Clinical trials: Peripheral Nerve Injuries, open to volunteers
Carpal Tunnel Syndrome (CTS), Rheumatic Diseases
Comparison of Initial Treatment for Carpal Tunnel Syndrome Related to Rheumatic Diseases: Corticosteroid Injection Versus Nighttime Splinting
The aim of this study is to evaluate the effects of corticosteroid injection verses nighttime splinting as initial treatments on wrist function, quality of life, and sleep quality in patients with rheumatoid disease-related…
- Trial name
- NCT07042282
- Testing
- Nighttime Splinting, Corticosteroid Injection, Evaluation and Dynamic Adjustment
- Where
- 3 sites in China
- Volunteers
- 248 people
- Sponsor
- Yun Qian
Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
Carpal Tunnel Release Efficacy Trial
Background Carpal tunnel syndrome (CTS) is a prevalent condition that affects 2.7% of the population, especially women. It arises due to compression of the median nerve in the wrist and is linked to factors like diabetes…
- Trial name
- FOCUS (NCT06934187)
- Testing
- Carpal tunnel release
- Where
- Finland
- Volunteers
- 96 people
- Sponsor
- Kuopio University Hospital
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Peripheral Nerve Injuries, Median Nerve Injury
EMG-Triggered Electrical Stimulation After Median/Ulnar Nerve Repairs
Immobilization following median and/or ulnar nerve repairs results in strength loss in the wrist and finger extensor muscles. Given the critical importance of wrist extension for functional grip, this condition significantly…
- Conditions
- Peripheral Nerve Injuries, Median Nerve Injury, Ulnar Nerve Injury
- Trial name
- NCT07532499
- Testing
- EMG-triggered electrical stimulation, Conventional physiotherapy group
- Volunteers
- 26 people
- Sponsor
- Pamukkale University
Carpal Tunnel Syndrome
Combined Manual Therapy and Percutaneous Neuromodulation for Moderate Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and can cause pain, numbness, tingling, and functional impairment of the hand.
- Trial name
- MANUCTS (NCT07654621)
- Testing
- Combined Manual Therapy and Ultrasound-Guided Percutaneous Neuromodulation, Postsurgical Rehabilitation
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad Europea de Valencia
Carpal Tunnel Syndrome (CTS)
Clinical Efficiency Testing of Extracorporeal Radial and Focused Shock Wave Therapy in Patients With Mild to Moderate Carpal Tunnel Syndrome
The aim of the project is to test the efficacy of extracorporeal shock wave therapy (radial + focused) on clinical outcomes in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT06912893
- Testing
- radial shock wave therapy, focused shock wave therapy
- Volunteers
- 60 people
- Sponsor
- University Hospital St. Polten
Carpal Tunnel Syndrome (CTS), Muscle Stiffness
Immediate Effects of Paraffin Wax Therapy on Forearm and Hand Muscle Stiffness and Pain in Carpal Tunnel Syndrome
This randomized controlled trial aims to investigate the immediate effects of paraffin wax therapy on muscle stiffness and pain among patients diagnosed with Carpal Tunnel Syndrome (CTS).
- Trial name
- Paraffin-CTS (NCT07260448)
- Testing
- Paraffin Wax Therapy, Rest Period (No Treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Erzurum Technical University
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Carpal Tunnel Syndrome (CTS) Post-burn
Hand Function Outcome After the Application of Transfer Energy Capacitive and Resistive on Post-burn Patients Presented With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common entrapment neuropathy that can develop as a secondary complication following deep burns involving the hand or wrist.
- Trial name
- NCT07660328
- Testing
- Transfer Energy Capacitive and Resistive (TECAR) [ SMART TECAR }, Standard Hand Rehabilitation [ US }
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
CTS, Carpal Tunnel Syndrome (CTS)
Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
- Trial name
- NCT07653789
- Testing
- Combined Intervention Group, Neuromobilization Group, Tendon Gliding Exercise Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Carpal Tunnel Syndrome (CTS)
Changes in Sleep, Fatigue, Kinesiophobia, and Upper Extremity Function After Carpal Tunnel Release
Carpal tunnel syndrome can cause hand pain, numbness, weakness, sleep disturbance, fatigue, fear of movement, and difficulty performing daily activities.
- Trial name
- CTS-RECOVER (NCT07806071)
- Testing
- Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
Carpal Tunnel Syndrome
Carpal Arch Space Augmentation (CASA) Clinical Trial
This research proposes to evaluate the effectiveness of a novel device designed for the treatment of carpal tunnel syndrome. The device applies a small cyclic force to the wrist.
- Trial name
- CASA (NCT06208709)
- Testing
- carpal arch space augmentation (CASA), standard of care (SOC)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Arizona
Carpal Tunnel Syndrome
The Effect of Carpal Tunnel Syndrome Phenotyping on Response to Treatment
The aim of this study was to evaluate the effect of Carpal Tunnel Syndrome (CTS) phenotyping on responsiveness to clinical interventions in individuals with CTS.
- Trial name
- NCT07754708
- Testing
- Standard Rehabilitation Protocol
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Carpal Tunnel Syndrome
Comparison of the Efficacy of Ultrasound-Guided Corticosteroid Injection and Paraffin Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the efficacy of paraffin therapy, a physical therapy modality, and ultrasound-guided corticosteroid injection in the treatment of carpal tunnel syndrome, the most common entrapment neuropathy.
- Trial name
- NCT06658886
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Beylikduzu State Hospital
Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS)
124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome
This clinical trial will use the amyloid-binding radiotracer, 124I-evuzamitide, to potentially detect amyloid, in the heart and elsewhere, in patients who have a history of lumbar spinal stenosis and/or carpal tunnel syndrome.
- Conditions
- Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS), Cardiac Amyloidosis
- Trial name
- NCT06907849
- Testing
- 124I-evuzamitide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Carpal Tunnel Syndrome (CTS)
Compare the Effect of Radiofrequency (TECAR) and Ultrasound on Sensation, Hand Dexterity, and Quality of Life in Patients With Carpal Tunnel Syndrome.
The purpose of the current study is to: Compare the effect of radiofrequency (TECAR) therapy and ultrasound on sensation, manual dexterity, and quality of life in individuals diagnosed with carpal tunnel syndrome (CTS).
- Trial name
- TECAR (NCT07700316)
- Testing
- Radiofrequency, Therapeutic Ultrasound
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Delta University for Science and Technology
Phantom Limb Pain
Study of Phantom Limb Pain Suppression Using Neuromodulation Methods
This study assesses the effectiveness of neuromodulation in alleviating pain through the stimulation of peripheral nerves. The research involves implanting electrodes for test stimulation of peripheral nerves (PNS - Peripheral…
- Trial name
- NCT06644807
- Testing
- Motor Cortex Stimulation, Spinal cord stimulation, Peripheral Nerve Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Musculoskeletal Diseases, Median Nerve Disease
Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe…
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided Injection
- Trial name
- NCT06243848
- Testing
- Minimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University