Clinical trials: Peripheral Neuropathy Pain
Cerebral Palsy, Excessive Crying
Excessive Crying in Children With Cerebral Palsy and Communication Deficits
Management of excessive crying in children with cerebral palsy and communication deficits [ECCCPCD] was guided by the associated clinical findings and investigations.
- Conditions
- Cerebral Palsy, Excessive Crying, Pain
- Trial name
- ECCCPCD (NCT04523935)
- Testing
- Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline.
- Volunteers
- 131 people
- Sponsor
- Sathbhavana Brain Clinic
Reflex Sympathetic Dystrophy, Causalgia
Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror Therapy
AlgoMIR project born thanks to a meeting between pain professionals and re-education staff. The goal of this project is to develop and evaluate a program of learning with exercises by mirror therapy, that could be easily shared…
- Trial name
- AlgoMIR (NCT02667717)
- Testing
- Mirror therapy, Usual care
- Where
- 5 sites in France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sciatica Acute, Sciatica
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
The goal of this clinical trial is to compare different combinations of diclofenac with diclofenac monotherapy in acute sciatica.
- Trial name
- EDCLAS (NCT05626140)
- Testing
- Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Medical Sciences
Lumbar Disc Herniation With Radiculopathy
Comparison of the Effectiveness of Ultrasound-Guided Periradicular Injections in Patients With Lumbar Radicular Pain
This study aims to compare the effects of different ultrasound-guided periradicular injection solutions in patients with chronic unilateral radicular pain caused by a single-level lumbar disc herniation.
- Trial name
- NCT07771374
- Testing
- Lidocaine Hydrochloride 2% Injection Solution, Dexamethasone 4 Mg/mL Injectable Solution, Dextrose 5% Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Diabetic Peripheral Neuropathic Pain
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
- Trial name
- NCT06619860
- Testing
- VX-993, Pregabalin
- Where
- 47 sites in United States, Canada and 4 more
- Volunteers
- 300 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Neuropathic Pain, Neuropathy;Peripheral
Posterior-superior Insula Deep Brain Stimulation in Refractory Peripheral Neuropathic Pain Patients
This study evaluates the long term pain relief after deep brain stimulation on posterior-superior insula (PSI) in patients with refractory peripheral neuropathic pain who responded to real but not to sham non-invasive stimulation…
- Trial name
- PSI-DBS (NCT04279548)
- Testing
- Deep Brain Stimulation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Chronic Pain Syndrome, Fibromyalgia
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
This work will answer two critical questions: 1) Does intensive interdisciplinary pain treatment (IIPT) involving aerobic exercise help normalize pain processing in youth with chronic pain syndromes and 2) Are aerobic fitness…
- Conditions
- Chronic Pain Syndrome, Fibromyalgia, Chronic Headache Disorder, Functional Abdominal Pain Syndrome
- Trial name
- NCT05491499
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Boston Children's Hospital
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Diabetes Mellitus
Effect of Self-Foot Massage on Diabetic Individuals
The aim of this study is to evaluate the effect of self-foot massage on peripheral neuropathic pain, peripheral skin temperature and patient comfort in individuals with diabetes.
- Trial name
- NCT04906226
- Testing
- Self-foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Aksaray University
Peripheral Neuropathy, Painful Diabetic Neuropathy
A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral Neuropathy
This is a randomized outpatient, double-blind, placebo-controlled, multiple-site study of the safety, tolerability, and exploratory efficacy of topically administered WST-057 (4% pirenzepine free base monohydrate) for 24 weeks in…
- Conditions
- Peripheral Neuropathy, Painful Diabetic Neuropathy, Diabetic Neuropathies, Painful
- Trial name
- NCT04005287
- Testing
- WST-057 (4% pirenzepine) Lose Dose 2mL, WST-057 (4% pirenzepine) High Dose 4mL
- Where
- 5 sites in Canada
- Volunteers
- 58 people
- Sponsor
- WinSanTor, Inc
Cervical Radiculopathy, Cervical Root Compression
Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy
This study compares anterior cervical decompression and fusion (ACDF) to posterior foraminotomy (PF) in surgical treatment for cervical radiculopathy (CR) caused by root canal compression, in a multicenter prospective randomized…
- Trial name
- OMSAP (NCT04177849)
- Testing
- ACDF, PF
- Where
- 4 sites in Sweden
- Volunteers
- 110 people
- Sponsor
- Region Örebro County
Neuropathic Pain, Chronic Pain
Analysis of Selected Biochemical Parameters in Cerebrospinal Fluid and Peripheral Blood in the Treatment of Neuropathic Pain Using Spinal Cord Stimulation (SCS)
This project aims to identify key cells and molecules involved in the development and modulation of neuropathic pain treated with spinal cord stimulation (SCS).
- Conditions
- Neuropathic Pain, Chronic Pain, Spinal Cord Stimulation (SCS)
- Trial name
- NCT07153211
- Testing
- Immunological Factors
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Pawel Sokal
Neuropathic Pain
A Study to Assess Safety, Tolerability and Exposure of 4ET1103 in Healthy Human Volunteers
This study will dose healthy human volunteers with either active drug (4ET1103) or placebo. Each study subject will receive a single dose of either active drug or placebo, and will then be monitored for safety, tolerability and…
- Trial name
- NCT07586514
- Testing
- LY4286533
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- 4E Therapeutics
Pain, Postoperative, Pain, Acute
Lidocaine and Magnesium and Ketamine in Gynecological Surgery
The aim of this study will be to investigate the effect of a combination of intravenous infusions of lidocaine and magnesium versus a combination of intravenous infusions of lidocaine and ketamine versus an intravenous infusion…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- annie-sophia (NCT04622904)
- Testing
- lidocaine-magnesium infusion, lidocaine-ketamine infusion, lidocaine infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
HIV, Sensory Neuropathy
Clinical Phenotyping and Genotyping of HIV-Associated Sensory Neuropathy: The HIV-POGO Study
This study aims to recruit a cohort of HIV patients with and without HIV-SN and to identify genetic risk factors for the development of HIV-SN and neuropathic pain.
- Conditions
- HIV, Sensory Neuropathy, Neuropathic Pain
- Trial name
- HIV-POGO (NCT02555930)
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Imperial College London
Small Fiber Neuropathy
Chronic Pain Rehabilitation in Patients With Small Fiber Neuropathy
Small fiber neuropathy (SFN) is a condition that is dominated by invalidating neuropathic pain. Pharmacological neuropathic pain treatment is often disappointing, since pain reduction is mostly slight and side effects can be…
- Trial name
- NCT05798949
- Testing
- Chronic pain rehabilitation: exposure in vivo, Chronic pain rehabilitation: graded activity, Chronic pain rehabilitation: acceptance and commitment therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Cervical Radiculopathy
Simultaneous Traction and Neural Mobilization
Neck pain is a frequently reported complaint of the musculoskeletal system which generally has a huge impact on health care expenditure; ascribed to visits to health care providers, disability, and sick leaves.
- Trial name
- NCT05021510
- Testing
- Simultaneous Cervical Traction & Neural Mobilization, consecutive Cervical Traction & Neural Mobilization
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Neuralgia, Pain
Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia Pain
The purpose of this study is to gain initial information on the tolerability of high-dose capsaicin patches in patients with Painful Postherpetic Neuralgia.
- Conditions
- Neuralgia, Pain, Peripheral Nervous System Diseases, Herpes Zoster
- Trial name
- NCT00034710
- Testing
- Capsaicin Patch
- Where
- 8 sites in United States
- Volunteers
- 42 people
- Sponsor
- NeurogesX
Lumbar Radiculopathy
Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain
The present study aims to compare directly the efficacy of two noninvasive neurostimulation techniques : repetitive transcranial magnetic stimulation and transcranial direct electrical current of the motor cortex in patients with…
- Trial name
- NCT02030626
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Ambroise Paré Paris
Radiculopathy, Low Back Pain, Mechanical
Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back
Chronic low back pain is a common problem which results in reduced functionality, quality of life and general well being. Conservative treatment includes patient education, exercise, maintaining a healthy body mass index and…
- Conditions
- Radiculopathy, Low Back Pain, Mechanical, Herniated Disk Lumbar
- Trial name
- NCT03835182
- Testing
- Ultrasound group, Short wave diathermy group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Baskent University