Clinical trials: Perioperative Pain Control
Perioperative Complication, Nursing Caries
The Effects of Listening Music During Breathing Exercises
Background and purpose : This study aims to analyze the effects of listening to music during deep breathing and coughing exercises on vital sings and pulmonary functions in patients, who underwent video assisted thoracoscopic…
- Conditions
- Perioperative Complication, Nursing Caries, Pain, Postoperative
- Trial name
- NCT05329519
- Testing
- Listening music
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Opioid Use, Cytokine
Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain
Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few.
- Trial name
- NCT03825471
- Testing
- electrotherapy, Opioid Anesthetics, colon cancer surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Pain, Postoperative
Toradol v. Celecoxib for Postoperative Pain
Randomized control trial between ketorolac versus celecoxib for postoperative pain following hysterectomy.
- Trial name
- POP (NCT03331315)
- Testing
- Celecoxib, Ketorolac
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Michael Ulm, MD
Hip Fractures, Anesthesia Local
Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
The main objective of the trial is to complete a double-blinded randomized controlled trial with crossover design of a lumbosacral plexus block with the Suprasacral Parallel Shift technique guided by ultrasound/magnetic resonance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Perioperative
- Trial name
- NCT02593370
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Thomas F. Bendtsen
Shoulder Arthritis, Anesthesia, Local
Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial
Total shoulder arthroplasty (TSA) is a common and effective treatment for end-stage shoulder pathologies. Over the past 25 years, implant designs have evolved and the indications for joint replacement have expanded significantly…
- Conditions
- Shoulder Arthritis, Anesthesia, Local, Local Infiltration
- Trial name
- NCT05908851
- Testing
- 100 mL of 0.9% normal saline (57ml), 0.5% ropivacaine (40 ml), 10 mg morphine (10 mg/ml), 0.1 mg of epinephrine (0.1 mg/ml), and 30 mg of ketorolac (30 mg/ml)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post Operative Pain, Hyperalgesia
Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
Background: In perioperative period inhibition of N-Methyl-D-Aspartate receptor prevents opioid-induced hyperalgesia and reduce postoperative opioid requirement after abdominal surgery.
- Trial name
- NCT01594047
- Testing
- ketamine infusion, Methadone PCA
- Where
- Italy
- Volunteers
- 113 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Spine Surgery, Pain After Surgery
Impact of NOL - Nociception Level Index Intraoperative Monitoring on Perioperative Outcomes in Spine Surgery - a Quality Improvement Pilot
The objective of this study is to evaluate the clinical impact of the NOL nociception level index monitoring on intraoperative and post operative patient outcomes and institutional metrics when used to guide intraoperative…
- Conditions
- Spine Surgery, Pain After Surgery, Anesthesia , Analgesia
- Trial name
- NCT07608276
- Testing
- NOL guided intraoperative analgesia
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medasense Biometrics Ltd
Pharmacogenetics, Anesthesia
Perioperative Pharmacogenomic Testing
This is a single centre, prospective feasibility study and pilot randomised controlled trial of patients scheduled for elective intermediate or major non-cardiac surgery.
- Trial name
- PPGx (NCT05063838)
- Testing
- Pharmacogenomic optimisation of anaesthetic medications
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Prostate Biopsy
Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia:
The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a…
- Trial name
- HYPNOSURG-VR (NCT06691438)
- Testing
- prostate biopsy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Bypass Grafting or Heart Valve Surgery Via Median Sternotomy
Transversus Thoracis Muscle Plane Block Plus Rectus Sheath Block in the Perioperative Pain Management of Cardiac Surgery
An emerging regional block technique, transverse thoracic muscle block covers the T2-T6 intercostal nerves and can effectively relieve perioperative pain during median sternotomy.
- Trial name
- NCT04838132
- Testing
- Bilateral transversus thoracis muscle plane and rectus sheath block with ropivacaine, Bilateral transversus thoracis muscle plane and rectus sheath puncture with saline
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangzhou First People's Hospital
Knee Arthroplasty
Perioperative Analgesia After Knee Arthroplasty
The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The…
- Trial name
- NCT01225484
- Testing
- Continuous femoral nerve block + periarticular infiltration, Intraarticular and periarticular ropivacaine
- Where
- Austria
- Volunteers
- 123 people
- Sponsor
- Landeskrankenhaus Feldbach
Volume Expansion, Fluid Responsiveness
Ability of Changes in Analgesia Nociception Index to Assess the Stroke Volume Effects of a Volume Expansion of 250ml of Crystalloid in the Operating Room
Volume expansion is the cornerstone of perioperative hemodynamic optimization. The main objective of volume expansion is to increase and maximize stroke volume. Hemodynamic changes have an impact on the autonomic nervous system.
- Trial name
- REVANI (NCT04223414)
- Testing
- Analgesia Nociception Index (ANI)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Bordeaux
Pain, Postoperative
Caffeine Study for Pain Control Following Total Joint Replacement
A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total…
- Trial name
- NCT04280263
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rothman Institute Orthopaedics
Pain, Nerve Block
The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy
The endoscopic binostril transnasal transsphenoidal resection of pituitary procedures often cause intense pain which is difficult to suppress at the depth of conventional general anesthesia, resulting in severe hemodynamic…
- Trial name
- NCT05555147
- Testing
- nerve block with 0.5% ropivacaine, without any nerve block
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Breast Cancer, Post Operative Pain
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
This study aims to evaluate whether perioperative mirogabalin can reduce postoperative pain and morphine consumption in female patients undergoing modified radical mastectomy for breast cancer.
- Trial name
- NCT07880821
- Testing
- Mirogabalin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Hip Fractures, Ultrasound-guided Nerve Block
Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip Fracture
Hip fractures are a growing public health concern globally due to the aging population, with high incidence and significant mortality rates one year post-fracture.
- Conditions
- Hip Fractures, Ultrasound-guided Nerve Block, Perioperative Analgesia
- Trial name
- NCT06728033
- Testing
- supra-inguinal fascia iliaca compartment block, Tramadol
- Where
- China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
Thoracic Diseases, Thoracic Surgery
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain.
- Conditions
- Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative
- Trial name
- SAPB (NCT03768193)
- Testing
- Deep serratus anterior plane block, Surgically-placed paravertebral block
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
This study will recruit women scheduled to undergo vaginal apical suspension surgery (either uterosacral ligament suspension or sacrospinous ligament fixation) with or without other prolapse or anti-incontinence procedures.
- Trial name
- NCT05658887
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joseph Kowalski
Inflammatory Bowel Diseases, Anesthesia
HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia
The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease
- Trial name
- HYSTERIA (NCT03261414)
- Testing
- Hypnosis, usual care
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Lille
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria