Clinical trials: Peripheral Neuropathy Pain
Piriformis Syndrome, Gluteal Pain
Diagnostic Accuracy of Clinical Tests and Diagnostic Criteria for Piriformis Syndrome
Piriformis syndrome is a clinical condition characterized by buttock pain and/or sciatic-like symptoms, and its diagnosis remains challenging because there is no universally accepted diagnostic standard.
- Trial name
- NCT07473349
- Testing
- Ultrasound-Guided Piriformis Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Neuropathic
Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study
use of dexmedtemodine to augment analgesia in cases of failed back surgery
- Trial name
- NCT05349448
- Testing
- Hylase plus Triamcinolone plus sterile isotonic saline, Hylase plus Dexmedetomidine plus Triamcinolone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Complex Regional Pain Syndrome (RSD)
A Study of CC-5013 in the Treatment of Complex Regional Pain Syndrome (CRPS)
This is a multicenter, open-label study in adult subjects with Type 1 Complex Regional Pain Syndrome. Subjects diagnosed with unilateral Type 1 CRPS will be enrolled sequentially to receive CC-5013 10 mg/day orally.
- Trial name
- CRPS (NCT00067743)
- Testing
- Lenalidomide
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Celgene Corporation
Cervical Radiculopathy, Degenerative Disc Disease
Restore CLINICAL TRIAL
This is a prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the…
- Trial name
- NCT01609374
- Testing
- M6-C Artificial Cervical Disc, Anterior plate system with corticocancellous allograft bone
- Volunteers
- 258 people
- Sponsor
- Spinal Kinetics
Cervical Radiculopathy
Median Nerve Flossing Technique in Patients With Cervical Radiculopathy
Cervical radiculopathy is a condition of cervical spinal nerve roots which occurs as a result of compression and inflammatory pathology from a space occupying lesion.
- Trial name
- NCT07062718
- Testing
- Median nerve flossing technique and conventional physical therapy, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University
Traumatic Spinal Cord Injury
Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP)
The goal of this feasibility trial is to learn if exoskeleton or robotic walking works to reduce nerve (neuropathic) pain after spinal cord injury.
- Trial name
- ExSCIP (NCT06463418)
- Testing
- Ekoskeleton (Intervention), Relaxation (Comparator)
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Dublin
Neuropathic Pain
Topical Lidocaine: Predictors of Response in Peripheral Nerve Injury
The primary purpose is to study the predictive value of preserved nociceptors and large afferent fibers and dynamic mechanical allodynia on the effect of lidocaine patch.
- Trial name
- NCT01112748
- Testing
- Topical lidocaine patch
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Danish Pain Research Center
Postherpetic Neuralgia, Shingles
A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)
This study will evaluate the safety and efficacy of 2 weeks of topical KD7040 versus placebo in the treatment of postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Shingles, Herpes Zoster, Neuropathic Pain
- Trial name
- NCT00576108
- Testing
- KD7040 Topical Gel
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Kalypsys, Inc.
Nerve Pain, Neuropathic Pain
PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin
The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.
- Conditions
- Nerve Pain, Neuropathic Pain, Nociceptive Pain, MIxed Pain (Nociceptive and Neuropathic)
- Trial name
- NCT06599151
- Testing
- [18F]FTC-146
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stanford University
Extracorporeal Shock Wave, Radial Shock Wave
Radial Shockwave Versus Low Level Laser Therapy in Patients With Chronic Piriformis Muscle Syndrome
The study aims to compare the effects of radiation shockwave and low-level laser therapy on piriformis muscle thickness, lower extremity function, pain intensity, and hip range of motion in patients with piriformis syndrome.
- Conditions
- Extracorporeal Shock Wave, Radial Shock Wave, Low Level Laser, Piriformis Muscle Syndrome
- Trial name
- NCT06762197
- Testing
- Conventional treatment, shockwave therapy, low level laser therapy
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Cairo University
Complex Regional Pain Syndromes
Pregabalin Versus Placebo as an Add on for Complex Regional Pain Syndrome (CPRS) of the Upper Limb Managed by Stellate Ganglion Block (The PREGA Study)
The purpose of this study is to assess the efficacy of pregabalin in patients with complex regional pain syndrome Type I and to determine whether it provides clinically significant pain relief and whether it improves functioning…
- Trial name
- PREGA (NCT00891397)
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- McMaster University
Polyneuropathies
Individual Patient Expanded Access IND to Treat Polyneuropathy
This Individual Patient Expanded Access IND has been created as requested by an 58-year-old man who suffers from Polyneuropathy due to Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, and Skin abnormalities…
- Trial name
- NCT04064983
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Spinal Cord Injuries, Spinal Cord Diseases
Impact of Peripheral Afferent Input on Central Neuropathic Pain
The overarching aim of this study is to investigate the contribution of peripheral afferent input to spontaneous and evoked central neuropathic pain after a spinal cord lesion or disease.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Syringomyelia
- Trial name
- NCT05646810
- Testing
- Lidocaine (10 mg/ml), Isotonic saline
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
HIV Infections
Effects of TENS and Mindfulness Meditation in Persons With HIV-related Neuropathy
This study is to explore the effects of transcutaneous nerve stimulation (TENS) and mindfulness meditation in persons living with HIV (PLHIV) and painful neuropathy in the feet.
- Trial name
- NCT04868123
- Testing
- Transcutaneous Nerve Stimulation (TENS), Mindfulness Meditation
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Rutgers University
Transcranial Magnetic Stimulation, Complex Regional Pain Syndrome of Upper Limb (Disorder)
CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation
This is a sham controlled, randomized, double-blind, navigated repetitive Transcranial Magnetic Stimulation (nrTMS) study for the treatment of complex regional pain syndrome (CRPS types 1 and 2).
- Trial name
- NCT04439669
- Testing
- Active nrTMS and open phase
- Where
- 2 sites in Finland
- Volunteers
- 62 people
- Sponsor
- Helsinki University Central Hospital
Lumbosacral Radiculopathy
Procedural Framing and Epidural Steroid Injection Outcomes
Back pain is the leading cause of disability and military medical boards across the globe. Epidural steroid injections (ESI) are the most commonly performed pain procedure in the world.
- Trial name
- PEACE (NCT07498140)
- Testing
- Behavioral manipulation of ESI expectations, No behavioral manipulation of ESI expectations, No behavioral manipulation of pharmacotherapy expectations
- Where
- 4 sites in United States, Thailand and 1 more
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Lumbar Radiculopathy
Effects of Adding Balneotherapy to a Physical Therapy Program in Patients With Chronic Lumbar Radiculopathy
The aim of this study is to investigate the effects of adding balneotherapy to the conventional physical therapy program on neuropathic pain, disability, daily living activities, and sleep quality in patients with chronic lumbar…
- Trial name
- NCT06846970
- Testing
- Experimental, Active Comparator
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Afyonkarahisar Health Sciences University
HIV Infections, Peripheral Neuropathy
Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy
Study to determine if pregabalin is more effective than placebo in treating subjects with nerve pain associated with HIV neuropathy.
- Trial name
- NCT00232141
- Testing
- pregabalin
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 302 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postoperative Pain
Effectivness of Tramadol or Topic Lidocaine on Postoperative Analgesia in Laparoscopic Colorectal Resection.
Comparison of different postoperative analgesia after laparoscopic colorectal surgery
- Trial name
- NCT05831761
- Testing
- Comparison of analgesic efficacy protocol
- Volunteers
- 83 people
- Sponsor
- University Medical Centre Ljubljana
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