Clinical trials: Periorbital
Skin Health
A Clinical Trial to Evaluate the Effects of a Skin Balm on the Appearance of the Eye Area
This virtual single-group clinical trial aims to evaluate the effects of the Sahajan Golden Glow Balm on the health and appearance of the skin in the periorbital area over a period of 6 weeks.
- Trial name
- NCT06452810
- Testing
- Experimental: Sahajan Golden Glow Balm
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sahajan
Skin Wrinkles
Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles（F-MFR300-RD-003）
This is a multicenter trial with randomized control and evaluator blind method, which meets the screening criteria total of 224 subjects were enrolled and randomly divided into control group and experiment according to 1:1 ratio…
- Trial name
- NCT06565884
- Testing
- Home radiofrequency skin treatment instrument, Ultrasonic coupler for medical purposes
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Flossom (GD) Beauty Technology Co., Ltd.
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Wrinkle, Periorbital
Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles
A Prospective, Multicenter, Single-Arm Clinical Study of 51 study subjects who are seeking a procedure to reduce the appearance of the peri-orbital wrinkles.
- Conditions
- Wrinkle, Periorbital, Tixel 2, Fractional
- Trial name
- NCT04639713
- Testing
- Tixel 2
- Where
- 3 sites in United States, Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Periorbital Wrinkles, Periorbital Area
Non-invasive Rejuvenation of the Periorbital Area and Lower Eyelid
The goal of this clinical trial is to determine the BTL-785-7-11 applicator effectiveness for an under-eye appearance improvement by evaluation of the periorbital area in healthy adult volunteers.
- Conditions
- Periorbital Wrinkles, Periorbital Area, Under-eyes Dark Circles, Crows Feet
- Trial name
- NCT07028203
- Testing
- Treatment with BTL-785 with the applicator BTL-785-7-11
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Periorbital Hyperpigmentation
Physiopathologic Aspects and Quality of Life in Participants With Eye Dark Circles
This study will evaluate the physiopathologic characteristics of dark circles in participants with various ethnicities and Fitzpatrick Skin Types and the impact of the dark circles on the quality of life.
- Trial name
- NCT03400202
- Testing
- Skin imaging, Facial cleanser
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Allergan
Periorbital Area
A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area
This study will evaluate the efficacy of the DIME Beauty Luminosity Eye Serum in improving the appearance of skin in the periorbital eye area. This study will last for 60 days.
- Trial name
- NCT06143033
- Testing
- DIME Beauty Luminosity Eye Serum
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
Wrinkles
Single-Blind, Investigational Device Exemption Paired-Design, Non-Inferiority Trial With Confirmation for the Assessment of the Efficacy and Safety of a Universal Electrosurgical Device for Temporary Improvement of Mild and Moderate Wrinkles Around Both Eye Corners and Both Cheek Folds
Radiofrequency (RF) devices are commonly used for noninvasive facial rejuvenation. This study compared the efficacy and safety of 10THERMA, a newly developed monopolar RF device, with those of the Thermage FLX system.
- Trial name
- NCT07467811
- Testing
- 10THERMA, Thermage FLX
- Where
- 3 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TENTECH INC.
Periorbital Wrinkles
Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles
This is a prospective, interventional, evaluator-blinded, multi-center clinical study designed to assess the safety and performance of the Epicare fractional nano-thulium (Tm:YAP 1938 nm) laser system for the treatment of…
- Trial name
- NCT07114562
- Testing
- Epicare
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laser team Ltd
Periorbital Wrinkles
Reducing Wrinkles Around the Eyes Using the Ulthera® System
The purpose of this prospective, multi-center, single treatment study is to evaluate the clinical outcomes associated with the non-invasive treatment to reduce wrinkles around the eyes utilizing the Ulthera® System to deliver…
- Trial name
- NCT01368900
- Testing
- Ulthera® System treatment
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Periorbital Wrinkles
Safety and Efficacy of XP200 Radiofrequency Treatment of Wrinkles
To evaluate the wrinkle-reducing effects of 3.25-MHz radiofrequency (RF) energy delivered in 4 weekly applications to human periorbital skin area by grating pre- and 90-days post treatment photographs on the Fitzpatrick Wrinkle…
- Trial name
- NCT01795417
- Testing
- RF XP200, XP200 RF device
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Skin Resurfacing
A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing
This study is a prospective, post-marketing (Phase 4) non-registrational single-arm, open-label, multicenter study.
- Trial name
- NCT07214272
- Testing
- Fraxel® FTX Laser System
- Where
- 5 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Wrinkle
A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser
This study is designed to explore the safety and the effectiveness of the Tixel device. This device performs fractional treatment of the skin by applying thermal (heat) energy to the skin.
- Trial name
- NCT03454672
- Testing
- Tixel, Laser
- Where
- 2 sites in United States, Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dark Eye Circles (Periorbital Hyperpigmentation)
Vitamin K2 (35) (MK-7) Reduces Dark Eye Circles: a Mechanistic and Human Efficacy Study
The goal of this clinical trial is to learn if an eye cream containing 0.05% Vitamin K2 (35) (MK-7) works to reduce vascular-type dark eye circles in women aged 20-60 years.
- Trial name
- NCT07881367
- Testing
- MK-7 Eye Cream
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nanjing Ascend Biotech Technology Co., Ltd.
Periorbital Edema
Energy-Based Lower Eyelid Rejuvenation - Proof of Concept for InMode AccuTite With or Without Morpheus8
1. To establish clinical efficacy, safety and patient satisfaction of reducing lower eyelid convexities or "bags" and/or malar crescents (festoons) with catheter-based injectable RF (InMode AccuTite) and variable depth Fractional…
- Trial name
- NCT04103619
- Testing
- AccuTite, AccuTite + Morpheus 8
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Wrinkle
Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
The core objective of this study is to validate the safe and efficacious application of the AcusMu microneedle patch (FMD WK) to enhance the appearance of periorbital wrinkle
- Trial name
- NCT06158867
- Testing
- FMD WK
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AcusMu Medtech Co., Ltd.
Wrinkled Structure
A Confirmatory Study for Evaluation of the Treatment by the Celluma3 of Periorbital Wrinkles
The primary objective of this study is to confirm the safe and effective use of the Celluma3 for the reduction in the appearance of periorbital wrinkles.
- Trial name
- NCT02543970
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- BioPhotas