Clinical trials: Peripheral Neuropathy
Danon Disease, Fabry Disease
Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques
What is this study about? This research is focused on improving the care for people with rare heart muscle diseases, known as rare cardiomyopathies.
- Conditions
- Danon Disease, Fabry Disease, Cardiac Amyloidosis, Noonan Syndrome
- Trial name
- NCT07336394
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Diabetic Peripheral Neuropathy
Effect of Circulating lncRNAs on Type 2 Diabetic Peripheral Neuropathy
This project intends to use high-throughput sequencing, molecular biology and bioinformatics technology to clarify the role of target lncrnas in the inflammatory response of DPN, to explore the correlation between target lncrnas…
- Trial name
- NCT04638556
- Testing
- lncRNA detection
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jinshan Hospital Fudan University
CRPS (Complex Regional Pain Syndromes)
Evaluation of Autonomic Cardiac Function in Patients With CRPS
To evaluate the autonomic cardiac function in patients with complex regional pain syndrome
- Trial name
- NCT00560131
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Median Nerve Disease
Effects of Neuromobilization on Median Nerve Elasticity
Purpose: The aim of this study was to investigate the effect of median nerve neuromobilization on median nerve elasticity using shear wave elastography.
- Trial name
- NCT04218175
- Testing
- neuromobilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Istinye University
Diabetes Mellitus, Polyneuropathies
Neurogenic Inflammation in Diabetes
Polyneuropathy is a complication of diabetes mellitus which leads to decreased sensation in arms and legs. This in turn can lead to the development of (infected) foot ulcers.
- Conditions
- Diabetes Mellitus, Polyneuropathies, Arthropathy, Neurogenic
- Trial name
- NCT01370837
- Testing
- Intracutaneous injection of Candida albicans antigen., Temperature measurement.
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cervicobrachial Neuralgia
Longitudinal Experimental Study on ULNTT and Cervico-Thoracic Spine Motion Patterns Relationship
Study Design: Longitudinal Experimental Study Objective: Analyze the relationship between Upper Limb Neural Tension Test (ULNTT1) and cervico-thoracic spine biomechanics using a new motion-capture spine movement data analyzing…
- Trial name
- NCT02632357
- Testing
- Spinal Manipulation
- Where
- Italy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Alzheimer Disease, Neurodegenerative Diseases
Yogic Breathing Changes Salivary Components
Our aim is to analyze two ancient Tamil practices (chanting and breathing exercise) if they are capable of stimulating saliva containing agents that can be beneficial to the nervous system.
- Conditions
- Alzheimer Disease, Neurodegenerative Diseases, Cancer
- Trial name
- NCT02108769
- Testing
- Yogic Breathing, Attention Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Motor Neuropathy
Stroke Recovery Research Based on EEG-fMRI
This study is aimed to investigate the post-stroke motor recovery of patients with ischemic stroke based on their neural features extracted from EEG-fMRI data.
- Trial name
- EEG-fMRI (NCT05427422)
- Testing
- MRI recording, EEG recording
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Carpal Tunnel Syndrome
Gabapentin and Neural Mobilization Pain Reduction Effect Compared to Only Gabapentine
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical gabapentin treatment will be compared to those produced by gabapentin (only) treatment, in subjects who suffer the…
- Trial name
- NCT06778798
- Testing
- Median nerve neural mobilization and oral gabapentin, Gabapentin 300mg
- Where
- Venezuela
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
Chronic Inflammatory Demyelinating Polyneuropathy
A Registered Cohort Study of Immune-Mediated Neuropathies
This study will provide further insights into the natural course of the disease about Immune-Mediated Neuropathies including clinical features，progression, related antibody spectrum and drug treatment effect.
- Trial name
- NCT04292834
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Diabete Type 2
The Effect of Peripheral Neuropathy Symptoms on Temporomandibular Joint Functionality
The aim of this observational case-control study was to investigate the effect of diabetic peripheral neuropathy symptoms on temporomandibular joint functionality in patients with type 2 diabetes.
- Trial name
- NCT06188572
- Testing
- Michigan Neuropathy Screening Instrument, Numeric Pain Scale, Mandibular Function Disorder Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Inguinal Hernias
Ilioinguinal Nerve Block With Local Anesthetic vs. Placebo in Inguinal Hernia Repair Under Spinal Anesthesia
Postoperative pain management remains a critical area of concern in surgical practices, especially in procedures involving the lower abdomen and pelvis.
- Trial name
- NCT07049835
- Testing
- Ilioinguinal/iliohypogastric Nerve Block
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Motor Neuropathy, Sensory Neuropathy
Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients
SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.
- Trial name
- NCT05721040
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Study of CIDP Patients During IVIG Treatment
The aim of this study is to quantify the effect of IVIG treatment in a group of patients with chronic inflammatory demyelinating polyradiculoneuropathy(CIDP), who requires continues treatment of IVIG at regular intervals of 3-10…
- Trial name
- NCT00305266
- Testing
- intravenous gammaglobulin
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lower Limb Amputees, Diabetes
PNS to Improve Vascular Function and Limb Health in Veterans
Establishing a sensitive, scalable physiological test for neurovascular reflex integrity and investigating whether targeted peripheral neural stimulation can enhance perfusion and vasodilatory responsiveness.
- Trial name
- NCT07696988
- Testing
- Chronically Implanted Neural and Muscular Interface, Peripheral Nerve Stimulation (PNS)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Carpal Tunnel Syndrome
Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals
Carpal tunnel syndrome is the most expensive upper extremity work-related musculoskeletal disorder, impacting 10 million people annually and costing employers up to $113,695 per incident.
- Trial name
- NCT02587897
- Testing
- Academic Coursework, Work-Related Hand Activities
- Where
- 3 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
MRI in Diagnosing and Monitoring CIDP
We want to study whether MRI can be useful in diagnosing and monitoring patients with CIDP in maintenance treatment with immunoglobulin
- Trial name
- NCT02017769
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neurofibromatosis Type 1
A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1
The specific aim of this study is to determine whether Lovastatin ™ significantly improves visual spatial learning and/or sustained attention in children with NF1.
- Trial name
- STARS (NCT00853580)
- Testing
- Lovastatin ™
- Where
- 12 sites in United States, Australia
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Peripheral Neuropathy
Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain
The purpose of this study to evaluated Long term outcome after serial Lidocaine infusion when compared with placebo in peripheral neuropathic pain patients in acute stage (less than 6 months) at 3 months after first time of…
- Trial name
- NCT02217267
- Testing
- Lidocaine
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mahidol University