Clinical trials: Peripheral Neuropathy Pain
Complex Regional Pain Syndrome Type I
Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)
Phase 3 Trial of AMBTX-01 (neridronate) for Complex Regional Pain Syndrome Type 1
- Trial name
- CRPS-RISE (NCT07210515)
- Testing
- Neridronate
- Where
- 33 sites in United States
- Volunteers
- 270 people
- Sponsor
- Ambros Therapeutics, Inc.
Neurogenic Thoracic Outlet Syndrome
Free Fat Flap In Recurrent Neurogenic Thoracic Outlet Syndrome Surgical Treatment
The Thoraco-Brachial Outlet Syndrome (T-BOS) corresponds to the entirety of clinical manifestations related to the compression of the branches of the brachial plexus and/or the subclavian vessels during their passage through the…
- Trial name
- FIRST (NCT06172101)
- Testing
- Free fat flap
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Nantes University Hospital
Neuralgia
Home-based EEG Neurofeedback for Chronic Neuropathic Pain
In order to address the growing problem of chronic pain management in the UK, a proof of concept/feasibility open label cohort study has been devised to explore the effectiveness of a home-based self-administered…
- Trial name
- NCT05464199
- Testing
- Neurofeedback training
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Plantar Fasciitis, Heel Pain
Baxter's Nerve Pulsed Radiofrequency Versus Platelet-Rich Plasma Injection or Both Together as a Treatment Modality of Recalcitrant Plantar Fasciitis
Plantar fasciitis is a common condition causing chronic heel pain due to degenerative changes in the tissue supporting the arch of the foot.
- Conditions
- Plantar Fasciitis, Heel Pain, Nerve Compression Syndromes
- Trial name
- NCT07826234
- Testing
- Baxter's Nerve Pulsed Radiofrequency, Autologous Platelet-Rich Plasma Injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Breast Cancer, Persistent Pain
Persistent Pain After Breast Cancer Treatment (PPBCT) - Risk Factors and Pathophysiological Mechanisms
The study is a prospective cohort study following breast cancer patients from before surgery to one year after. The aims of the study are to determine risk factors that predispose to the development of persistent pain.
- Conditions
- Breast Cancer, Persistent Pain, Lymphedema, Neuropathic Pain
- Trial name
- NCT01523132
- Where
- Denmark
- Volunteers
- 545 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuralgia,Postherpetic
The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.
The efficiency of epidural steroid injection in patients who has postherpetic neuralgia is well known. In this study, the purpose is whether the continous epidural steroid injection is effective or not.
- Trial name
- NCT03995563
- Testing
- Dexamethasone, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Chemotherapy-Induced Peripheral Neuropathy, Numbness
Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy
This early phase I trial studies how well fingolimod works in treating patients with chemotherapy-induced nerve pain (neuropathy). Fingolimod acts by suppressing immune reactions in the brain.
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Numbness, Pain, Tingling
- Trial name
- NCT03943498
- Testing
- Fingolimod, Fingolimod Hydrochloride, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Peripheral Neuropathy, Neuropathic Pain
Study of Exablate Model 4000 Type 1.0/1.1 Following the Treatment of Neuropathic Pain
The Exablate 4000 obtained CE Mark for the treatment of Neuropathic Pain in December 2012. The purpose of this post market study is to obtain real world data on the safety and performance of the Exablate treatment for neuropathic…
- Trial name
- NCT05802511
- Testing
- Exablate treatment
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Chronic Pain Syndrome, Fibromyalgia
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
This work will answer two critical questions: 1) Does intensive interdisciplinary pain treatment (IIPT) involving aerobic exercise help normalize pain processing in youth with chronic pain syndromes and 2) Are aerobic fitness…
- Conditions
- Chronic Pain Syndrome, Fibromyalgia, Chronic Headache Disorder, Functional Abdominal Pain Syndrome
- Trial name
- NCT05491499
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Boston Children's Hospital
Sciatica
Adalimumab in Severe and Acute Sciatica
The purpose of this study is to determine whether adalimumab (a TNF-alpha inhibitor) is effective in the treatment of severe and acute sciatica.
- Trial name
- ASAS (NCT00470509)
- Testing
- Adalimumab
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Hospital, Geneva
Complex Regional Pain Syndrome Type I
Transcutaneous Auricular Vagus Nerve Stimulation Added to Rehabilitation for Complex Regional Pain Syndrome Type I
This randomized, participant- and assessor-blinded, sham-controlled study will evaluate the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) added to standard rehabilitation in adults with complex…
- Trial name
- taVNS-CRPS-I (NCT07711392)
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation, Standard Rehabilitation Program
- Volunteers
- 20 people
- Sponsor
- Liv Hospital Vadistanbul
Neuropathic Pain
Paracetamol and Neuropathic Pain
The aim of this study is to evaluate the analgesic effect of paracetamol in patients suffering from pain with a peripheral neuropathic component in the presence of their usual treatment.
- Trial name
- PAeoNy (NCT03559985)
- Testing
- paracetamol
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Phantom, Pain, Neuropathic
Valproic Acid for the Prevention of Post-Amputation Pain
The objectives of this study are, to test the effectiveness of Valproic Acid (VPA) in the prevention of chronic neuropathic and post-amputation pain, as well as to further define the underlying inflammatory and epigenetic…
- Trial name
- NCT01928849
- Testing
- Valproic Acid, Cherry Syrup
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Diabetic Neuropathies, Herpes Zoster
Dextromethorphan Versus Placebo for Neuropathic Pain
In our current clinical trial, we are comparing the effects of two NMDA receptor antagonists to placebo in patients with painful distal symmetrical diabetic neuropathy or post-herpetic neuralgia.
- Conditions
- Diabetic Neuropathies, Herpes Zoster, Neuralgia
- Trial name
- NCT00001344
- Testing
- dextromethorphan
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Lumbar Radiculopathy
Effect of Sciatic Nerve Neurodynamic Sliding on Pain, Disability, and Balance in Patients With Lumbar Radiculopathy
This study will be conducted to evaluate the effect of sciatic nerve slider mobilization on pain intensity. Also, to evaluate the impact of sciatic nerve mobilization on functional disability, and to determine the influence of…
- Trial name
- NCT07458399
- Testing
- Selected conventional physical therapy program, Sciatic nerve slider mobilization
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Neuropathic Pain
Lidocaine and Neuroma Pain Related Modalities
Background Subanesthetics concentrations of lidocaine are able to produce a differential block of the ectopic discharges, but not propagation of impulses, suppressing differentially the associated neuropathic pain symptoms.
- Trial name
- NCT02300038
- Testing
- Lidocaine (Xylocaine), NaCl
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Distal Radius Fracture, Chronic Regional Pain Syndrome
Effectiveness of Virtual Reality in Hand Therapy
The purpose of this study is to determine if the use of Virtual Reality as an intervention for patients following specific hand injuries will positively affect patients with decreased hand function and reduce pain and improve…
- Conditions
- Distal Radius Fracture, Chronic Regional Pain Syndrome, Flexor Tendon Rupture
- Trial name
- NCT05188040
- Testing
- Virtual Reality Exercises
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Timothy Uhl
Breast Neoplasms
Effect of Kinesiotaping for the Treatment of Hormone-induced Myalgia in Women Given Breast Cancer Survivors
Background: It has been demonstrated that aromatase inhibitors (AIs) are more effective than tamoxifen in reducing breast cancer recurrence.
- Trial name
- KITMYCAN (NCT02406794)
- Testing
- Neuromuscular taping
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- University of Malaga
Residual Limb Pain, Amputation Neuroma
Surgical Treatments for Postamputation Pain
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP).
- Conditions
- Residual Limb Pain, Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic
- Trial name
- NCT05009394
- Testing
- Targeted Muscle Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), Standard neuroma treatment, neuroma excision, and muscle burying
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 110 people
- Sponsor
- Prometei Pain Rehabilitation Center
Pain
[S,S]-Reboxetine Long Term Safety Study In Chronic Painful Diabetic Peripheral Neuropathy.
The purpose of this study is to assess the long-term safety and tolerability of [S,S]-Reboxetine in patients with chronic painful diabetic peripheral neuropathy
- Trial name
- NCT00348894
- Testing
- [S,S]-Reboxetine, Any
- Where
- 93 sites in United States, Argentina and 12 more
- Volunteers
- 136 people
- Sponsor
- Pfizer
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