Clinical trials: Peripheral Arterial
Peripheral Arterial Disease, Peripheral Artery Disease
Dietary Nitrate Supplementation and Thermoregulation
This is a double-blinded, randomized, crossover design study to assess the effects of dietary nitrate supplementation (beetroot juice) on peripheral artery disease (PAD) patients (ages 50-85) diagnosed with Fontaine stage I or II…
- Trial name
- NCT03506646
- Testing
- Beet root juice
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Nebraska
Symptomatic Peripheral Artery Disease With Femoropopliteal Lesions, Moderate or Severe Claudication (Rutherford Category 2 or 3)
Korean Multicenter Registry of ELUVIA Stent for Femoropopliteal Artery Disease (K-ELUVIA Registry)
Prospective, multi-center single-arm observational study A total of 100 subjects with femoropopliteal artery disease who meet all inclusion and exclusion criteria will be included.
- Conditions
- Symptomatic Peripheral Artery Disease With Femoropopliteal Lesions, Moderate or Severe Claudication (Rutherford Category 2 or 3), Critical Limb Ischemia (Rutherford Category 4 or 5)
- Trial name
- NCT03505931
- Testing
- Implantation of Eluvia stent
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Peripheral Artery Disease, Vascular Disease
Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients
The purpose of the study is to assess the effect of blood flow to the heart when subjects are treated with ticagrelor (Brilinta) or clopidogrel (antiplatelet drugs that stop the blood from clumping together) in patients with…
- Conditions
- Peripheral Artery Disease, Vascular Disease, Arterial Occlusion Disease, Intermittent Claudication
- Trial name
- PAD (NCT02121288)
- Testing
- Ticagrelor, clopidogrel
- Sponsor
- AstraZeneca
Extracranial Atherosclerosis
Images in Extracranial Artery Stenosis
The goals of this trial are: 1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis.
- Trial name
- NCT00173927
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Lumbar Spinal Stenosis, Intermittent Claudication
Efficacy of Acupuncture for Lumbar Spinal Stenosis
Degenerative lumbar spinal stenosis (DLSS) is a condition which there is narrowing space of sagittal diameter of spinal canal or nerve root canal for spinal nerve or cauda equina secondary to degenerative changes.
- Trial name
- NCT03784729
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Peripheral Arterial Disease, Atherosclerosis Obliterans
Comparison of 3 Ultrasonic Techniques for Measuring the Systolic Pressure Index
Continuous Doppler ankle brachial index (ABI) is the gold standard for screening and monitoring of peripheral arterial disease (PAD) but is no longer carried out in clinical practice.
- Conditions
- Peripheral Arterial Disease, Atherosclerosis Obliterans, Atherosclerosis Right Leg, Atherosclerosis Left Leg
- Trial name
- ABIPULSE (NCT04440072)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Peripheral Arterial Disease
The Cre8™ BTK Post Market Clinical Follow-up Study
Cre8™ BTK is a CE marked drug eluting stent, integrally coated with i-Carbofilm, loaded with formulated Sirolimus for the treatment of infrapopliteal peripheral artery disease.
- Trial name
- NCT05616156
- Testing
- Cre8™ BTK
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- CID S.p.A.
PAD
Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs.
- Trial name
- EDPAD (NCT05345431)
- Testing
- endovascular denervation, PTA
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Zhongda Hospital
Endothelial Dysfunction
Endothelial Function in Human Arteries
Up to 30 patients with lower extremity disease scheduled to undergo diagnostic angiography will undergo baseline bloodwork and IVUS (intravascular ultrasound), followed by dosing with L-arginine to assess changes in endothelial…
- Trial name
- NCT00848302
- Testing
- L-arginine
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Diabetic Foot, Peripheral Arterial Disease
Hemodynamic Effects of Intramuscular PDA-002 in Subjects Who Have Diabetic Foot Ulcer With Peripheral Arterial Disease
Study PDA-002-DFU-003 is a Phase 2, multicenter, randomized, double blind, placebo-controlled, dose range finding study in subjects who have diabetic foot ulcer (DFU) with peripheral arterial disease (PAD).
- Trial name
- NCT02460081
- Testing
- PDA-002
- Where
- United States
- Sponsor
- Celularity Incorporated
Peripheral Artery Disease
Comparative Pharmacokinetic Study Between Two Extended-Release Cilostazol Formulations in Korea
This is a randomized, open-label, multiple-dose, two-sequence, two-period crossover study to to compare the safety/tolerability and pharmacokinetics between Pletaal SR Cap. and Cilostan CR Tab. in healthy volunteers
- Trial name
- NCT03524963
- Testing
- Cilostan CR Tab., Pletaal SR Cap.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Peripheral Arterial Disease, Diabetes Mellitus
Cell Therapy for Peripheral Arterial Disease and Diabetes
This is a randomized controlled trial with blinding (for the observer who evaluates treatment goals). With two groups to study. A group of patients with conventional therapy for the treatment of PAD (Platelet antiaggregant…
- Trial name
- NCT03635970
- Testing
- celular therapy
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Intermittent Claudication, Ischemia Vascular
Ischemic Preconditioning Claudication Study
This study proposes ischemic preconditioning (IPC) as a novel intervention to improve walking distance in patients with intermittent claudication.
- Conditions
- Intermittent Claudication, Ischemia Vascular, Peripheral Arterial Disease, Peripheral Vascular Disease
- Trial name
- NCT03511157
- Testing
- Ischemic Preconditioning, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical College of Wisconsin
Sepsis, Septic Shock
Cardiovascular Phenotypes in Sepsis
This prospective observational study will investigate cardiovascular phenotypes in adults with sepsis and hemodynamic instability.
- Conditions
- Sepsis, Septic Shock, Cardiovascular Dysfunction, Microcirculatory Dysfunction
- Trial name
- CaPS (NCT07442032)
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Intermittent Claudication
Supervised Exercise-based Rehabilitation for People With Intermittent Claudication in Denmark
The goal of this project is to implement a protocol for a supervised exercise therapy intervention including smoking cessation in the municipalities in region Zealand in Denmark.
- Trial name
- StRiDE (NCT06299956)
- Testing
- Supervised exercise therapy
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Slagelse Hospital
Peripheral Arterial Disease(PAD)
Effects of Virtual Reality Exercises on Individuals With Peripheral Artery Disease
The aim of this study is to investigate the effects of virtual reality exercises on lower extremity skin temperature, arterial stiffness, gait parameters and enjoyment of exercise in individuals with peripheral arterial disease.
- Trial name
- NCT06618131
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Dokuz Eylul University
Atherosclerotic Cardiovascular Disease
In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease
Study CKJX839B1FR01 in an In silico trial to predict the efficacy of Inclisiran therapy on major adverse cardiovascular events (MACE) and cardiovascular (CV) death in virtual patients with atherosclerotic cardiovascular disease…
- Trial name
- SIRIUS (NCT05974345)
- Testing
- Inclisiran sodium, Ezetimibe, Evolocumab
- Where
- France
- Volunteers
- 204,691 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus, Diabetic Foot
Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia
Diabetic foot syndrome (DFS) is a disease caused by neurogenic (concerning the nervous system), vascular, mechanic and metabolic factors, which are further complicated by an impairment of the immune system and a corresponding…
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Foot, Critical Limb Ischemia
- Trial name
- August-1 (NCT01599442)
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- GWT-TUD GmbH
Peripheral Arterial Disease
Long-term Pleiotropic Effect of Statins in Patients With Peripheral Arterial Disease
The purpose of this study is to determine the long-term effects of statins, atorvastatin, upon Nitric Oxide, as an endothelial function assessment, and C-Reactive Protein, an inflammatory marker, levels in patients with…
- Trial name
- NCT01041729
- Testing
- Atorvastatin, Standard Medical Treatment
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Getafe
Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department
The purpose of this clinical trial is to determine the best initial non-invasive respiratory support (NIRS) strategy for adults who present to the emergency department with acute hypoxemic respiratory failure, a condition in…
- Trial name
- WINDSURFER (NCT07558265)
- Testing
- Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ohio State University
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