Clinical trials: Peripheral Nerve Injury
Carpal Tunnel Syndrome
Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel Syndrome
The study was conducted to compare the effectiveness of Whole Wrist Mobilization versus Specific Carpal Bone Mobilization in reducing symptoms and improving function in patients with Carpal Tunnel Syndrome (CTS).
- Trial name
- NCT07724717
- Testing
- Specific Bone Mobilization, Whole Wrist Mobilization, Standardized Physiotherapy Treatment
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Carpal Tunnel Syndrome
Efficacy of Pulsed Radiofrequency of the Median Nerve Under Ultrasound Guidance in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy. Although many conservative forms of management including the use of wrist splint, steroid injections and therapeutic ultrasound are applicable…
- Trial name
- NCT02217293
- Testing
- Pulsed Radiofrequency
- Where
- Taiwan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Neuropathic Pain
Topical Lidocaine: Predictors of Response in Peripheral Nerve Injury
The primary purpose is to study the predictive value of preserved nociceptors and large afferent fibers and dynamic mechanical allodynia on the effect of lidocaine patch.
- Trial name
- NCT01112748
- Testing
- Topical lidocaine patch
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Danish Pain Research Center
Peripheral Nerve Injury
Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)
The primary purpose of this research study is to evaluate the safety and possible harms of injecting one's own Schwann cells along with nerve auto-graft after a severe injury to a major nerve has occurred.
- Trial name
- NCT05541250
- Testing
- Autologous Human Schwann Cell
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- W. Dalton Dietrich
Peripheral Nerve Injuries
Robot Assisted Radical Prostatecomy and Positional Injury
Although a condition for surgery, robotic interventions applied with steep Trendelenburg-lithotomy (ST-L) position may cause positional injury and peripheral neuropathy if good position is not achieved on the operating table.
- Trial name
- NCT02437695
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Umraniye Education and Research Hospital
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Neuropathy;Peripheral, Limb Ischemia
Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries
The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed…
- Trial name
- LIMB (NCT07387653)
- Testing
- Lower-Extremity Perfusion Monitoring
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Nerve Injury
Autologous Fat in Peripheral Nerve Injury
The aim of this study is to assess the efficacy of autologous fat graft in enhancing peripheral nerve regeneration. The investigators hypothesize that fat grafting will allow for faster and greater recovery of motor and sensory…
- Trial name
- NCT04653129
- Testing
- Autologous Fat Grafting, Primary Nerve Repair
- Volunteers
- 44 people
- Sponsor
- Assiut University
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Peripheral Nerve Injury
Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination
The purpose of this study is to determine which surgical approach is better for clean transection injury in peripheral nerves in outcomes.
- Trial name
- NCT01116362
- Testing
- primary repair, secondary repair
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Carpal Tunnel Syndrome
Gabapentin for Carpal Tunnel Syndrome
The purpose of this study is to determine whether gabapentin is safe and effective in the treatment of carpal tunnel syndrome (CTS).
- Trial name
- NCT00137735
- Testing
- Gabapentin
- Where
- 2 sites in Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Carpal Tunnel Syndrome
The Effect of Different Molecular Weight of HA for Carpal Tunnel Syndrome
Recently, nerve hydrodissection is utilized to assist ultrasound-guided nerve injection and studies recommend its clinical benefit for peripheral entrapment neuropathy.
- Trial name
- NCT04766918
- Testing
- Sono-guided injection with high molecular weight hyaluronic acid, Sono-guided injection with low molecular weight hyaluronic acid
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Carpal Tunnel Syndrome
Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals
Carpal tunnel syndrome is the most expensive upper extremity work-related musculoskeletal disorder, impacting 10 million people annually and costing employers up to $113,695 per incident.
- Trial name
- NCT02587897
- Testing
- Academic Coursework, Work-Related Hand Activities
- Where
- 3 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Distal Radius Fractures, Lidocaine
Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties…
- Conditions
- Distal Radius Fractures, Lidocaine, Ropivacaine, Fracture Dislocation
- Trial name
- NCT06379490
- Testing
- Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Nordsjaellands Hospital
Carpal Tunnel Syndrome
Percutaneous Treatment of Carpal Tunnel Syndrome With Scan
The objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance.
- Trial name
- ECHOCARPE (NCT02514317)
- Testing
- percutaneous treatment, Ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Spinal Cord Injury, Paralysis
A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
The purpose of this study is to improve the performance of neuroprosthesis for standing after SCI by developing and testing new advanced methods that use multiple contact peripheral nerve electrodes to slow the onset of fatigue…
- Conditions
- Spinal Cord Injury, Paralysis, Tetraplegia, Paraplegia
- Trial name
- NCT01923662
- Testing
- IST-16 (16-Channel implanted stimulator-telemeter
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Carpal Tunnel Syndrome
Effect of Night-time and Full-time Splinting for Carpal Tunnel Syndrome
Carpal tunnel syndrome is a common compression neuropathy of upper extremities. Its usual symptoms are pain, numbness and tingling of fingers, which tend to be worse at night.
- Trial name
- FINCROSS (NCT05637294)
- Testing
- splinting
- Where
- 6 sites in Finland
- Volunteers
- 110 people
- Sponsor
- Tampere University Hospital
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Carpal Tunnel Syndrome (CTS)
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression.
- Trial name
- NCT06902831
- Testing
- Endoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
- Where
- Italy
- Volunteers
- 497 people
- Sponsor
- University of Bari