Clinical trials: Perioperative Pain Control
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Dermatochalasis of Upper Eyelid, Blepharoplasty
Perioperative Haemostasis, Procedure-Related Pain After Physiological or Pharmacological Modifications of Local Anaesthesia Around the Eyes
The goal of this clinical trial is to determine whether buffering, warming, or addition of hyaluronidase or tranexamic acid to lignocaine during eyelid injection of local anaesthesia reduce injection pain and procedure-related…
- Trial name
- P4LE (NCT07734740)
- Testing
- Sodium Bicarbonate (NaHCO3), Warmed lignocaine, Hyaluronidase Injection
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Pain, Postoperative
Gastrectomy at Low Pressure Trial - (GALPT)
The study is designed to compare two different insufflation devices during surgery, CONMED AirSeal to Lexicon, during Laparoscopic Sleeve Gastrectomy.
- Trial name
- GALPT (NCT07313930)
- Testing
- AirSeal® Insufflation System (AIS), Lexicon AP 50/30 Insufflator
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- SurgiQuest, Inc.
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Pain
Perioperative Lidocaine and Ketamine in Abdominal Surgery
The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
- Trial name
- NCT04084548
- Testing
- Lidocaine and ketamine, Lidocaine, Ketamine
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Appendicitis
Perioperative Pain Management of Pediatric Appendectomy Patients
Acute appendicitis is the most common illness that brings pediatric patients to the hospital for surgical treatment. Abdominal pain is the symptom because of which the patients go to the hospital.
- Trial name
- umpikipu (NCT02580487)
- Testing
- appendicectomy
- Where
- Finland
- Volunteers
- 178 people
- Sponsor
- Kuopio University Hospital
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Prostatectomy, Pain
Impact of Perioperative Analgesia in Prostatectomy Patients on Early Quality of Recovery (SPITALIDO)
The rationale behind this RCT is to assess within 24 hours after surgery the quality of recovery of prostatectomy patients treated with 3 different analgesia concepts (intraoperative spinal analgesia, transversus abdominis plane…
- Trial name
- SPITALIDO (NCT03618693)
- Testing
- Spinal anesthesia, TAP Block, Standard
- Where
- Switzerland
- Volunteers
- 142 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Opioid-use Disorder, Opioid Use Disorder, Mild
Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms
The purpose of this research study is to compare two ways of managing pain in people who are taking buprenorphine and are scheduled to undergo surgery.
- Trial name
- NCT04091009
- Testing
- Buprenorphine/naloxone
- Sponsor
- Massachusetts General Hospital
Elective Spine Surgery Receiving Pre and/or Postoperative Pain Control With Opioids
Impact of Daily, Digital and Behavioral Tele-health Tapering Program for Perioperative Surgical Patients Exposed to Opioids and Benzodiazepines.
The purpose of this study is to examine the safety, acceptability, and feasibility of a controlled taper off of opioids and/or benzodiazepines, with the use of behavioral health tele-health based therapy services, in the…
- Trial name
- NCT04787692
- Testing
- Opioid and Benzodiazepine Naive-patients, Opioid and Benzodiazepine Tolerant-patients
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Knee Osteoarthritis
Comparison of Postoperative Pain Score Between Perioperative Intravenous Ketamine and Placebo in Patients Undergoing Unilateral Total Knee Arthroplasty Under General Anesthesia
The goal of this clinical trial is to compare postoperative pain score between perioperative intravenous ketamine and placebo in patients undergoing unilateral total knee arthroplasty under general anesthesia.
- Trial name
- NCT06267638
- Testing
- Ketamine group
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Thailand
Regional Anesthesia Morbidity, Hip Surgeries
Pericapsular Nerve Group Block vs. Fascia Iliaca Compartment Block vs. Caudal Block for Hip Surgeries
The study aims to compare the effect of pericapsular nerve group block versus fascia iliaca compartment block versus caudal block regarding Postoperative analgesia in children undergoing hip surgeries.
- Conditions
- Regional Anesthesia Morbidity, Hip Surgeries, Perioperative Analgesia
- Trial name
- NCT07137962
- Testing
- PENG Block, FICB Block, Caudal Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.
Perioperative Melatonin in Lumbar Laminectomy
Patients undergoing lumbar laminectomy surgery will receive either 5 or 10 mg melatonin or placebo once the evening before surgery and again 90 minutes before surgery.
- Trial name
- NCT01126294
- Testing
- 5 mg melatonin, 10 mg melatonin
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Pain, Hip Fractures
Comparison Effects of Two Regional Anesthetic Technique on Pain During High Risk Hip Fracture Surgery
In this study, our is to compare effect of lumbosacral plexus and sacral plexus + suprainguinal fascia iliaca plane block on perioperative pain via analgesia nociceptive index monitor on high-risk patients undergoing hip fracture…
- Conditions
- Pain, Hip Fractures, Perioperative Analgesia
- Trial name
- NCT05862922
- Testing
- Analgesia Nosiception İndex Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Colorectal Cancer
Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery
Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements
- Trial name
- NCT04294953
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cervical Cancer Stage IB2, Cervical Cancer Stage IIa
Minimally Invasive Radical Hysterectomy Using Endoscopic Stapler in Stage IB2 or IIA1 Cervical Cancer
This study is a multicenter, open-label, non-inferiority, randomized controlled, investigator-initiated clinical trial comparing the efficacy and safety of open radical hysterectomy versus minimally invasive radical hysterectomy…
- Trial name
- SOLUTION2 (NCT07256977)
- Testing
- Open radical hysterectomy, Minimally invasive radical hysterectomy
- Where
- South Korea
- Volunteers
- 494 people
- Sponsor
- Seoul National University Hospital
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Pain
Erector Spinae Plane Block for Carotid Endarterectomy
The purpose of this study is to test the hypothesis that erector spinae plane block will decrease intraoperative local anesthetic and postoperative analgesic consumption in patients undergoing carotid endarterectomy.
- Trial name
- NCT04224844
- Testing
- Erector spinae plane block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Antalya Training and Research Hospital
Degenerative Joint Disease of Shoulder
Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)
The main purpose of this research is to find out if a treatment called cryoneurolysis can reduce pain after reverse total shoulder replacement surgery. This treatment uses cold to temporarily block a nerve in the shoulder.
- Trial name
- NCT07125833
- Testing
- Cryoneurolysis, No cryoneurolysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- North Texas Medical Research Institute, PLLC