Clinical trials: Peripheral Nerve Injury Upper Limb
Radial Tunnel Syndrome, Lateral Epicondylitis
Radial Tunnel Syndrome in Resistant Lateral Epicondylitis
Lateral elbow pain can be difficult to diagnose because of the different pathologies or combinations of pathologies that can cause this clinic.
- Conditions
- Radial Tunnel Syndrome, Lateral Epicondylitis, Radial Nerve Compression, Epicondylitis of the Elbow
- Trial name
- NCT04856228
- Testing
- diagnostic posterior interosseous nerve lidocaine injection
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Nerve Injury, Pain Management
Study of Nerve Injuries and Physical Exercise
This study will explore if combining exercise with sensory training can help improve sensory function and reduce pain after an injury to the nerves in the arm and hand.
- Conditions
- Nerve Injury, Pain Management, Sensorial Disturbance
- Trial name
- SNIPE (NCT06846788)
- Testing
- Physical exercise
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Karolinska Institutet
Hand Injury, Wrist Injury
Comparing Two Injection Sites of Local Anesthetic for Hand Surgery
The purpose of this study is to compare two different injection sites for local anesthesia in patients having hand surgery. The hypothesis is that subjects receiving injections around the three nerves of the forearm will provide…
- Conditions
- Hand Injury, Wrist Injury, Finger Injury
- Trial name
- NCT02112006
- Testing
- 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Hand Transplantation, Peripheral Nerve Injuries
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries…
- Conditions
- Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
- Trial name
- NCT03610763
- Testing
- Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Missouri-Columbia
Nerve Injury
Autologous Fat in Peripheral Nerve Injury
The aim of this study is to assess the efficacy of autologous fat graft in enhancing peripheral nerve regeneration. The investigators hypothesize that fat grafting will allow for faster and greater recovery of motor and sensory…
- Trial name
- NCT04653129
- Testing
- Autologous Fat Grafting, Primary Nerve Repair
- Volunteers
- 44 people
- Sponsor
- Assiut University
Stroke, Paralysis Arm
PNS Motor Stimulation Study
Paralysis is one of the most disabling features of Spinal cord injury and stroke. In select cases, where the nerve is intact, stimulation can achieve meaningful muscle contraction e.g. to restore grip and release function.
- Conditions
- Stroke, Paralysis Arm, Spinal Cord Injury
- Trial name
- NCT07810712
- Testing
- Stimulation of the motor unit
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Walton Centre NHS Foundation Trust
Soft Tissue Injuries, Distal Radius Fracture
Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
Trauma and soft injuries of the wrist, hand and fingers have a high incidence, and large social and healthcare costs are generated, mainly due to productivity loss.
- Conditions
- Soft Tissue Injuries, Distal Radius Fracture, Metacarpal Fracture, Carpal Fracture
- Trial name
- NCT04669704
- Testing
- Experimental: Tablet application, Comparator: Conventional treatment
- Where
- 2 sites in Spain
- Volunteers
- 663 people
- Sponsor
- University of Seville
Acute Distal Radius Fracture, Displaced Distal Radius Fracture
Nerve and Hematoma Blocks for Pain Relief During Distal Radius Fracture Reduction
Distal radius fractures, commonly known as wrist fractures, are among the most frequent injuries seen in emergency departments. These injuries often require a closed reduction, a procedure in which the broken bone is manipulated…
- Trial name
- BRAVE (NCT07183904)
- Testing
- Hematoma Block, Median Nerve Block
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Universitario 12 de Octubre
Spinal Cord Injury Cervical, Tetraplegia
Epidural Stimulation for Upper Extremity Function
Restoring upper extremity function in patients with cervical spinal cord injury is extremely important for patients' independence and quality of life.
- Trial name
- NCT06437548
- Testing
- Percutaneous spinal cord stimulation
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Carpal Tunnel Syndrome, Trigger Finger
Alternatives to Hand Therapy for Hand Surgery Patients
Patients will be asked to use a mobile phone app to conduct their hand therapy after having hand surgery.
- Conditions
- Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts, Distal Radius Fracture
- Trial name
- NCT03779958
- Testing
- Mobile App
- Where
- United States
- Sponsor
- Stanford University
Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb
Embodied Virtual Reality for Chronic Pain
Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however…
- Conditions
- Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb, Complex Regional Pain Syndrome I (CRPS I), Complex Regional Pain Syndrome I of Upper Limb
- Trial name
- NCT05160038
- Testing
- Embodied virtual reality
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Zurich
Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS)
Median and Ulnar Nerve Function in Tattoo Artists
This case-control study aims to investigate the effects of occupational hand-arm vibration exposure on median and ulnar nerve functions in tattoo artists.
- Conditions
- Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS), Cubital Tunnel Syndrome
- Trial name
- NCT07496398
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gazi University
Distal Radius Fracture
Comparison of Clinical Outcomes of Distal Radius Fractures Treated Surgically With WALANT and Peripheral Nerve Block
WALANT anesthesia technique has been frequently preferred in hand and upper extremity surgery in recent years. WALANT technique; It stands out with its advantages such as lack of pre-operative anesthesia preparation process…
- Trial name
- NCT05832021
- Testing
- Open reduction and internal fixation (under WALANT), Open reduction and internal fixation (under peripheral nerve block)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Humeral Fractures, Ulnar Nerve Compression
Simple Decompression Versus Anterior Transposition of the Ulnar Nerve
Both simple decompression and anterior transposition of the elbow nerve (ulnar nerve) for acute displaced fractures of the elbow (distal humerus) treated with plate fixation are currently used by surgeons.
- Trial name
- NCT01051869
- Testing
- Simple decompression, anterior subcutaneous transposition
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Unity Health Toronto
Carpal Tunnel Syndrome
Mulligan Mobilization With Arm Movement in CTS Patients
The aim of this study was to investigate the effect of the Mulligan Spinal Mobilization with Arm Movement technique on pain, grip strength and functionality in individuals with carpal tunnel syndrome and to compare it with the…
- Trial name
- NCT07042542
- Testing
- Mulligan Spinal Mobilization with Arm Movement, Conventional Neurodynamic Mobilization, Tendon Gliding and Hand Strengthening Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Beste Gebologlu
Cumulative Trauma Disorders, Carpal Tunnel Syndrome
Protective Brace to Prevent Hand and Arm Injuries
When people use hand-held power tools, their hands and arms vibrate along with the tool they are holding. People who frequently use hand-held power tools may develop injuries related to this vibration.
- Trial name
- NCT00074893
- Testing
- piezoelectric wrist brace
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Chronic Pain Due to Injury, Neuroma of Lower Limb
Botulinum Toxin Type A Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience persistent neuroma pain that may interfere with rehabilitation, prosthesis use, sleep, mobility, and quality of life.
- Conditions
- Chronic Pain Due to Injury, Neuroma of Lower Limb, Neural Injury, Neuroma of Upper Limb
- Trial name
- NEUROQUIET (NCT07626983)
- Testing
- Botulinum Toxin Type A (BoNT-A), Local Anesthetic Solution
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Lymphedema
Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema
this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.
- Trial name
- CDT (NCT05932381)
- Testing
- Complete decongestive therapy, Medical treatment
- Volunteers
- 60 people
- Sponsor
- Cairo University
Distal Radius Fractures, Fracture Dislocation
Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.
The aim of the project is to evaluate the beneficial and harmful effects of an ultrasound-guided brachial plexus nerve block for patients with a distal radius (wrist) fracture in the need of realignment of fractured bone endings…
- Conditions
- Distal Radius Fractures, Fracture Dislocation, Fracture Dislocation of Upper Limb Joint, Colles' Fracture
- Trial name
- NCT06678438
- Testing
- Ultrasound-guided brachial plexus block, Haematoma Block
- Where
- Denmark
- Volunteers
- 1,716 people
- Sponsor
- Nordsjaellands Hospital
Digital Nerve Injury
TISSIUM's Nerve Coaptation Device First-in-Human Clinical Trial
The purpose of this study is to collect initial safety and device performance data of the TISSIUM's nerve coaptation device for the sutureless repair of digital nerve injuries of the hand in which there has been no substantial…
- Trial name
- NCT04327154
- Testing
- TISSIUM™ Nerve Coaptation Device
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Tissium