Clinical trials: Peripheral Nerve Injuries
Carpal Tunnel Syndrome
Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome
The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS).
- Trial name
- NCT06360510
- Testing
- %5 dextrose injection, betamethasone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Spinal Cord Injuries
Effect of Botulinum Toxin A on Detrusor Overactivity and Renal Function in Chronic Spinal Cord Injured Patients
To investigate the clinical effect of detrusor botulinum toxin A (BoNT-A) injection on neurogenic detrusor overactivity (NDO) and renal function and to compare the difference of expressions of sensory receptors and nerve growth…
- Trial name
- NCT01682603
- Testing
- Botulinum toxin A
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Carpal Tunnel Syndrome (CTS)
Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled Trial
Carpal Tunnel Syndrome (CTS) is the most common peripheral entrapment neuropathy, causing pain, paresthesia, and hand dysfunction due to median nerve compression at the wrist.
- Trial name
- PBM-CTS-RCT (NCT07714720)
- Testing
- Photobiomodulation (Low-Level Laser Therapy), Routine Physiotherapy Programme
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Brachial Plexus Neuropathies
Human Amniotic Membrane and Mesenchymal Stem Cells Composite
The purpose of this clinical trial is to investigate the utility of composite wrapping comprising human amniotic membrane and allogeneic adipose-derived mesenchymal stem cells (HAM-AdMSC) for augmentation of nerve transfer…
- Trial name
- BPI+MSC (NCT04654286)
- Testing
- Nerve transfer procedure, Nerve transfer with HAM-AdMSC composite wrapping
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Vestibular Schwannoma, Ototoxicity
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated…
- Trial name
- NCT05641441
- Testing
- Stereotactic radiosurgery
- Where
- Switzerland
- Volunteers
- 258 people
- Sponsor
- University Hospital, Geneva
Carpal Tunnel Syndrome, Entrapment Neuropathy
High Intensity Laser Therapy in Carpal Tunnel Syndrome
This research aims to investigate the effect of high-intensity laser therapy on pain, function, nerve conduction studies and grip strength in patients with idiopathic carpal tunnel syndrome.
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathy, Median Neuropathy, Musculoskeletal Diseases
- Trial name
- NCT04949373
- Testing
- High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Pain, Postoperative, Change; Circulatory
The Influence of Peripheral Nerve Blocks in Patients Undergoing Limb Orthopedic Surgery
To investigate pre-op peripheral nerve block in reducing peri-op IL-6 level and post-op pain
- Conditions
- Pain, Postoperative, Change; Circulatory, Surgical Injury
- Trial name
- NCT03913650
- Testing
- 0.25% bupivacaine
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Symptomatic Neuroma, Amputation
Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends
This pilot study evaluates the tolerability and feasibility of the Axoguard Large-Diameter Nerve Cap (sizes 5-7 mm) for protecting and preserving terminated nerve endings after limb trauma or amputation when immediate attention…
- Conditions
- Symptomatic Neuroma, Amputation, Chronic Nerve Pain
- Trial name
- REPOSE-XL℠ (NCT04865679)
- Testing
- Axoguard Nerve Cap®
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Axogen Corporation
Neuropathic Pain
Improving Functions in Veterans With Post-traumatic Peripheral Neuropathic Pain
The proposed study will set the foundation for future multi-center studies. To validate tMS as a non-contact and non-invasive pain treatment option for reducing pain in Veterans with PTP-NP and improving their overall functions.
- Trial name
- PTP-NP (NCT02979925)
- Testing
- Active Transcutaneous Magnetic Stimulation
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- VA Office of Research and Development
Carpal Tunnel Syndromes
The Role of the Cervical Spine in Carpal Tunnel Syndrome
This randomized clinical trial will investigate changes in hand function, active cervical range of motion and pinch grip force after the application of physical therapy in women with carpal tunnel syndrome (CTS).
- Trial name
- NCT02233660
- Testing
- Physical Therapy Group, Surgical Group
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome: Diagnosis and Treatment Trial
The Carpal Tunnel Syndrome Diagnosis and Treatment Trial is project #1 of the Multidisciplinary Clinical Research Center focused on upper extremity pain.
- Trial name
- NCT00032227
- Testing
- Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Washington