Clinical trials: Peripheral Nerve Disorder
Malignancy
rTMS as a Treatment of Neuropathic Pain Secondary to Malignancy
The purpose of this study isto assess the efficacy of daily 10 sessions of rTMS over primary motor cortex in patients suffering from malignant neuropathic pain.
- Trial name
- NCT02078479
- Testing
- 20 Hz, 10 s, 10 trains with inter-train interval 30 s 2000 pulses , intensity 80% over hand area daily for 10 consecutive days (5 days/week).
- Volunteers
- 34 people
- Sponsor
- Assiut University
Chronic Pancreatitis
Pain and Chronic Pancreatitis - Clinical End Experimental Studies
The aim of the study is to investigate the effect of pregabalin in pain resulting from chronic pancreatitis. The effect will be investigated by means of questionnaires concerning the daily experience of pain and the general…
- Trial name
- CPP (NCT00755573)
- Testing
- Pregabalin
- Where
- 2 sites in Denmark, Netherlands
- Volunteers
- 64 people
- Sponsor
- Aalborg University Hospital
Morton's Neuroma
Comparison of Alcohol and Steroid Injection for Treating Morton's Neuroma
Interdigital neuroma is a painful forefoot disorder characterized by plantar pain and toe paresthesias thought to result from entrapment of the interdigital nerve by the overlying transverse metatarsal ligament.
- Trial name
- NCT00284583
- Testing
- Injection of Steroid into Foot, Injection of Alcohol into Foot, Injection of Lidocaine into Foot
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brown University
Cancer
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
RATIONALE: Giving donor natural killer cells to patients who have undergone donor bone marrow transplant may make the transplant work better and keep cancer cells from coming back.
- Trial name
- NCT00569283
- Testing
- therapeutic allogeneic lymphocytes
- Where
- 2 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Asan Medical Center
Peripheral Nerve Injuries
REINVENT Registry (Registry of the Nerve Gap Repair From Integra)
This is a prospective, multi-center, observational registry designed to evaluate two of Integra's collagen nerve gap repair products (NeuraGen® Nerve Guide and NeuraGen® 3D Nerve Guide Matrix).
- Trial name
- NCT05339594
- Testing
- NeuraGen, NeuraGen 3D
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Integra LifeSciences Corporation
Diabetus Mellitus, Diabetic Foot Ulcer
The Instant Effect of Whole Body Vibration in Diabetics
Overview of Diabetes and Its Complications: Diabetes is a chronic health issue that can lead to various complications, affecting human health negatively.
- Conditions
- Diabetus Mellitus, Diabetic Foot Ulcer, Diabetic Neuropathic Ulcer
- Trial name
- NCT06878651
- Testing
- The Whole Body Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Complex Regional Pain Syndromes
Evoked Fields After Median and Ulnar Stimulation
In order to be able to study the effects of evoked fields with magnetoencephalography (MEG) in two groups of patients, comparison is made with a group of healthy volunteers.
- Trial name
- NCT00217243
- Testing
- Evoked fields before and after a local block (Xylocaine)
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical Center Alkmaar
Pain Management, Sedation
The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty
The interaction of analgesia and sedation ot their effect on the prognosis of surgical patients still need to be elucidated.Currently, how to optimize intra-operative Analgesia and sedation to improve the prognosis of surgical…
- Conditions
- Pain Management, Sedation, Peripheral Nerve Block, Total Knee Arthroplasty
- Trial name
- NCT02576015
- Testing
- peri-operative continuous femoral nerve block with light sedation, post-operative continuous femoral nerve block, lidocaine
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Min Su
Degenerative Disc Disease
Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD
This study will evaluate the safety and effectiveness of a device called "Posterior Cervical Stabilization System or PCSS" when used along with posterior cervical fusion (PCF) in combination with anterior cervical discectomy and…
- Trial name
- FUSE (NCT04229017)
- Testing
- Anterior Cervical Discectomy and Fusion, Posterior Cervical Stabilization System (PCSS)
- Where
- 17 sites in United States
- Volunteers
- 236 people
- Sponsor
- Providence Medical Technology, Inc.
Brain and Central Nervous System Tumors, Lymphoma
Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
RATIONALE: Imetelstat sodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I clinical trial is studying the side effects and best dose of imetelstat sodium in…
- Conditions
- Brain and Central Nervous System Tumors, Lymphoma, Lymphoproliferative Disorder, Small Intestine Cancer
- Trial name
- NCT01273090
- Testing
- imetelstat sodium, laboratory biomarker analysis, pharmacological study
- Where
- 23 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- Children's Oncology Group
Sciatica, Intervertebral Disk Displacement
Manipulation or Microdiscectomy For Sciatica? A Prospective Randomized Controlled Trial.
The purpose of this study was to compare standardized chiropractic treatment (spinal manipulation) to back surgery (microdiscectomy) for patients with sciatica secondary to lumbar herniated disc refractory to medical management.
- Trial name
- NCT00415220
- Testing
- Spinal Manipulation, Microdiscectomy
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McMorland, Gordon, D.C.
Carpal Tunnel Syndrome (CTS)
Effect of Neural Mobilization on Carpal Tunnel Syndrome
The study group (G1) consisted of 15 patients treated by neural mobilization techniques targeting the median nerve, in addition to a selected physical therapy program including transcutaneous electrical nerve stimulation (TENS)…
- Trial name
- CTS (NCT07779096)
- Testing
- Neuromobilization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Injuries, Spinal Cord, Pain
Levetiracetam in Chronic Neuropathic Pain Following Spinal Cord Injury
Purpose: To evaluate the efficacy and safety of levetiracetam on chronic neuropathic pain after spinal cord injury, and to examine its effect on spasms and evoked pain.
- Trial name
- NCT00252954
- Testing
- Levetiracetam
- Where
- 3 sites in Denmark
- Volunteers
- 36 people
- Sponsor
- Danish Pain Research Center
Neuropathic Pain
Observational Study Aimed at Evaluating the Trend of Neuropathic Pain
The present study aims to evaluate the trend of neuropathic pain in patients treated with Peacetil for a period of two months. Neuropathic pain will me assessed through the Numeric Rating Scale (NRS) questionnaire score.
- Trial name
- NEURATIL (NCT06324123)
- Testing
- Peacetil
- Where
- 3 sites in Italy
- Volunteers
- 122 people
- Sponsor
- Istituto Auxologico Italiano
Carpal Tunnel Syndrome
Ibuprofen Arginine and Neural Mobilization Versus Ibuprofen Arginine in the Treatment of Carpal Tunnel Syndrome
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical ibuprofen arginine treatment will be compared to those produced by ibuprofen (only) treatment, in subjects who…
- Trial name
- NCT06778759
- Testing
- median nerve neural mobilization combined with oral ibuprofen arginine, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Diabetic Peripheral Neuropathy
Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus and is associated with sensory loss, impaired proprioception, balance deficits, and altered gait patterns, which significantly increase the risk…
- Trial name
- PNF-SR in DPN (NCT07380880)
- Testing
- Sensory Re-Education Program, Proprioceptive Neuromuscular Training
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Montiha Azeem
Knee Disease, Nerve Pain
Triple Injection Peri-sartorius (TIPS) Block
Comparison between the pain scores after total knee arthroplasty in patients receiving triple injection peri-sartorius (TIPS) block versus femoral nerve block (FNB)
- Trial name
- NCT05289427
- Testing
- ultrasound guided triple injection peri-sartorius block, Femoral Nerve Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Neuropathic Pain
Methylene Blue Intravenously and Chronic Neuropathic Pain
Aim of Investigation Methylene blue (MB) is a diaminophenothiazine with antioxidant, anti-inflammatory properties and with inhibitory effects on nitric oxide.
- Trial name
- NCT02303886
- Testing
- Methylene blue
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Carpal Tunnel Syndrome, Entrapment Neuropathy
Efficacy of Keyhole Approach to Carpal Tunnel Syndrome Under Ambulatory Strategy
Prospective controlled clinical trial in which a minimally invasive microsurgical approach was used following the keyhole principle in 55 patients and 65 hands under local anesthesia and ambulatory strategy.
- Trial name
- NCT03062722
- Testing
- keyhole approach
- Volunteers
- 55 people
- Sponsor
- Ivan Segura Duran
Diabetic Neuropathies
The Use of a Water Soluble Under the Tongue (Sublingual) CBD Tablet for Treating Pain Associated With Diabetic Peripheral Neuropathy
Use of Cannabidiol for the treatment of Diabetic Neuropathic Pain.
- Trial name
- NCT04088929
- Testing
- CBD
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pure Green
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