Clinical trials: Peripheral Nerve Disorder
Pilomyxoid Astrocytoma, Pilocytic Astrocytoma
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
This is a study to determine the safety and efficacy of the drug, mebendazole, when used in combination with standard chemotherapy drugs for the treatment of pediatric brain tumors.
- Conditions
- Pilomyxoid Astrocytoma, Pilocytic Astrocytoma, Glioma, Astrocytic, Optic Nerve Glioma
- Trial name
- NCT01837862
- Testing
- Mebendazole, Vincristine, Carboplatin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Julie Krystal
Carpal Tunnel Syndrome
Effect of Kinesiotaping and Night Splinting in Patients With Carpal Tunnel Syndome
Carpal tunnel syndrome (CTS) which is defined as a symptomatic compression neuropathy of the median nerve at the level of the wrist.
- Trial name
- NCT04993703
- Testing
- Kinesiotaping, Night Splinting, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Lumbar Radiculopathy
The Aim of Study is to Identify the Predictive Factors for the Success of Transforaminal Epidural Injection in Treatment of Patients with Lumbosacral Radiculopathy
the aim of the study is to identify predictive factors for the success of transforaminal epidural injection in the treatment of patients with lumbosacral radiculopathy
- Trial name
- NCT06795542
- Testing
- lumbosacral transforaminal epidural injection at the level of L4-5, L5-S1, or S1 neural foramina
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amr Mohamed Sedik
Chronic Inflammatory Demyelinating Polyneuropathy, Myasthenia Gravis
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
This study will have two Phases: Phase 1a and Phase 1b. The goals of this clinical study are to learn more about the study drug KITE-363, by evaluating its safety, tolerability and efficacy in participants with…
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy, Myasthenia Gravis, Multiple Sclerosis
- Trial name
- HERMOSA-2 (NCT07304154)
- Testing
- KITE-363, Fludarabine, Cyclophosphamide
- Where
- 10 sites in United States, Australia and 1 more
- Volunteers
- 57 people
- Sponsor
- Kite, A Gilead Company
Vestibular Schwannoma
Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma
A recent study by Plotkin et al. showed that bevacizumab (Avastin) treatment was followed by clinically meaningful hearing improvement, tumor-volume reduction, or both in some, but not all, patients with Vestibular Schwannoma…
- Trial name
- NCT01083966
- Testing
- Bevacizumab (Avastin)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Fatigue, Peripheral Neuropathy
LevineConservationModelandColorectalPatients
Colorectal cancer is one of the most common types of cancer in the world, ranking 3rd among cancers that cause death in men and women.
- Conditions
- Fatigue, Peripheral Neuropathy, Anxiety
- Trial name
- NCT06499129
- Testing
- Sensory ball, progressive relaxation exercise, training
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- KTO Karatay University
Regional Anesthesia Block, Regional Anesthesia
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)
Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus…
- Conditions
- Regional Anesthesia Block, Regional Anesthesia, Total Hip Replacement Surgery, Total Hip Arthroplasty \(THA\)
- Trial name
- Retro-PvF (NCT06342102)
- Testing
- PENG + LFCN block, FIC block
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale Edoardo Bassini
Diabetic Peripheral Neuropathy
Efficacy of Platelet Rich Plasma Injection in Diabetic Neuropathy
To evaluate the clinical efficacy and safety of peri-neural platelet rich plasma (PRP) injection in the treatment of diabetic peripheral neuropathy compared to traditional medical treatment.
- Trial name
- NCT03250403
- Testing
- PRP injection, traditional medical treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy
The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy in Gynaecological Cancer Patients
Objectives: To explore the feasibility and effectiveness of acupuncture on reducing Chemotherapy Induced Peripheral Neuropathy (CIPN) in gynaecological cancer patients who have received carboplatin and paclitaxel chemotherapy…
- Conditions
- Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy, Acupuncture
- Trial name
- AcuCIN (NCT06769061)
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- Karen Kar Loen CHAN
Foot Ulcer, Diabetes Mellitus
Efficacy Of CACIPLIQ20 On Diabetic Ulcers In Patients Wearing An Nonremovable, Windowed, Fiberglass Cast Boot
CACIPLIQ20 is a nanopolymer engineered to mimic glycosaminoglycans such as heparan sulfates. Glycosaminoglycans are implied 1) in the stabilization of the micro-environment of cells, known as extracellular matrix, by binding to…
- Conditions
- Foot Ulcer, Diabetes Mellitus, Diabetic Neuropathy
- Trial name
- DIAPLIQ (NCT01474473)
- Testing
- CACIPLIQ20 and Nonremovable, Windowed, Fiberglass Cast Boot
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Organ, Tissue, Regeneration, Repair and Replacement
Foot Drop
Innovative Shoe for People With Foot Drop
People with foot drop have an increased risk of tripping and falling, and this makes walking more difficult. Our colleagues at the Health Design Collective (HDC) have developed a shoe that aims to make it easier for people with…
- Trial name
- NCT06911151
- Testing
- innovative footwear
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen Margaret University
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Acupuncture and Compression for the Prevention of CIPN in Breast Cancer Patients
As a core component of comprehensive breast cancer treatment, chemotherapy frequently induces chemotherapy-induced peripheral neuropathy (CIPN), particularly with taxane-based agents.
- Trial name
- NCT07377279
- Testing
- Compression, Acupuncture, Compression combined with acupuncture
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
CIPN, Chemotherapy-induced Peripheral Neuropathy
Transauricular Vagus Nerve Stimulation in the Treatment of Chemotherapy-induced Peripheral Neuropathy
Chemotherapy induced peripheral neuropathy is common in tumor patients receiving chemotherapy. Nowaday, CIPN is mainly treated with drugs, but the therapeutic effect is not satisfactory.
- Trial name
- NCT05434403
- Testing
- Vagus nerve stimulation
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Peking University People's Hospital
Cubital Tunnel Syndrome
Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome
The objective of this study is to determine if nerve glide exercises in patients with cubital tunnel syndrome can improve pain, paraesthesias and reduce the need for future surgery.
- Trial name
- NCT03629470
- Testing
- Standard Conservative Treatment, Nerve Gliding Exercises
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Diabetic Neuropathy, Painful
A Study in Painful Diabetic Neuropathy
This study will investigate the efficacy of a combination treatment of duloxetine + pregabalin compared with the maximal dose of each drug in monotherapy, in patients with diabetic peripheral neuropathic pain (DPNP) who have not…
- Trial name
- COMBO-DN (NCT01089556)
- Testing
- Duloxetine, Pregabalin
- Where
- 54 sites in Australia, Canada and 14 more
- Volunteers
- 811 people
- Sponsor
- Eli Lilly and Company
Vestibular Schwannoma, Hearing Loss
Intraoperative EABR for Decision Making
In this study patients undergoing simultaneous translabyrinthine vestibular schwannoma resection and cochlear implantation are included. The goal of the study is to correlate the eABR results with postoperative hearing results.
- Trial name
- NCT03745560
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Christoph Arnoldner
Bladder Cancer, Breast Cancer
Chemotherapy in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I/II trial to study the effectiveness of oblimersen in treating patients who have solid tumors…
- Conditions
- Bladder Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer
- Trial name
- NCT00003103
- Testing
- oblimersen sodium, docetaxel
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Safety and Efficacy of JMKX000189 for Chemotherapy-Induced Peripheral Neuropathy
This Phase Ib clinical trial aims to evaluate the safety, tolerability, and preliminary efficacy of JMKX000189 tablets in participants with chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NCT07601386
- Testing
- JMKX000189
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Jeyou Pharmaceutical Co., Ltd.
Head and Neck Cancer, Mucositis Oral
GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
GM-CSF may protect normal cells from the side effects, such as mucositis, of radiation therapy and may help damaged tissue heal faster after radiation therapy.
- Conditions
- Head and Neck Cancer, Mucositis Oral, Radiation Toxicity, Tongue Cancer
- Trial name
- NCT00293462
- Testing
- sargramostim, oral salt and soda mouthwash
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Marilyn Dodd
Diabetic Neuropathies
Treatment for Diabetic Neuropathy Using Repetitive Transcranial Magnetic Stimulation
The aim of this study is to determine whether a 4-week treatment of repetitive transcranial magnetic stimulation (rTMS) can alleviate the symptoms of neuropathy in individuals with diabetic neuropathy.
- Trial name
- NCT06482827
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- McMaster University
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