Clinical trials: Peripheral Neuropathy Pain
Peptic Ulcer
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450658
- Testing
- HZT-501, Ibuprofen
- Volunteers
- 627 people
- Sponsor
- Amgen
Carpal Tunnel Syndrome (CTS), Heel Pain Syndrome
Observational Study - Heel Syndrome and Relationship to Flexor Retinacular Ligament Thickness
Numerous studies have examined the relationship between carpal tunnel syndrome and the thickness of the flexor retinacular ligament.
- Trial name
- ESTEREL (NCT07375134)
- Where
- France
- Volunteers
- 144 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Traumatic Spinal Cord Injury, Neuropathic Pain
Biomarkers for Pain in Spinal Cord Injury Patients
The investigators propose to compare plasma protein profiles for SCI patients with/without chronic neuropathic pain in order identify biomarker(s) that are associated with this medical condition.
- Trial name
- SCI Pain (NCT00913471)
- Testing
- blood samples
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Neuropathic Pain, Chronic Neuropathic Pain
High-Frequency rTMS Over the DLPFC for Chronic Low Back Pain
Neuropathic pain is a chronic condition that significantly affects quality of life and often responds poorly to conventional pharmacological treatments.
- Trial name
- RTMS-CLBP (NCT07468799)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Hasanuddin University
Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS)
Median and Ulnar Nerve Function in Tattoo Artists
This case-control study aims to investigate the effects of occupational hand-arm vibration exposure on median and ulnar nerve functions in tattoo artists.
- Conditions
- Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS), Cubital Tunnel Syndrome
- Trial name
- NCT07496398
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetic Polyneuropathy
Painful Diabetic Polyneuropathy Trial With a New Centrally Acting Analgesic
The purpose of this trial is to determine whether the new centrally active analgesic and MS Continus® are effective in the treatment of painful diabetic polyneuropathy.
- Trial name
- NCT00878293
- Testing
- GRT6005, MS Continus®
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Tris Pharma, Inc.
Cancer, Neuralgia
Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
Rationale: Often, incurable cancer patients suffer from severe symptoms as (neuropathic) pain and fatigue with polypharmaceutic interventions as a consequence.
- Trial name
- Off-label (NCT00740571)
- Testing
- amitriptyline, pregabalin
- Where
- 2 sites in Netherlands
- Volunteers
- 130 people
- Sponsor
- Radboud University Medical Center
Obstructive Sleep Apnea
A Pilot Study of Biomarkers in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and is a risk factor for postoperative complications, including respiratory and cardiac events and delirium.
- Trial name
- Cytokine OSA (NCT02325687)
- Testing
- Lumbar Puncture (Standard-of-Care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Morton's Neuroma, Pain Management
Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma
This is a Proof-of-Concept Trial to define the safety, efficacy and feasibility of a cryoanalgesic device (iovera°®) for the treatment of pain in subjects diagnosed with Morton's Neuroma, who have failed conservative therapies.
- Trial name
- NCT05604144
- Testing
- Cryoanalgesia (iovera°®)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Northern California Research Trials, Inc.
SCI - Spinal Cord Injury
tDCS and VI to Treat Neuropathic Pain and Function in SCI
Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) will be applied for patient who suffer from neuropathic pain following spinal cord injury The tDCS treatment will be coupled with a video of a man…
- Trial name
- NCT03052244
- Testing
- tDCS+VI
- Volunteers
- 100 people
- Sponsor
- Loewenstein Hospital
Pain, Neuropathic Pain
Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain
The primary aim of this study is to investigate if AZD1386 is efficacious as an analgesic in patients with peripheral neuropathic pain.
- Trial name
- AVANT (NCT00976534)
- Testing
- AZD1386
- Where
- 12 sites in Canada, Denmark and 2 more
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Lung Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT02960971
- Testing
- Thoracic surgery for lung cancer
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Danish Pain Research Center
Unilateral Carpal Tunnel Syndrome
Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves
This study is being done to see how well a new investigational medical device, the StimRouter (STR) System, will work to treat the chronic pain in people who have failed previous treatments for Carpal Tunnel Syndrome (CTS) pain…
- Trial name
- StimRouter (NCT00665132)
- Testing
- StimRouter System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Bioness Inc
Musculoskeletal Pain, Neuropathic Pain
Virtual Reality (VR) Self-Hypnosis Software
This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic…
- Conditions
- Musculoskeletal Pain, Neuropathic Pain, Neuralgia
- Trial name
- NCT06398847
- Testing
- Virtual Reality headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
CRPS, Chronic Regional Pain Syndrome
TNF-alpha Inhibition in CRPS: A Randomized Controlled Trial
Studying the effects of Etanercept (an anti-Tumor Necrosis Factor alpha) on early Chronic Regional Pain Syndrome (CRPS). Our hypothesis is that Etanercept will improve patient symptoms if given in early CRPS.
- Trial name
- NCT02031211
- Testing
- Etanercept
- Where
- United States
- Sponsor
- Stanford University
Diabetic Peripheral Neuropathy
Laser Therapy for Diabetic Peripheral Neuropathic Pain
The proposed study is a randomized, double-blinded clinical trial to evaluate the efficacy of a course of laser therapy on peripheral neuropathic pain in persons with diabetes.
- Trial name
- NCT02328911
- Testing
- Laser treatment
- Where
- United States
- Sponsor
- University of Miami
Postherpetic Neuralgia
Erector Spinae Plane Block in Post-herpetic Neuralgia
This randomized clinical study will be carried out on 72 patients admitted to the pain clinic in Tanta University Hospitals with post-herpetic neuralgia.
- Trial name
- NCT04546334
- Testing
- Medical treatment, Real Erector Spinae block, Real Erector Spinae block with magnesium sulphate
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Breast Cancer, Peripheral Neuropathies
The Effect of Walking Exercise Based on TOUS on Peripheral Neuropathy and Arthralgia-Myalgia in Women With Breast Cancer
Peripheral neuropathy from paclitaxel is a cause for concern. This situation also affects the patient, family and healthcare professionals. All health personnel are responsible for its care.
- Conditions
- Breast Cancer, Peripheral Neuropathies, Arthralgia, Myalgia
- Trial name
- NCT05448209
- Testing
- walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Necmettin Erbakan University
Neuralgia, Postherpetic
A Study Assessing Efficacy of Brivaracetam in Subjects With Persistent Pain After Shingles (Post-herpetic Neuralgia)
Study will assess efficacy, safety and tolerability of brivaracetam in post-herpetic neuralgia (PHN). Duration of 7 weeks divided into 3 periods with no up-titration, nor down-titration.
- Trial name
- NCT00160667
- Testing
- Brivaracetam
- Where
- 50 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 152 people
- Sponsor
- UCB Pharma
Contact Allergy, Neuropathic Pain
Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC)
To find out if the use of an intranasal tear neurostimulator (ITN), may be useful in decreasing the pain symptoms felt by patients who experience contact lens discomfort.
- Trial name
- INTAC (NCT04240587)
- Testing
- TrueTear™ intranasal neurostimulator (ITN)
- Where
- United States
- Sponsor
- Tufts Medical Center
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