Clinical trials: Peripheral Neuropathy Pain
Chemotherapy Induced Peripheral Neuropathy (CIPN), Cancer
Effect of GMI With and Without NM on LE in Cancer Patients With CIPN
The goal of this interventional study is to learn if graded motor imagery with or without added neural mobilization can treat chemotherapy induced nerve related symptoms in lower limbs of cancer patients.
- Trial name
- CIPN (NCT07712302)
- Testing
- Graded Motor Imagery, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Back Pain
Spinal Cord Stimulation for Chronic and Intractable Back Pain
The purpose of this study is to evaluate the efficacy of spinal cord stimulation (SCS) using the Precision implantable neurostimulation device for chronic and intractable back pain in subjects who are not candidates for surgery…
- Trial name
- NCT00370695
- Testing
- Precision Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Scientific Corporation
Dry Eye, Neuropathic Pain
Prospective Single-center Long-term Follow-up Study of a Series of Cases Previously Included in the QUALVIDON Study
Dry eye affects millions of people around the world. Some dry eye patients complain of neuropathic eye pain that can affect their quality of life.
- Trial name
- QUALVIDON2 (NCT05523531)
- Testing
- Self-administered questionnaires, Bilateral ophthalmologic examination
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Electroacupuncture, Acupuncture
Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy
This is a controlled clinical trial with the aim to study the effects of electroacupuncture on neuropathic pain reduction, quality of life and changes in sensory and motor nerve conduction velocity in patients with type 2…
- Conditions
- Electroacupuncture, Acupuncture, Diabetic Polyneuropathy, Diabetic Peripheral Neuropathy
- Trial name
- EA&DPN (NCT05521737)
- Testing
- Electroacupuncture
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Neuropathy, Diabetic
Relaxation and Meditation Techniques on Pain, Fatigue and Quality of Life
Patients with painful diabethic peripheral neuropathy will be entered.. Participants will be randomized to one of three study arms: Arm 1: relaxatio; Arm 2:meditation Arm 3: Attention matched control Hypothesis: Progressive…
- Trial name
- NCT04287439
- Testing
- Progressive muscle relaxation, Mindfulness meditation, Attention matched control
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Hacettepe University
Cardiac Amyloidosis, Chest Pain
CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD).
- Trial name
- CHEST-CA (NCT07435168)
- Testing
- Screening thourgh examinations including bonescintigraphy
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Radiculopathy
Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
The main objective of this study is to determine whether interventional treatment (i.e. epidural steroids), conservative therapy, or the combination, is superior for cervical radiculopathy.
- Trial name
- NCT01144923
- Testing
- Gabapentin and/or Nortriptyline, Physical therapy, Epidural Steroid Injections (ESI), Combination treatment
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Johns Hopkins University
Diabetic Peripheral Neuropathic Pain, Balance Changes
Buerger Exercises With Whole Body Vibration in Diabetic Peripheral Neuropathy
The goal of this clinical trial is to determine if a combined intervention of Buerger exercises and whole-body vibration therapy can improve pain, circulation, and balance in adults with diabetic peripheral neuropathy.
- Conditions
- Diabetic Peripheral Neuropathic Pain, Balance Changes, Ankle Brachial Index
- Trial name
- NCT06737861
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Neuropathic Pain
Memantine and Post-mastectomy Neuropathic Pain
The aim of this study is to evaluate if memantine administered for four weeks starting two weeks before surgery induces a decrease in pain intensity at 3 months post-mastectomy.
- Trial name
- CLEMANTINE (NCT03686774)
- Testing
- Memantine, no memantine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cervical Radiculopathy
Effects of Thoracic Mobility Versus Stretching Exercise Program in Patients of Cervical Radiculopathy
The study will be a randomized clinical trial with a sample size of 44 to determine the effects of thoracic mobility versus thoracic stretching exercises on pain, range of motion, and function in patients with cervical…
- Trial name
- NCT05404646
- Testing
- Thoracic mobility exercises with conventional physical therapy for cervical radiculopathy, Thoracic stretching exercises with conventional physical therapy for cervical radiculopathy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Inguinal Hernia
Electrocoagulation Employment During TAPP Inguinal Hernia Repair
Laparoscopic TAPP (transabdominal preperitoneal) hernia repair presents a minimally invasive surgical procedure, which tends to be a gold standard in a wide range of inguinal hernia operations.
- Trial name
- NCT03566784
- Testing
- Inguinal hernia repair
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Piriformis Syndrome
Effects of Hold Relax With Agonist Contraction and Active Release Therapy on Clinical Outcomes in Piriformis Syndrome
The aim of this study is to compare the effects of hold relax agonist contraction and active release therapy on reducing pain intensity, improving functioning and sleep quality in patient with piriformis syndrome.
- Trial name
- NCT05370378
- Testing
- Hold Relax with Agonist Contraction, Active Release Therapy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Postherpetic Neuralgia, Electroacupuncture
The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture
Based on the inclusion and exclusion criteria, patients with head and face PHN who met the requirements were selected as trial subjects, and the efficacy was clarified in a randomized controlled design trial.
- Conditions
- Postherpetic Neuralgia, Electroacupuncture, Infrared Thermography
- Trial name
- NCT06420778
- Testing
- electroacupuncture, Pregabalin
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Zhejiang Chinese Medical University
Neuropathic Pain
Lidocaine and Neuroma Pain Related Modalities
Background Subanesthetics concentrations of lidocaine are able to produce a differential block of the ectopic discharges, but not propagation of impulses, suppressing differentially the associated neuropathic pain symptoms.
- Trial name
- NCT02300038
- Testing
- Lidocaine (Xylocaine), NaCl
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sciatica Acute, Sciatica Pain
Ultrasound-guided Transgluteal Sciatic Nerve Hydrodissection for the Treatment of Sciatica in the Emergency Department
The goal of this observational study is to see whether it would be feasible to treat patients who come to the emergency department with pain related to sciatica using an ultrasound guided injection of dextrose in water solution…
- Trial name
- NCT07588126
- Testing
- Ultrasound guided transgluteal sciatic nerve hydrodissection
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Kaiser Permanente
Neuropathic Pain
'Fix the Dysfunction' Concept for Mechanism-based Pharmacological Treatment of Neuropathic Pain by Drug
Introduction Treatment of neuropathic pain has been a goal of numerous research projects for the last half century, with overall disappointing results.
- Trial name
- 0381-16 (NCT03276689)
- Testing
- Duloxetine, Pregabaline
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Complex Regional Pain Syndrome
Evaluation of the Physiodoloris Pain Monitor in Patients With Complex Regional Pain Syndrome
A French University team (M. Jeanne, MD, and M. LOGIER, Ph D) have developed a pain assessment tool based on the analysis of the variability heart rate which evaluates the Analgesia Nociception Index (ANI).
- Trial name
- ANI-ALGO (NCT02663284)
- Testing
- Ropivacaine 0.5%
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopital Foch
Chemotherapeutic Agent Toxicity, Neurotoxicity
Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy
RATIONALE: Electronic stimulation using a MC5-A Scrambler may help relieve pain in patients who develop peripheral neuropathy while undergoing chemotherapy treatments for cancer.
- Conditions
- Chemotherapeutic Agent Toxicity, Neurotoxicity, Pain, Peripheral Neuropathy
- Trial name
- NCT00952848
- Testing
- questionnaire administration, Sensory Neuropathy Scale instrument, Quality of Life instrument
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Carpal Tunnel Syndrome
Dual Task During Exercise for Carpal Tunnel Release
The aim of this study will be to evaluate the effect of the dual task on hand motor performance, pain, functionality and psychosocial factors in patients with carpal tunnel syndrome undergoing surgery.
- Trial name
- DTCTR (NCT05593952)
- Testing
- Dual task, Single task
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Valencia
Diabetic Peripheral Neuropathy (DPN), Pain
Study on Serum Transcriptomics and Metabolomics in Patients With Diabetic Peripheral Neuropathy
This part of the study enrolled 30 sex- and age-matched healthy controls, 30 diabetic patients without peripheral neuropathy, and 30 patients with diabetic peripheral neuropathy (DPN).
- Trial name
- NCT07518433
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
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