Clinical trials: Peripheral Neuropathy Pain
Diabetic Neuropathies
Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Diabetic Peripheral Neuropathy
This study was designed to evaluate the safety and efficacy of Cesamet™ in controlling pain in subjects experiencing pain due to diabetic peripheral neuropathy.
- Trial name
- NCT00380913
- Testing
- Cesamet™ (nabilone)
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- NEMA Research, Inc.
Herpes Zoster
A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster
To evaluate the efficacy, optimal dose and efficacy trend of multiple subcutaneous injections of peginterferon α1b in patients with herpes zoster, and provide support for phase III clinical trials.
- Trial name
- NCT05492591
- Testing
- Peginterferon α1b, Peginterferon α1b with valacyclovir, Valacyclovir
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Institute Of Biological Products
Neuropathic Pain, Sciatic Pain
Ginger Root Extract for Sciatic Pain Individuals
Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain…
- Trial name
- Ginger-NP (NCT06817018)
- Testing
- Ginger
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Leslie Shen
Neuropathic Pain
Brain Activation During Thermal Stimulation in Neuropathic Pain
Patients with peripheral neuropathy frequently exhibit treatment-refractory neuropathic pain. Although both peripheral and central determinants are recognized for the pathophysiological basis of neuropathic pain following…
- Trial name
- NCT00525018
- Testing
- contact heat evoked potential stimulator
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Neuropathic Pain, Complex Regional Pain Syndrome
IV Lidocaine Infusion for Neuropathic Pain
The investigators will conduct a retrospective cohort study of patients who have undergone i.v. lidocaine infusions in the previous 2 years for suspected neuropathic pain of heterogeneous origin.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndrome, Chronic Pain
- Trial name
- NCT05731739
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Neuropathic Pain, Neuroma
Identification of Neuromas by High Resolution Ultrasound in Patients With Peripheral Nerve Injury and Amputations
Neuromas are frequent after trauma and surgery, including amputation and can be identified by high-resolution ultrasound. The role of neuromas as the cause of neuropathic pain is uncertain.
- Trial name
- NCT03051113
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Danish Pain Research Center
Complex Regional Pain Syndrome (CRPS)
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Pain avoidance helps with survival. However, chronic pain patients often avoid valued life activities fearing onset or exacerbation of pain. Hence, pain avoidance no longer protects, but reduces quality of life.
- Trial name
- NCT07791966
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Migraine, Neuropathic Pain
Feasibility and Effectiveness of a Specific App to Delivery Mindfulness Sessions
A standardized behavioural approach based on mindfulness delivered mainly by a specific APP on android will be developed and applied for patients with chronic pain conditions, as migraine and neuropathic pain.
- Trial name
- BE_BI_MIND_APP (NCT05101837)
- Testing
- Home program
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Cancer
A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients
Many types of chemotherapy may cause nerve damage as a side effect. This neurotoxicity can manifest as peripheral sensory neuropathy (characterized by numbness, tingling, or pain).
- Trial name
- NCT00659269
- Testing
- Multivitamin (MV), Multivitamin + Vitamin B12 + Vitamin B6, Chemotherapy
- Where
- 5 sites in United States
- Volunteers
- 319 people
- Sponsor
- New Mexico Cancer Research Alliance
Breast Cancer, Neuropathic Pain
Algology in Oncology Osteopathic Support (ALGOS)
The aim of the study is to evaluate the Impact of add-on osteopathic treatment in the algological course of patients treated for breast cancer : Randomized Controlled Trial.
- Trial name
- ALGOS (NCT05726929)
- Testing
- Osteopathic treatment, Capsaicin QUTENZA Patch (TAU)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Institut Toulousain d'Ostéopathie
CRPS Type II
Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II)
The purpose of this study is to investigated and evaluated the effectiveness of a new surgical technique for the treatment of severe chronic pain stages (Complex Regional Pain Syndrome Type II).
- Trial name
- NCT01392599
- Testing
- SUBCUTANEOUS VENOUS SYMPATHECTOMY (RSVS)
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Sacral Tarlov Cysts, Symptomatic Sacral Cysts
Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study
Brief Summary The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts.
- Conditions
- Sacral Tarlov Cysts, Symptomatic Sacral Cysts, Chronic Pain Related to Sacral Cysts, Neurological Dysfunction Associated With Tarlov Cysts
- Trial name
- NCT06756984
- Testing
- Partial Cyst Wall Resection with Nerve Root Sleeve Plasty, Partial Cyst Wall Resection with Nerve Root Sleeve Reinforcement and Reconstruction:, Autologous Fat/Muscle with Fibrin Glue Microscopic Cyst Filling
- Volunteers
- 150 people
- Sponsor
- Beijing Jishuitan Hospital
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Breast Cancer, Persistent Pain
Persistent Pain After Breast Cancer Treatment (PPBCT) - Risk Factors and Pathophysiological Mechanisms
The study is a prospective cohort study following breast cancer patients from before surgery to one year after. The aims of the study are to determine risk factors that predispose to the development of persistent pain.
- Conditions
- Breast Cancer, Persistent Pain, Lymphedema, Neuropathic Pain
- Trial name
- NCT01523132
- Where
- Denmark
- Volunteers
- 545 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Pain
"MecPain", a New Questionnaire to Assess Chronic Pain Mechanisms.
Validation of a new clinical questionnaire, called 'MecPain', including 12 questions, aimed at better defining the pathophysiological mechanisms of a chronic pain condition.
- Trial name
- MecPain (NCT05713604)
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Grenoble
Postherpetic Neuralgia, Pain
Study of NGX-1998 for the Treatment of Postherpetic Neuralgia
The purpose of this study is to assess the efficacy, safety and tolerability of NGX-1998 applied for 5 minutes for the treatment of postherpetic neuralgia (PHN).
- Trial name
- NCT01228838
- Testing
- NGX-1998
- Where
- 35 sites in United States
- Volunteers
- 183 people
- Sponsor
- NeurogesX
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Spinal Cord Stimulation and Functional MRI
The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate…
- Trial name
- NCT01512121
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vibhor Krishna
Complex Regional Pain Syndrome
Comparative Effects of Mirror Therapy and Standard Physiotherapy in Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by persistent pain, sensory disturbances, motor dysfunction, and functional impairment, often following trauma or surgery.
- Trial name
- (CRPS) (NCT07332884)
- Testing
- Mirror Therapy, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- University of Lahore
Axonal Change, Neuronal, Pain
Effect of the Kv7-channel Opener Flupirtine on the Excitability of Human Peripheral Myelinated Axons in Vivo
Slow axonal Kv7 potassium channels are found along unmyelinated axons and at the nodes of Ranvier of myelinated axons in peripheral nerve.
- Trial name
- NCT01450865
- Testing
- flupirtine
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich