Clinical trials: Peripheral Neuropathic Pain
Diabetic Neuropathies
Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy
The researchers will study the application of a commercial pulsed magnetic stimulating device to the feet of patients with moderate-severe foot pain secondary to diabetic peripheral neuropathy (DPN).
- Trial name
- NCT00123136
- Testing
- foot energizer
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Pain, Neuropathic
Efficacy Study in Lumbosacral Radiculopathy
This study will be a double-blind, placebo-controlled, parallel group study. After enrolment and initial assessments, subjects will receive 35 days of study medication.
- Trial name
- NCT01110057
- Testing
- GS856553
- Where
- 17 sites in Denmark, France and 3 more
- Volunteers
- 142 people
- Sponsor
- GlaxoSmithKline
Neuropathic Pain, Chronic Pain
Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation
Spinal cord stimulation (SCS) relies on stimulation of pain-relieving pathways in the spinal cord to treat chronic neuropathic pain.
- Trial name
- MOPPStim (NCT03852381)
- Testing
- Spinal Cord Stimulation
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University Health Network, Toronto
Pain
Post-Marketing Surveillance Study on the Safety and Efficacy of Cymbalta (Duloxetine) on Diabetic Peripheral Neuropathic Pain Among Filipino Patients
Primary objective: To estimate the frequency of adverse events, serious and non-serious in Filipino patients with diabetic peripheral neuropathic pain treated with duloxetine 60mg once daily within the study duration of…
- Trial name
- NCT02215798
- Testing
- Cymbalta
- Volunteers
- 269 people
- Sponsor
- Boehringer Ingelheim
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Frozen Shoulder, Adhesive Capsulitis
Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis
Patients aged 18-75 years who present to a tertiary rehabilitation hospital with shoulder pain and restricted range of motion, and who consent to participate, will be included in the study.
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Shoulder Pain, NSAID (Non-Steroidal Anti-Inflammatory Drug)
- Trial name
- NCT07493226
- Testing
- Propionic acid deriaves, acetic acid derivatives, oxicam derivatives
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Fibromyalgia, Painful Diabetic Peripheral Neuropathy
Examination of Pregabalin Access for Treatment of Indicated Pain Disorders: the ExPAND Study
The investigators hypothesize that fibromyalgia (FM) and painful diabetic peripheral neuropathy (pDPN) patients with access restrictions on pregabalin will lead to higher healthcare resource use and cost compared to patients…
- Trial name
- NCT01280747
- Testing
- prior authorization, no prior authorization
- Where
- 17 sites in United States
- Volunteers
- 42 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cervical Radiculopathy
Spinal Mobilization and PNF Comparison on Pain, Disability in Patients With Cervical Radiculopathy
As in this modern era of digitalization; mobile phones, touch pads and computers devices use is increasing, neck pain that radiates into upper limb is also becoming common due to such devices long term use in bad postures or…
- Trial name
- NCT06866821
- Testing
- SMWAM's and PNF C-R Technique, PNF C-R Technique and PT Protocol
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Healthy
Clinical Trial to Compare The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg and Immediate Release Formulation
The purpose of this study is to compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2) while multiple dosing.
- Trial name
- NCT02103647
- Testing
- Immediate release capsule(lyrica 150mg * 2/day), sustained release tablet
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Nerve Entrapment Syndrome, Radiofrequency Ablation
Radiofrequency Ablation of the Superior Cluneal Nerve
Low back pain is one of the most common musculoskeletal disorders affects individuals at least one during lifetime. Chronic low back pain (CLBP) lasts more than 3 months and decreases quality of life and causes work loss all over…
- Conditions
- Nerve Entrapment Syndrome, Radiofrequency Ablation, Low Back Pain
- Trial name
- NCT06240000
- Testing
- Radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Radiculopathy
Effects of Spinal Mobilization With Leg Movement With and Without Neural Flossing Technique in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal condition caused by compression or irritation of the lumbar nerve roots, leading to radiating leg pain, sensory changes, and functional disability.
- Trial name
- NCT07646379
- Testing
- SMWLM along with Neural flossing technique, SMWLM without Neural flossing technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy
Validation Study of Neuropathic Pain
This study seeks to validate clinically evoked or obtained objective pain signs with the patient's corresponding quantified subjective pain symptoms.
- Conditions
- Neuropathic Pain From Spinal Cord Injury, Diabetic Peripheral Neuropathy, Post Herpetic Pain
- Trial name
- NCT00623961
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Chemotherapy-induced Peripheral Neuropathy, Tibial Neuropathy
Tibial Nerve Elastography in Chemotherapy-Induced Neuropathic Pain
This observational study aims to evaluate the tibial nerve stiffness using Shear Wave Elastography (SWE) in patients with chemotherapy-induced peripheral neuropathy (CIPN) compared to healthy volunteers.
- Trial name
- NCT07048431
- Testing
- Shear Wave Elastography Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Diabetes, Peripheral Neuropathy
Lidocaine for Diabetic Peripheral Neuropathy
Diabetic nerve pain [painful diabetic peripheral neuropathy] is a common medical problem with few reliably effective treatments.
- Conditions
- Diabetes, Peripheral Neuropathy, Pain
- Trial name
- NCT02363803
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Washington University School of Medicine
Neuropathic Pain
A Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Painful Diabetic Neuropathy
This is a randomized, double-blind, placebo-controlled, 2-period crossover, 12-week trial to be conducted in 50 subjects with painful diabetic neuropathy.
- Trial name
- NCT01633086
- Testing
- nitric oxide gel
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- China Medical University Hospital
Diabetes Mellitus, Diabetic Neuropathies
Use of taVNS for Painful Diabetic Neuropathy: 12-Week Randomized, Sham-Controlled Trial
This 12-week, randomized, double-blind, sham-controlled, parallel-group trial will evaluate the analgesic and mechanistic effects of home-based transcutaneous auricular vagus nerve stimulation (taVNS) in adults with painful…
- Conditions
- Diabetes Mellitus, Diabetic Neuropathies, Type2diabetes, Neuropathic Pain
- Trial name
- PAK-VAGUS (NCT06292962)
- Testing
- non-invasive transcutaneous vagal nerve stimulation (tVNS)
- Where
- Pakistan
- Volunteers
- 185 people
- Sponsor
- Saima Abass Tahammal
Diabetic Neuropathies
TCMS for the Treatment of Foot Pain Caused By Diabetic Neuropathy
The study will evaluate whether an experimental medical device that emits a series of brief, intense magnetic pulse will relieve foot pain from Diabetic Neuropathy (DN).
- Trial name
- NCT03596203
- Testing
- TransCutaneous Magnetic Stimulator (TCMS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Maryland, Baltimore
Cervical Disc Herniation, Intervertebral Disc Displacement
Gelified Radiopaque Ethanol (Absolute Gel) in Cervical Disc Herniation: an Observational Study in Routine Clinical Practice (GENESIS)
GENESIS is a single-centre, observational, non-interventional, no-profit, investigator-initiated study conducted at Ospedale di Vimercate, ASST Brianza (Italy).
- Conditions
- Cervical Disc Herniation, Intervertebral Disc Displacement, Neck Pain, Chronic Pain
- Trial name
- GENESIS (NCT07832929)
- Testing
- Absolute Gel (radiopaque gelified ethanol)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aurel Mengri
Neuropathy, Neuropathy;Peripheral
Clinical Efficacy of the Erchonia EVRL for Providing Temporary Relief of Idiopathic Peripheral Neuropathy Foot Pain
The purpose of this clinical study is to determine the effectiveness of the Erchonia® EVRL™, manufactured by Erchonia Corporation (the Company), in providing prescription home use application for temporary relief of idiopathic…
- Trial name
- NCT06912646
- Testing
- Erchonia® EVRL™
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Erchonia Corporation