Clinical trials: Perioperative Period
Osteoarthritis, Knee
Perineural Steroids for Peripheral Nerve Blocks
This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.
- Trial name
- NCT02462148
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hypothermia
Efficacy of Warming Garment in the Perioperative Period With Integrated Chemical Heat Packs to Maintain Normothermia
Efficacy of Stand-alone, Non-tethered, Self-applying Warming Garment in the Preoperative, Intraoperative and Postoperative Recovery Period; Using an Integrated Chemical Heat Pack Construction, With a View to Maintaining…
- Trial name
- NCT02905708
- Testing
- Air-Activated heating packs, Forced Air Warming Device
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr K Services PC
Cardiopulmonary Bypass
Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor
In previous studies, 90% of patients who underwent elective cardiopulmonary bypass procedure manifested CD4 counts of less than 500 cells/microliter in the immediate (day 1) post-operative period.
- Trial name
- NCT00385450
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Adult ALL, Surgery
Application of Wearable Technology in High-risk Surgical Patients in the Perioperative Period
Unrecognised changes in patients' vital signs after surgery can result in preventable complications. Current standard practice includes routine monitoring of patient vital signs up until hospital discharge.
- Conditions
- Adult ALL, Surgery, Anesthesia, Postoperative Complications
- Trial name
- NCT05642988
- Testing
- LifeSignals 1AX Biosensor
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Surgical Patient, Nursing Caries
The Effect of Mobile Application Used by Patients
The aim of this study is to evaluate whether a patient-centered mobile application used during the perioperative period can improve anxiety, complications, comfort, and patient satisfaction compared to standard care.
- Conditions
- Surgical Patient, Nursing Caries, Laparoscopic Cholecystectomy
- Trial name
- NCT06891339
- Testing
- mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Thoracic Surgery
High-Flow Nasal Catheter (HFNC) Compared With Conventional Oxygenation
The purpose of this study, is to clarify whether there is benefit from the perioperative use of HFNC in thoracic surgeries, from intubation to the postoperative period, evaluating hipoxemia during orotracheal intubation…
- Trial name
- NCT05910788
- Testing
- high flow nasal cannula
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Pulmonary Embolism
The Clinic Study to Prevent Pulmonary Embolism in Patients With General Anesthesia Operation in Perioperative Period
The purpose of this study is to investigate the prevention of Pulmonary Embolism in Patients who With General Anesthesia Operation in Perioperative Period.
- Trial name
- NCT02460952
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Stress, Physiological, Stress, Psychological
Impact of Music in the Preoperative Stress of Children Undergoing General Surgery
Preoperative anxiety and stress are present in up to 60% of pediatric patients undergoing surgery, having a great physiological and emotional impact on children in both the short and long term.
- Trial name
- NCT02947919
- Testing
- Music
- Where
- Chile
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Anticoagulants and Bleeding Disorders
Anticoagulation and Antiplatelet Management During Perioperative Period
the investigators hypothesize that patients do not understand these therapies, and that they are poorly undertaken. In some cases, the anesthesiologist does not understand correctly the indication of the treatment due to lack of…
- Trial name
- OMAHA (NCT03871283)
- Where
- Belgium
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Airway Management, Education
The Training and Evaluate Effect on Clinical Airway Management
In this self-control experiment, anesthesiologists with limited experiments of bronchoscopy working in anesthesiology department in Peking Union Medical College Hospital will receive a training and evaluation procedure in…
- Conditions
- Airway Management, Education, Bronchoscopy
- Trial name
- NCT03854760
- Testing
- anesthesiologist with limited experiment
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Frail Elderly Syndrome
Home-based Prehabilitation for Elderly Patients
As a consequence of the increasing life expectancy hospitals are seeing a growing number of elderly patients undergoing elective surgery.
- Trial name
- TRAilty (NCT03964363)
- Testing
- Unsupervised home-based physical prehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance
Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery
The goal of this clinical trial is to learn whether physicians can associate evidence of myocardial injury after surgery with findings obtained from submaximal cardiopulmonary exercise testing.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period
- Trial name
- EnhanceMINS (NCT06474754)
- Testing
- High-sensitivity troponin, serum, Submaximal Cardiopulmonary Exercise Testing, Duke Activity Status Index
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Postoperative Pain, Postoperative Pain Management
Evaluating the Efficacy and Utility of the Automated Pupillometer in Pain Assessment and Opioid Administration Guidance During the Perioperative Period: A Randomized Controlled Trial
Effective intraoperative and postoperative pain management is critical for patient comfort and recovery, yet traditional methods for assessing pain under general anaesthesia are limited by their subjective nature and reliance on…
- Trial name
- NCT07614607
- Testing
- Opioid Analgesic, automated pupillometry
- Where
- Malaysia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Acute Respiratory Failure With Hypercapnia
High Flow Nasal Oxygen Therapy in Perioperative Period of the Adult With Hypercapnic and Hypoxemic Respiratory Faliure
The purpose of this study is to determine the impact of hign-flow nasal therapy on the adult with hypercapnia and hpoxemia respiratory faliure in comparison with standard oxygen therapy ang noninvasive ventilation.
- Trial name
- NCT03229460
- Testing
- standard low flow therapy, high flow nasal oxygen therapy, association of high flow nasal oxygen therapy and non invasive positive pressure ventilation
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Participants' Pain,Quality of Life and Hospital Satisfaction
The Effect of "Adjacent Bed Effect" Induced by Anxiety on the Perioperative Period of Patients With Chocolate Cyst of Ovary
The "adjacent bed effect" caused by anxiety leads to poor recovery of participants after ovarian chocolate cyst surgery, including pain and quality of life, and affects participant satisfaction with the hospital.
- Trial name
- NCT06215482
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Fusion of Spine, Lumbar Region
The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion
Simple explanation and rationale: Recovery after spine surgery is usually accompanied by severe pain which has traditionally been managed with opioids.
- Trial name
- NCT03104816
- Testing
- Acetaminophen IV Soln 10 MG/ML, Acetaminophen, Hydromorphone
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Postoperative Complications, Elderly
Elderly Patients Undergoing Surgery During Perioperative Period
The elderly patients have poorer overall conditions and have lower tolerance to trauma, anesthesia, and surgery. Therefore, the incidence of postoperative complications is relatively higher.
- Conditions
- Postoperative Complications, Elderly, Postoperative Delirium (POD), Risk Prediction Model
- Trial name
- NCT07314762
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Dexmedetomidine, General Anesthesia
Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period
Perioperative stress may increase the incidence of adverse events in the cardiovascular system and lead to poor prognosis. Dexmedetomidine is a highly selective α2 adrenergic receptor agonist, which can inhibit stress response…
- Conditions
- Dexmedetomidine, General Anesthesia, Cardiac Electrophysiology, Cardiac Function
- Trial name
- NCT04577430
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Opioid-use Disorder, Pain, Acute
Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use
The aim of this study is to determine the effect of continuation of buprenorphine/naloxone in patients with history of Opioid Use Disorder (OUD) scheduled for surgery compared to reduced dose buprenorphine/naloxone prior to…
- Conditions
- Opioid-use Disorder, Pain, Acute, Surgery
- Trial name
- NCT03266445
- Testing
- buprenorphine/naloxone
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital