Troponin Elevation After Major Surgery) Study
Background to main study question: Cardiac complications are a common cause of morbidity after non-cardiac surgery. Patients with perioperative myocardial injury (both MI, and lower levels of cardiac troponin elevation)…
- Trial name
- TEAMS (NCT02146560)
- Where
- Canada
- Volunteers
- 267 people
- Sponsor
- University Health Network, Toronto
URTI, Postoperative Complications
Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic
The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional…
- Conditions
- URTI, Postoperative Complications, COVID - 19, Elective Non-cardiac Surgery
- Trial name
- URTI (NCT07157111)
- Where
- China
- Volunteers
- 2,392 people
- Sponsor
- aijun xu
Postoperative Complications
Perioperative Muscle Relaxant and Postoperative Outcomes
Muscle relaxant is usually needed for surgery. However, the optimal depth of neuro-muscular blockade is still on debate. Deep neuro-muscular blockade may benefit the patients during surgery, but may increase the risk of residual…
- Trial name
- POMPO (NCT04371588)
- Testing
- No Response to Train of Four Stimulation, 1-2 Response to Train of Four Stimulation
- Where
- 9 sites in China
- Volunteers
- 999 people
- Sponsor
- Air Force Military Medical University, China
Colon Cancer
The Influence of Perioperative Administration of Dexmedetomidine on Inflammation Response and Postoperative Outcomes in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Double Blind Randomized Controlled Trial
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has been reported to be an effective treatment approach for peritoneal cancer, however, the stress response to HIPEC is major neuroendocrine and…
- Trial name
- NCT03370588
- Testing
- dexmedetomidine, Normal saline
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University