Clinical trials: Peripheral Neuropathy
Carpal Tunnel Syndrome
Role of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome
This prospective study aims to evaluate the median nerve in Carpal Tunnel Syndrome by high-frequency ultrasound and color Doppler in comparison with clinical and Nerve conduction studies.
- Trial name
- NCT04976998
- Testing
- imaging
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Amputation, Diabetes Mellitus
Motor Learning in Individuals With Lower Limb Loss and Chronic Diabetes
Inadequate rehabilitation training after amputation can result in poor patient outcomes, injuries, and wasted healthcare resources.
- Conditions
- Amputation, Diabetes Mellitus, Neuropathy, Diabetic
- Trial name
- NCT03989063
- Testing
- Instructions to perform a motor task (external vs. internal focus instructions)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Neuropathic Pain
The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture
This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who…
- Trial name
- AFNP (NCT06420141)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Indiana University
Piriformis Syndrome
Soft Tissue Techniques in Piriformis Syndrome
The purpose of the study is to compare the effects of active release technique and post isometric relaxation in patients with piriformis syndrome on pain, hip internal rotation range of motion and functional disability.
- Trial name
- NCT04842656
- Testing
- Post isometric relaxation, Active release technique alongwith conventional treatment
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Piriformis Syndrome
Effects of Soft Tissue Mobilization Technique and Piriformis Muscle Stretching Among Patients Having Piriformis Syndrome
It is a randomized control trail in which soft tissue mobilization and piriformis stretching will be compared and study duration will be of five months
- Trial name
- NCT05680402
- Testing
- Soft Tissue mobilization, Piriformis Syndrome (Piriformis muscle stretching)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Autoimmune Disease
Sudoscan in Patients With Autoimmune Disorders
The purpose of this study is to assess the diagnostic utility of Sudoscan in assessing small fiber nerve function, specifically those of the sudomotor, in patients with autoimmune disorders (i.e fibromyalgia and rheumatoid…
- Trial name
- NCT02434458
- Where
- 2 sites in South Korea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Pain, Nociceptive Pain
Radicle Relief 1: A Study of Health and Wellness Products on Pain and Other Health Outcomes
A randomized, blinded, placebo-controlled study assessing the impact of health and wellness products on pain and other health outcomes
- Conditions
- Pain, Nociceptive Pain, Neuropathic Pain
- Trial name
- NCT05589935
- Testing
- Relief Study Product Usage
- Where
- United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Carpal Tunnel Syndrome
Effect of Acupressure on Carpal Tunnel Syndrome in Pregnant Women
This study will be conducted to investigate the effect of acupressure on carpal tunnel syndrome in pregnant women.
- Trial name
- NCT06555926
- Testing
- Acupressure, advices for relieving carpal tunnel syndrome
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiac Amyloidosis
PET/MR Imaging In Patients With Cardiac Amyloidosis
PET scanning (positron emission tomography) is a well-established technique used to identify areas of interest within the body. It involves injecting a radioactive tracer which highlights abnormal areas.
- Trial name
- NCT03626584
- Testing
- 18F-NaF PET
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
CMT1A, CMT (Charcot Marie Tooth Disease)
Longitudinal Biomarkers With Selected Outcome Measures In CMT
The goal of this study is to better understand the progression of CMT1A and identify risk factors influencing disease course. CMT1A, the most common hereditary peripheral neuropathy, shows high variability in individual…
- Conditions
- CMT1A, CMT (Charcot Marie Tooth Disease), CMT 1A, CMT - Charcot-Marie-Tooth Disease
- Trial name
- CMT-BIO-Extend (NCT06794489)
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Carpal Tunnel Syndrome, Trigger Finger
Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery
Does a difference in patient satisfaction and cosmetic outcome exist between wound closure with absorbable or non-absorbable sutures.
- Trial name
- NCT03781141
- Testing
- Wound closure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present there is no specific treatment for this NF1 complication.
- Trial name
- NF1NAC (NCT04481035)
- Testing
- N-acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Rehabilitation, Balance
Peripheral Neuropathy Rehabilitation With Stabilometric Platforms (NEUROSTAB)
The goal of this clinical trial is to learn if the GeaMaster stabilometric platform can support rehabilitation and improve balance and walking ability in adults diagnosed with peripheral neuropathy.
- Trial name
- NEUROSTAB (NCT07029620)
- Testing
- Balance and postural rehabilitation using sensor-based stabilometric platform (GEAMASTER) under static and dynamic conditions, Conventional balance and gait rehabilitation program, Stabilometric assessment in healthy volunteers
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Herpes Zoster, Shingles
ZOSTAVAX™ (Zoster Vaccine Live) Long-term Effectiveness Study (V211-024)
This study will describe the impact of vaccination with ZOSTAVAX™ on the epidemiology of herpes zoster (HZ) in a cohort of vaccinated participants 50 years or age or older, compared to a cohort of unvaccinated participants.
- Trial name
- NCT01600079
- Testing
- ZOSTAVAX™
- Volunteers
- 1,505,647 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Chemotherapy-induced Peripheral Neuropathy
Efficacy of NAC for the Prevention and Relief of PIPN in Women With Ovarian, Tubal, and Peritoneal Cancer
Ovarian cancer is third most common gynecologic cancer in Thai woman, treatment including surgery followed by chemotherapy. Patient usually received paclitaxel every 3 week for 6 cycles, paclitaxel induce peripheral neuropathy is…
- Trial name
- NCT05539053
- Testing
- N Acetylcysteine A, N Acetylcysteine B
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
The goals of this study are: (1) to better understand the relationship between the phenotype and genotype of amyotrophic lateral sclerosis (ALS) and related diseases, including primary lateral sclerosis (PLS), hereditary spastic…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02327845
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
24-hour Blood Pressure Dynamics and Autonomic Adrenergic Regulation in Type 2 Diabetics
Autonomic neuropathy is a common complication of type 2 diabetes mellitus. Symptoms from cardiovascular autonomic neuropathy include, dizziness, orthostatic hypotension and insufficient heart rate and blood pressure (BP)…
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Autonomic Neuropathy, Diabetic Neuropathies
- Trial name
- NCT04208295
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aarhus