Clinical trials: Perioperative Period
Total Knee Arthroplasty, Intraoperative Hypothermia
The Effect of Preoperative Active Warming on Intraoperative Body Temperature
A randomized controlled study was conducted to examine the effect of active warming before total knee arthroplasty on intraoperative body temperature and comfort.
- Trial name
- NCT05334589
- Testing
- Prewarming
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Mitral Valve Replacement, Transfusion Reaction
Blood Transfusion Management in Patients With Mitral Valve Replacement in China
The evaluation uses ΔHb as an independent factor combined with artificial intelligence (AI) to predict its impact on the prognosis and blood transfusion of patients undergoing cardiac surgery, thereby guiding perioperative…
- Conditions
- Mitral Valve Replacement, Transfusion Reaction, Blood Transfusion Complication
- Trial name
- NCT03885570
- Testing
- Mitral valve replacement
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pulmonary Embolism
The Clinic Study to Prevent Pulmonary Embolism in Patients With General Anesthesia Operation in Perioperative Period
The purpose of this study is to investigate the prevention of Pulmonary Embolism in Patients who With General Anesthesia Operation in Perioperative Period.
- Trial name
- NCT02460952
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Surgical Procedure, Non-cardiac, Cardiovascular Disease Patients
Perioperative Ischemia Versus Perioperative Bleeding During Non-cardiac Surgery in Cardiac Patients
The aim of the study is to analyze the present use of antithrombotic therapy on a large cohort of consecutive cardiacs undergoing non-cardiac surgery.
- Conditions
- Surgical Procedure, Non-cardiac, Cardiovascular Disease Patients, Perioperative Period
- Trial name
- PRAGUE-14 (NCT01897220)
- Where
- 2 sites in Czechia
- Volunteers
- 1,200 people
- Sponsor
- Charles University, Czech Republic
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Intensive Cholesterol-Lowering Within 24 Hours of PCI Perioperative Period
This project team is conducting a multicenter randomized controlled study, aiming to administer PCSK9 inhibitors subcutaneously as early as possible within 24 hours during the perioperative period of AMI (included <24h STEMI and…
- Trial name
- INCLINE-AMI (NCT07290699)
- Testing
- Recaticimab
- Volunteers
- 2,442 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Pain, Postoperative, Infant Behavior
Healthcare Provider Behavior and Children's Perioperative Distress
The goal of this randomized trial is to examine the effectiveness of a Provider Tailored Intervention for Perioperative Stress (P-TIPS) in preventing high anxiety and improving the recovery process in children undergoing surgery.
- Trial name
- NCT01878747
- Testing
- Provider Tailored Intervention for Perioperative Stress
- Where
- 6 sites in United States, Canada
- Volunteers
- 1,471 people
- Sponsor
- University of California, Irvine
Rheumatoid Arthritis
Anti-TNFα Use During Elective Foot and Ankle Surgery in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a frequent inflammatory arthritis that can lead to severe joint deformity and often requires orthopaedic surgical interventions.
- Trial name
- NCT02242474
- Testing
- Anti-TNF suspended perioperatively, Anti-TNFα continued perioperatively
- Where
- Canada
- Volunteers
- 660 people
- Sponsor
- CHU de Quebec-Universite Laval
Stress, Physiological, Stress, Psychological
Impact of Music in the Preoperative Stress of Children Undergoing General Surgery
Preoperative anxiety and stress are present in up to 60% of pediatric patients undergoing surgery, having a great physiological and emotional impact on children in both the short and long term.
- Trial name
- NCT02947919
- Testing
- Music
- Where
- Chile
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Perioperative Complication
SGLT2 Inhibitors and Perioperative Period
The expanded use of SGLT2 inhibitors motivates us to assess the role of SGLT2 inhibitors in perioperative period on patients who will undergo cardiac surgery in Assiut University.
- Trial name
- NCT06326528
- Testing
- SGLT2 inhibitor
- Volunteers
- 100 people
- Sponsor
- Assiut University
Informed Consent
A Survey of Patient's Attitudes Towards Consent For Clinical Research In Anesthesiology
In most current academic anesthesia groups, it appears that consent for research is acquired on the day of surgery. This practice raises concerns because the hospital may be regarded as a coercive environment and there may be the…
- Trial name
- NCT01546194
- Testing
- Phone call explaining the research project
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Endeavor Health
Cervical Myelopathy
ERAS in Posterior Approach of Cervical Spine Operation
Enhanced recovery after surgery (ERAS) strategy has been used in the patient management of different diseases. This study aims to evaluate the effectiveness of ERAS in the perioperative period of posterior approach of cervical…
- Trial name
- NCT04962256
- Testing
- Enhanced recovery after surgery
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Peking University Third Hospital
Diastolic Dysfunction
Perioperative Measurements of Diastolic Function in Cardiac Surgery
This observational clinical trial will investigate the following perioperative indices relating to cardiac surgery: 1. The significance of measurements involving left heart relaxation (LV diastolic function) and its relation to…
- Trial name
- NCT02285309
- Testing
- Cardiac Surgery and enoximone
- Volunteers
- 100 people
- Sponsor
- University College, London
Pain, Postoperative
Characterization of Bio-psychosocial Pain Profiles in the Perioperative Period
This is a prospective descriptive correlational design looking to characterize postoperative pain variables across various procedures that historically have significant levels of persistent post-surgical pain
- Trial name
- NCT03081299
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Pain
The Preemptive Analgetic Potency of Low Dose S-Ketamine
The primary hypothesis is improved postoperative analgetic quality using S-Ketamine, particularly in patients suffering from chronic pain.
- Trial name
- Miniket (NCT01022840)
- Testing
- S-Ketamine
- Where
- 3 sites in Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Graz
Breast Cancer, Neoadjuvant Chemotherapy
Effect of Neoadjuvant Chemotherapy on Cardiac Function of Perioperative Patients With Breast Cancer and New Strategies for Anesthesia
As is well known, perioperative hemodynamic fluctuations, such as decreased blood pressure and heart rate, and cardiac dysfunction, are common complications after anesthesia.
- Conditions
- Breast Cancer, Neoadjuvant Chemotherapy, Perioperative Period, Anaesthesia
- Trial name
- NCT06497660
- Testing
- Deoxyadrenaline, normal saline
- Where
- China
- Volunteers
- 496 people
- Sponsor
- Fujian Medical University Union Hospital
Perioperative Period, Anesthetic
Correlation Between Perioperative EEG Features and Delirium After General Anesthesia
The goal of this observational study is to compare the perioperative EEG characteristics and the incidence of short-term cognitive dysfunction in patients with postoperative delirium and non-postoperative delirium after elderly…
- Conditions
- Perioperative Period, Anesthetic, Postoperative Cognitive Dysfunction, Postoperative Delirium
- Trial name
- NCT06082024
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fuzhou Hua
Pediatric Orthopedic Surgery
A Short Digital Intervention for Youth Undergoing Major Surgery and Their Parents
The perioperative time, i.e., the time before, during, and directly after surgery, can be stressful for families whose child needs to undergo major orthopedic surgery.
- Trial name
- POPI (NCT07812961)
- Testing
- Psychoeducational single-session intervention for families during the perioperative period
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Helen Koechlin
Anticoagulants and Bleeding Disorders
Anticoagulation and Antiplatelet Management During Perioperative Period
the investigators hypothesize that patients do not understand these therapies, and that they are poorly undertaken. In some cases, the anesthesiologist does not understand correctly the indication of the treatment due to lack of…
- Trial name
- OMAHA (NCT03871283)
- Where
- Belgium
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Ketamine; Depressive Symptom; Neurosurgery; Perioperative Period
Ketamine and Postoperative Depressive Symptom-PASSION
Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay.
- Trial name
- NCT03086148
- Testing
- Ketamine, Normal saline
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Tiantan Hospital