Clinical trials: Peripheral Nerve Disorder
Postherpetic Neuralgia ( PHN ), Ultrasound Guided, Block, Ultrasound Guided Injection
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study
Postherpetic neuralgia (PHN) is a chronic pain syndrome that can be resistant to treatment, leading to physical and social disability, psychological disturbances, and potentially persisting for years .
- Trial name
- pain (NCT07067892)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postherpetic Neuralgia
A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
The purpose of this trial is to determine if XPF-002 is safe and effective for the treatment of pain in subjects with Postherpetic Neuralgia
- Trial name
- XEN402 (NCT01195636)
- Testing
- XPF-002
- Where
- 24 sites in United States
- Volunteers
- 70 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Neurofibromatosis Type 1
PASS of Paediatric Patients Initiating Selumetinib
Neurofibromatosis type 1 (NF1) is a rare, autosomal dominant genetic disorder that is caused by germline mutations in the NF1 tumour suppressor gene, which encodes the tumour suppressor protein neurofibromin 1.
- Trial name
- NCT05388370
- Where
- 46 sites in Austria, France and 8 more
- Volunteers
- 124 people
- Sponsor
- AstraZeneca
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC
Metastatic Olfactory Neuroblastoma, Recurrent Olfactory Neuroblastoma
A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma
To learn if rivoceranib can help to control olfactory neuroblastoma. The safety of this drug in participants with olfactory neuroblastoma will also be studied.
- Trial name
- NCT06308575
- Testing
- Rivoceranib
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Carpal Tunnel Syndrome (CTS)
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the effectiveness of rest splints and high-intensity laser therapy(HILT) added to physical therapy programs for patients with carpal tunnel syndrome in terms of pain, function, nerve conduction…
- Trial name
- NCT07294157
- Testing
- Rest splint group, high-intensity laser therapy (HILT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Afyonkarahisar Health Sciences University
Brain Tumor, Central Nervous System Tumor
Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so that they stop growing or die. bone marrow transplantation and peripheral stem cell transplantation may allow the doctor to give higher…
- Trial name
- NCT00002594
- Testing
- Sargramostim, cyclophosphamide, melphalan
- Where
- 118 sites in United States, Australia and 4 more
- Volunteers
- 31 people
- Sponsor
- Children's Oncology Group
Neuropathic Pain
Balance and Gait on Neuropathic Pain Due to Lumbar Disc Degeneration
Chronic lumbar neuropathic pain, characterized by pain, numbness, tingling and muscle weakness in the lower extremities, is one of the most common neuropathic pain syndromes.
- Trial name
- NCT05223439
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Peripheral Neuropathy, HIV Infections
Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy
To evaluate the safety and efficacy of pregabalin in reducing neuropathic pain associated with HIV neuropathy
- Trial name
- NCT00264875
- Testing
- pregabalin
- Where
- 37 sites in United States, Puerto Rico
- Volunteers
- 220 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathic Pain
A High Frequency Spinal Cord Stimulation PET-CT Scan Study
This study aims to investigate the clinical response to Spinal Cord Stimulation frequency parameters: 40Hz, 4000Hz and 10000Hz and explore the brain imaging changes using PET-CT scans.
- Trial name
- NCT03716557
- Testing
- Spinal Cord Stimulation 4000Hz, Spinal Cord Stimulation 10000Hz, Spinal Cord Stimulation 40Hz
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Barts & The London NHS Trust
Carpal Tunnel
Clinical Outcomes of USCTR vs. mOCTR
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and affects 3-6% of adults in the United States.
- Trial name
- NCT04504019
- Testing
- USCTR, mOCTR
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Neuroblastoma, Medulloblastoma
Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer
The purpose of this study is to test the feasibility (ability to be done) of experimental technologies to determine a tumor's molecular makeup (gene expression profile) and mutations.
- Conditions
- Neuroblastoma, Medulloblastoma, Brain Tumors, Rare Tumors
- Trial name
- NCT01802567
- Testing
- Guided Therapy- Pediatric Gene Analysis Platform
- Where
- 13 sites in United States
- Volunteers
- 52 people
- Sponsor
- Giselle Sholler
Vestibular Schwannoma
Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging
Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging
- Trial name
- NCT03097822
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Neuropathic Pain
The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain
This study will test whether treatment with N-acetyl-L-cysteine (NAC) is safe and decreases pain in patients with chronic neuropathic pain.
- Trial name
- NCT01840345
- Testing
- N-acetyl-l-cysteine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Virginia Commonwealth University
Cervical Radiculopathy
Thoracic Manipulation in Patients With Cervical Radiculopathy
Hypothesis: The group of Cervical Radiculopathy patients receiving thoracic thrust manipulation will demonstrate immediate and short term significant clinically important changes in outcomes when compared to the sham manipulation…
- Trial name
- NCT01495728
- Testing
- Thrust Manipulation - Thoracic Spine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spine and Sport, Georgia
Migraine
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief.
- Trial name
- NCT06016465
- Testing
- Dexamethasone Oral
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
To Prevent Scar Formation for Patients Underwent Surgery
The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery
The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.
- Trial name
- NCT05017467
- Testing
- undefinedCentella Asiatica Extract
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mustafa Balevi,MD
Diabetic Neuropathies, Diabetes Mellitus
Efficacy and Safety of the Combination of Ten Elements for 6 Months in Patients With Diabetic Neuropathy : A Pilot Study
To investigate the efficacy of Superoxide Dismutase (SOD, 70 UI), Palmitoylethanolamide (PEA, 300 mg) Alpha Lipoic Acid (ALA, 300 mg), vitamins B6 (1.5 mg), B1 (1.1 mg), B12 (2.5 mcg), E (7.5 mg), Nicotinamide (9 mg) and minerals…
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Dietary Supplement
- Trial name
- NCT05984771
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Painful Diabetic Neuropathy
Functional Magnetic Resonance Imaging of Brain Activity in Patients With Painful Diabetic Neuropathy
Patients with painful diabetic neuropathy (PDN) often combine with anxiety and depression. However, the pathogenesis of PDN is unclear, especially the mechanism associated with central nervous system.
- Trial name
- NCT03700502
- Testing
- resting-state functional Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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