Clinical trials: Peripheral Arterial Vascular Occlusion
Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication
Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients
Acute compartment syndrome (ACS) is a surgical emergency that can develop in patients on extracorporeal membrane oxygenation (ECMO).
- Conditions
- Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication, Limb Ischemia, Limb Ischemia, Critical
- Trial name
- VA-ECMO (NCT05830721)
- Testing
- MY01 + Standard of Care, 14-Gauge Slit Catheter + Standard of Care, Standard of Care
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Peripheral Artery Disease
VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication.
Peripheral Arterial Disease (PAD) is a highly debilitating disease that affects 202 million people around the world and about 7 million people in France. Morbi-mortality from cardiovascular events is increased in this population.
- Trial name
- VIRTUOSE (NCT03686306)
- Testing
- Sildenafil
- Where
- 11 sites in France
- Volunteers
- 106 people
- Sponsor
- Rennes University Hospital
Peripheral Artery Disease, Coronary Artery Disease
Routine Coronary Catheterization in Low Extremity Artery Disease Undergoing Percutaneous Transluminal Angioplasty
1. The prevalence of significant and complex obstructive coronary artery disease (CAD) is high in patients who have low extremity artery disease (LEAD). 2.
- Trial name
- PIROUETTEPTA (NCT02169258)
- Testing
- Systemic Strategy
- Where
- Taiwan
- Volunteers
- 700 people
- Sponsor
- National Cheng-Kung University Hospital
Peripheral Artery Disease, Intermittent Claudication
Patients With Intermittent Claudication Injected With ALDH Bright Cells
The purpose of this study is to find out if aldehyde dehydrogenase bright (ALDHbr) cells taken from a patient's bone marrow can be placed safely, via intramuscular injections, into their affected calf and lower thigh muscles and…
- Trial name
- PACE (NCT01774097)
- Testing
- ALD-301
- Where
- 9 sites in United States
- Volunteers
- 82 people
- Sponsor
- The University of Texas Health Science Center, Houston
Critical Limb Ischemia
Umbilical Cord Artery-derived Perivascular Stem Cells for the Critical Limb Ischemia Therapy
This clinical trial included 2 periods. During the first period, it was a single arm study to explore the safety of umbilical cord artery-derived stem cells (UCA-PSCs) in the treatment of patients with critical limb ischemia…
- Trial name
- NCT06174597
- Testing
- UCA-PSCs/bFGF or bFGF Intramuscular injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing University
Lower Extremity Artery Disease
Validation of a Magnetic Sensor in Arterial Flow Recording, Compared With the Reference Method, at Various Peripheral Arterial Sites
The measurement of magnetic fields emitted by cardiac activity has already been studied in magneto-cardiography. To date, however, this technology has never been evaluated in the peripheral circulation.
- Trial name
- COMADO (NCT06274697)
- Testing
- Evaluation by magnetic sensor
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Montpellier
Peripheral Artery Disease
Structured Home-based Exercise Versus Walking Advice in Claudication Patients: a Randomized-controlled Trial
A recent position paper calls for effective home-based exercise program for patients with peripheral artery disease (PAD) and claudication to be implemented in real-world care.
- Trial name
- NCT04751890
- Testing
- Structured home-based exercise, Walking advice
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- University Hospital of Ferrara
Peripheral Vascular Disease
Trial to Evaluate the Safety & Efficacy of the Omnilink Elite™ Peripheral Balloon-Expandable Stent System in Subjects With Atherosclerotic de Novo or Restenotic Lesions in the Native Common Iliac Artery and/or Native External Iliac Artery
To determine the safety and efficacy of the Omnilink Elite™ Peripheral Balloon-Expandable Stent System in subjects with atherosclerotic de novo or restenotic lesions in the native common iliac artery and/or native external iliac…
- Trial name
- MOBILITY OE (NCT01396525)
- Testing
- Omnilink Elite™ Peripheral Balloon-Expandable Stent System
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease, Diabetic Foot Ulcer
Study of PDA-002 in Subjects With Peripheral Arterial Disease and Diabetic Foot Ulcers
This Phase 1, multicenter, open-label, dose-escalation study evaluated the safety and tolerability of intramuscular administration of PDA-002 (human placenta-derived cells) in subjects with peripheral arterial disease (PAD) and…
- Trial name
- NCT01859117
- Testing
- PDA-002
- Where
- 12 sites in United States
- Volunteers
- 15 people
- Sponsor
- Celularity Incorporated
Peripheral Arterial Disease
Community-Based Detection and Treatment of Peripheral Arterial Disease in Hispanics.
Peripheral Arterial Disease (PAD) is a highly prevalent public health problem that results from progressive atherosclerosis of arteries in the lower extremities.
- Trial name
- NCT01440634
- Testing
- Supervised exercise Program
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- University of Texas Southwestern Medical Center
Peripheral Arterial Disease (PAD), Intermittent Claudication
Home-based Exercise Therapy for Patients With PAD
Cardiovascular disease represents a considerable economic burden to society and effective preventive measures are necessary. Patients with peripheral arterial disease (PAD) have a severe impairment of functional ability, namely…
- Trial name
- WalkingPAD (NCT04749732)
- Testing
- WalkingPad plus Psychological Intervention - PsyWPad Group, WalkingPad plus Virtual Assistant - CyberWPad Group, WalkingPad group - Paper WPad Group
- Where
- Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar do Porto
Arteriovenous Malformation, Gastrointestinal Bleed
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
The purpose of the Case-Specific Health Care Professional (HCP) Clinical Survey for Concerto Versa™ Detachable Coils, also known as the Concerto Versa HCP Clinical Assessment, is to collect early clinical data from HCPs to assess…
- Conditions
- Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
- Trial name
- NCT07639853
- Testing
- Concerto Versa™ Detachable Coils
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medtronic Endovascular
Peripheral Artery Disease
Clinical Implications of Peripheral Plaque Morphology
Peripheral Artery Disease involves a buildup of fatty deposits (plaque) within blood vessels that can restrict blood flow. Patients who have PAD and claudication (pain in legs during exercise due to poor blood circulation) may be…
- Trial name
- NCT00578422
- Testing
- Ivus (Intravascular Ultrasound) of Amputation Specimens, IVUS (Intravascular Ultrasound)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- The Cleveland Clinic
Peripheral Arterial Disease
Chronic Total Occlusion Crossing With the Wildcat Catheter
This is a prospective, multi-center, non-randomized study of the Wildcat Catheter to cross a single femoropopliteal chronic total occlusion (CTO).
- Trial name
- CONNECT (NCT01174784)
- Testing
- Chronic TOtAl OcclusioN CrossiNg with thE WildCat CatheTer
- Where
- 15 sites in United States
- Volunteers
- 88 people
- Sponsor
- Avinger, Inc.
Peripheral Arterial Disease
The Biomimetic Stent and Vascular Functions Study
The aim of this IIT is to determine the potential improvement and impact of the BioMimics 3D Stent System in the SFA on local vascular function.
- Trial name
- NCT05447052
- Testing
- Bio-MIMICS 3D Stent, Innova Stent
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital, Essen
Peripheral Arterial Disease
Cardiopulmonary Exercise Test in Peripheral Arterial Disease
Aim: To determine whether the lactate threshold during CPET is influenced by the presence of haemodynamically significant PAD. Assumption: Correction of haemodynamically significant PAD results in an increased LT, measured by…
- Trial name
- NCT02657278
- Testing
- Arterial Revascularization surgery or Endovascular procedure
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Peripheral Vascular Disease
Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia
The purpose of this study is to assess the safety and feasibility of HBOC-201 in increasing adequate wound healing in patients with severe peripheral vascular disease who are undergoing lower limb amputation.
- Trial name
- NCT00300040
- Testing
- Hemoglobin glutamer 250 - bovine, 6% Hydroxyethylstarch
- Where
- 5 sites in South Africa, United Kingdom
- Volunteers
- 16 people
- Sponsor
- Biopure Corporation
Peripheral Arterial Disease
Development and Validation of the Modified Version of VascuQol Scale in Patients With Lower Extremity Peripheral Arterial Disease.
The purpose of this study is to assess the utility of the Modified version of VascuQol Scale as an effective biopsychosocial assessment tool for patients suffering from lower extremity peripheral arterial disease.
- Trial name
- NCT06223217
- Testing
- Surveys and Questionnaires
- Where
- China
- Volunteers
- 480 people
- Sponsor
- RenJi Hospital
Peripheral Arterial Disease
Ultrasound Evaluation of Lower Extremity Arteries After Topical Nitroglycerin Administration
There have not been any published studies showing the use of topical nitroglycerin on the dilatory effect on the posterior tibial or dorsalis pedis arteries.
- Trial name
- NCT04155476
- Testing
- Nitroglycerin Topical Product
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Deborah Heart and Lung Center
Critical Limb Ischemia
Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia
The purpose of this study is to evaluate the safety and efficacy of the concentrated autologous bone marrow derived stem cells for the treatment of Critical Limb Ischemia patients.
- Trial name
- NCT01472289
- Testing
- Autologous Bone Marrow Mononuclear cells (BMMNCs)
- Where
- India
- Volunteers
- 17 people
- Sponsor
- TotipotentSC Scientific Product Pvt. Ltd.
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