Clinical trials: Peripheral Arterial
Arterial Stiffness, Magnetic Field Exposure
Assessing Impacts of Static Magnetic Fields on Peripheral Pulses and Skin Blood Flow
The purpose of this research study is to investigate and determine the effects of static magnetic fields produced by a small magnet on peripheral pulses and skin blood flow.
- Conditions
- Arterial Stiffness, Magnetic Field Exposure, Peripheral Arterial Disease
- Trial name
- NCT04539704
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Peripheral Arterial Disease
Creatine Use and Muscle Stretching in Peripheral Artery Disease
To utilize near-infrared spectroscopy to investigate if the research device, which induces muscle stretching, and creatine loading impact submaximal exercise performance in aged and PAD patients.
- Trial name
- NCT04471792
- Testing
- Creatine monohydrate, Cellulose
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Florida State University
Obstructive Coronary Artery Disease
Coronary Revascularization Versus Conservative Therapy in Patients With Treated Critical Limb Ischemia
The objective of the INCORPORATE trial is to evaluate whether an intentional invasive strategy with ischemia targeted, reasonably complete coronary revascularization and optimal medical therapy is superior as compared to a…
- Trial name
- INCORPORATE (NCT03712644)
- Testing
- FFR-guided coronary revascularization
- Where
- 2 sites in Austria, Hungary
- Volunteers
- 650 people
- Sponsor
- Medical University of Graz
Tumor, Solid, Neuroblastic Tumors
Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors
Neuroblastic tumors (NBTs) develop from neural crest cells that give rise to the sympathetic nervous system. They include neuroblastomas, ganglioneuroblastomas, and ganglioneuromas.
- Conditions
- Tumor, Solid, Neuroblastic Tumors, Neuroblastoma
- Trial name
- AKA-NBL (NCT06798532)
- Testing
- Collection of data from the patient's medical file.
- Where
- 27 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Limb-Threatening Ischemia
Esprit BTK Post-Approval Study
The Esprit BTK PAS is a prospective, single-arm, multi-center observational study to assess the continued safety and effectiveness of the Esprit™ BTK Everolimus Eluting Resorbable Scaffold System under commercial use, in patients…
- Trial name
- EspritBTKPAS (NCT06656364)
- Testing
- Esprit BTK System
- Where
- 39 sites in United States, Hong Kong and 2 more
- Volunteers
- 200 people
- Sponsor
- Abbott Medical Devices
Peripheral Artery Disease, Intermittent Claudication
Improving Mobility After Revascularization in Peripheral Artery Disease
Lower extremity revascularization combined with supervised exercise significantly improves walking performance compared to revascularization alone in people who have PAD without limb threatening ischemia.
- Conditions
- Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation
- Trial name
- IMPACT PAD (NCT06686121)
- Testing
- Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control
- Where
- 8 sites in United States
- Volunteers
- 386 people
- Sponsor
- Northwestern University
Peripheral Arterial Disease, Vascular Surgery
Remote Ischemic Preconditioning Prior to Vascular Surgery
The investigators have previously shown that elective vascular surgery is a high-risk operation with an anticipated risk of either death or heart attack of 15%.
- Trial name
- CRIPES (NCT01558596)
- Testing
- Preconditioning, Control
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Peripheral Arterial Disease, Critical Limb Ischemia
Swedish Drug-elution Trial in Peripheral Arterial Disease
Peripheral arterial disease (PAD) causes reduced blood flow to the lower limb(s) due to stenosis or occlusion in the supplying arteries.
- Conditions
- Peripheral Arterial Disease, Critical Limb Ischemia, Intermittent Claudication
- Trial name
- SWEDEPAD (NCT02051088)
- Testing
- Revascularization with drug-eluting technology, Revascularization without drug-eluting technology, drug-coated balloons and/or drug-eluting stents
- Where
- Sweden
- Volunteers
- 3,556 people
- Sponsor
- Sahlgrenska University Hospital
Liver Cirrhosis
Mesenchymal Stem Cells Transplantation for Liver Cirrhosis Due to HCV Hepatitis
In this study, investigators aimed to transplant autologous, adipose tissue derived mesenchymal stem cells to the patients with liver cirrhosis due to HCV.
- Trial name
- NCT02705742
- Testing
- Mesenchymal Stem Cells
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Peripheral Arterial Disease
Thrombospondin-4 Levels and Peripheral Arterial Disease in Hemodialysis Patients
Background: Peripheral arterial disease (PAD) a condition characterized by atherosclerotic occlusive disease of the lower extremities is commonly observed in patients with chronic kidney disease (CKD) patients, particularly those…
- Trial name
- NCT04735562
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Peripheral Arterial Disease
Evaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arterial Disease
The goal of this clinical trial is to study the safety and tolerability of Etrinabdione in adult patients with peripheral arterial disease. It will also learn about the preliminary efficacy of Etrinabdione.
- Trial name
- CLAUDIA (NCT06774040)
- Testing
- Etribnabdione 25 mg BID, Etribnabdione 50 mg BID
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- VivaCell Biotechnology España
Peripheral Arterial Disease, Peripheral Bypass Surgery
Pilot Study to Asses the Function and Patency of Polyester-Coated Composite Bypasses From Autologous Varicose Veins
If patients need to undergo bypass surgery, either an autologous vein can be used as bypass or, if there are no suitable veins are available, a prosthetic graft can be implanted.
- Conditions
- Peripheral Arterial Disease, Peripheral Bypass Surgery, Bypass From Autologous Varicose Vein, External Graft Support
- Trial name
- PROVENA (NCT00460291)
- Testing
- Implantation of the ProVena vein graft during bypass surgery
- Where
- 11 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Critical Limb Ischemia, Ischemic Ulcers
Stem Cells for Treating Critical Ischemia
Collection of bone marrow blood Selection of mononuclear cells dilution with albumin injection into the calf muscles through 40 shots
- Trial name
- NCT00488020
- Testing
- stem cells transplant
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Instituto de Molestias Cardiovasculares
Peripheral Arterial Disease
Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty
The SirPAD trial is an academic, investigator-initiated, single-center, randomized, non-inferiority, open-label clinical trial investigating whether the use of sirolimus-coated balloon catheters in patients with peripheral artery…
- Trial name
- NCT04238546
- Testing
- sirolimus-coated balloon catheter, uncoated balloon catheter
- Where
- 2 sites in Switzerland
- Volunteers
- 1,200 people
- Sponsor
- Nils Kucher
Femoropopliteal Artery Occlusion
Outcome of Endovascular Therapies in Chronic Femoropopliteal Occlusive Disease With Severe Calcification
This study is a prospective, multicenter, real world, observational study, which aims at evaluating the safety, efficacy and economic cost of endovascular treatments for endovascular therapies in chronic femoropopliteal occlusive…
- Trial name
- NCT04716361
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Critical Limb Ischemia
SCOPE CLI (Shifting Care and Outcomes for Patients With Endangered Limbs - Critical Limb Ischemia)
Given the importance of understanding CLI patients' outcomes and existing gaps in knowledge, there is a pressing need to collect observational data on treatment patterns, adherence to performance measures, and outcomes that are…
- Trial name
- SCOPE CLI (NCT03171259)
- Testing
- care as usual
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Saint Luke's Health System
Peripheral Arterial Disease, Femoropopliteal Stenosis
PMCF Study for Peripheral Arteries Above the Knee (ATK)
The rationale of this study is to confirm and support the clinical safety and performance of the products in a real-word population of 350 patients who underwent an endovascular intervention within standard-of-care (SOC) of the…
- Conditions
- Peripheral Arterial Disease, Femoropopliteal Stenosis, Angiopathy, Peripheral
- Trial name
- NCT05312580
- Where
- 9 sites in Austria, France and 1 more
- Volunteers
- 387 people
- Sponsor
- Cordis US Corp.
Intermittent Claudication
Assess the Safety and Effectiveness of Once Daily PMR Compared to Twice Daily Pletaal® in Patients With Intermittent Claudication
The study is designed to compare the efficacy and safety of once daily PMR treatment with twice daily Pletaal® treatment in patients with intermittent claudication caused by peripheral arterial disease and are currently treated…
- Trial name
- NCT06886620
- Testing
- Cilostazol 200 mg, Cilostazol 100 mg
- Where
- 5 sites in Taiwan
- Volunteers
- 14 people
- Sponsor
- Genovate Biotechnology Co., Ltd.,
Coronary Artery Disease (CAD), Peripheral Arterial Disease (PAD)
Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk
Registry to describe the impact in terms of effectiveness and safety of the combination treatment of rivaroxaban 2.5 mg twice daily with aspirin on clinical outcomes and practices in a real-life Dutch patient population that are…
- Trial name
- NCT04753372
- Testing
- Rivaroxaban 2.5 MG [Xarelto]
- Where
- 12 sites in Netherlands
- Volunteers
- 645 people
- Sponsor
- Maatschap Cardiologie Zwolle
Diabetic Foot, Diabetes
Predictors of Skin Temperature, Plantar Pressure and Ulceration in Diabetic Foot Patients.
Diabetes is a chronic disease with increasing prevalence worldwide with a high burden to individuals and the society and it is expected to be the 7th leading cause of death in 2030.
- Trial name
- NCT03254095
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
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