Clinical trials: Peripheral Neuropathy Pain
Herpes Zoster, Postherpetic Neuralgia
Shingles Prevention Study
The incidence and severity of HZ (or shingles), as well as the frequency and severity of its complications, increases markedly with increasing age. More than half of all cases occur in persons over the age of 60.
- Trial name
- SPS (NCT00007501)
- Testing
- Varicella-zoster vaccine
- Where
- 22 sites in United States
- Volunteers
- 38,456 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Carpal Tunnel Syndrome (CTS)
Median Nerve Thickness of the Carpal Tunnel Syndrome After Two Different Physiotherapy Modalities
The study plans to include a total of 60 patients diagnosed with carpal tunnel syndrome. Patients will be divided into two groups according to the treatment they receive.
- Trial name
- NCT07167667
- Testing
- Paraffin Bath, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Emre Şenocak
Postherpetic Neuralgia ( PHN ), Ultrasound Guided, Block, Ultrasound Guided Injection
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study
Postherpetic neuralgia (PHN) is a chronic pain syndrome that can be resistant to treatment, leading to physical and social disability, psychological disturbances, and potentially persisting for years .
- Trial name
- pain (NCT07067892)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Carpal Tunnel Syndrome, Susceptibility to
Non-surgical Intervention for Carpal Tunnel Syndrome
This randomized controlled trial graduate student research study will explore the effect of non-surgical intervention of the dorsal application of Kinesio Tape for carpal tunnel syndrome, and forearm wrist hand pain.
- Trial name
- NCT03360344
- Testing
- Kinesio 12 inch Tape, Kinesio 4 inch Tape, Cock up Splint and Lumbrical exercises
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Cervical Radiculopathy
Transcutaneous Electrical Nerve Stimulation Versus Repetitive Transcranial Magnetic Stimulation on Pain and Functional Outcome in Cervical Radiculopathy
this study will be conducted to compare between transcutaneous electrical nerve stimulation versus repetitive transcranial magnetic stimulation on pain and functional outcome in cervical radiculopathy
- Trial name
- CR (NCT07557511)
- Testing
- Transcutaneous Electrical Nerve Stimulation, repetitive Transcranial Magnetic Stimulation
- Volunteers
- 50 people
- Sponsor
- Cairo University
Radiculopathy, Sciatica
Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Double-blind, crossover, randomized, 3x3 Latin square, placebo-controlled study of single intravenous dose administration of VVZ-149. To demonstrate assay sensitivity, lidocaine will be administered as a positive control.
- Trial name
- LMR (NCT02644421)
- Testing
- VVZ-149, Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Carpal Tunnel Syndrome (CTS)
Combined Effects of Neurodynamics With PNF on Pain and ROM in Patients With CTS.
The goal of this clinical trial is to determine the combined effects of neurodynamics with proprioceptive neuromuscular facilitation technique on reducing pain and improving range of motion in patients with carpal tunnel…
- Trial name
- NCT07573878
- Testing
- Neurodynamic and PNF, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Back Pain, Lower Back Pain
Naltrexone and Clonidine Combination (ATNC05) in the Treatment of Chronic Back Pain
The study includes back pain of the cervical, thoracic, and the lumbar regions.
- Conditions
- Back Pain, Lower Back Pain, Cervical Pain
- Trial name
- NCT01415895
- Testing
- Naltrexone and Clonidine Combination
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Annette C. Toledano MD
Lumbar Radiculopathy
Mckenzie Technique vs Conventional Therapy in Correcting Lateral Shift in Chronic Lumber Radiculapthy Patient
Radiculopathy or nerve root pain arises from disc herniation, spinal stenosis/post-operative scarring, radiating down the leg in a dermatomal pattern.
- Trial name
- NCT07080047
- Testing
- Mackenzie exercise for lateral shift, Traditional physical therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Neuralgia
Ketamine and fMRI for Neuropathic Pain
Neuropathic or nerve injury related pain (NP), an extremely unpleasant condition that is difficult to treat, often has a severe, persistent, and unremitting course. Conventional treatments are often ineffective in relieving NP.
- Trial name
- NCT02373449
- Testing
- RS-fMRI, Ketamine
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- University Health Network, Toronto
Chemotherapy-induced Peripheral Neuropathy (CIPN), Acupuncture
Efficacy of Acupuncture on Chemotherapy-Induced Peripheral Neuropathy (CIPN)-TMANH
This three-armed, multicenter, randomized, parallel, sham-controlled clinical trial will conduct in three centers in Taiwan. The investigators will randomly assign 234 eligible patients into three groups, an acupuncture group…
- Trial name
- AcuCIPN (NCT07693335)
- Testing
- Acupuncture, Minimal acupuncture
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Carpal Tunnel Syndrome (CTS), Muscle Stiffness
Immediate Effects of Paraffin Wax Therapy on Forearm and Hand Muscle Stiffness and Pain in Carpal Tunnel Syndrome
This randomized controlled trial aims to investigate the immediate effects of paraffin wax therapy on muscle stiffness and pain among patients diagnosed with Carpal Tunnel Syndrome (CTS).
- Trial name
- Paraffin-CTS (NCT07260448)
- Testing
- Paraffin Wax Therapy, Rest Period (No Treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Erzurum Technical University
Peripheral Nerve Disorder Associated With Repair of Hernia
The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair
A common source of morbidity after IHR is chronic groin pain(CGP), usually defined as pain lasting longer than 3 months. Gabapentin is an anticonvulsant that is also of benefit in the treatment of neuropathic pain.
- Trial name
- NCT02419443
- Testing
- Gabapentin
- Volunteers
- 100 people
- Sponsor
- United States Naval Medical Center, San Diego
Pain, Chronic Pain
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury
Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain.
- Conditions
- Pain, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- TBI-Pain (NCT07424248)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Pain, Diabetic Neuropathies
A Phase 2 Study of Tapentadol Extended-Release (JNS024ER) ) in Japanese Participants With Chronic Pain Due to Diabetic Neuropathic Pain or Postherpetic Neuralgia
The purpose of this study is to investigate the efficacy and safety of tapentadol extended-release (ER) tablets in Japanese participants with moderate to severe chronic (lasting a long time) pain due to painful diabetic…
- Conditions
- Pain, Diabetic Neuropathies, Neuralgia, Postherpetic Neuralgia
- Trial name
- NCT01124617
- Testing
- Tapentadol
- Where
- 31 sites in Japan
- Volunteers
- 91 people
- Sponsor
- Janssen Pharmaceutical K.K.
Pain, Acute, Pain, Chronic
Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
Postoperative pain after thoracic surgery is associated with adverse outcomes. The current strategy to prevent postoperative pain is the use of regional anesthesia and analgesic agents.
- Conditions
- Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT03280017
- Testing
- Ketamine, Normal saline
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Neuralgia, Postherpetic
Lamictal in the Treatment of Post-Herpetic Neuralgia
To assess the efficacy of Lamictal for the treatment of pain and reduction of allodynia in patients with post herpetic neuralgia.
- Trial name
- NCT00295776
- Testing
- Lamictal in the treatment of Post-Herpetic Neuralgia
- Where
- United States
- Sponsor
- George Washington University
Chronic Neuropathic Pain
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
This research is being done to study a possible treatment for refractory pain due to small fiber neuropathy (SFN). ST-503 is intended to deliver a modified copy of the gene which will ideally repress Nav1.7 tissue-related pain…
- Trial name
- NCT06980948
- Testing
- ST-503
- Where
- 11 sites in United States
- Volunteers
- 27 people
- Sponsor
- Sangamo Therapeutics
Painful Diabetic Neuropathy
Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic Neuropathy
The purpose of this post-market study is to evaluate changes in pain and neurological function with high frequency, 10 kHz spinal cord stimulation (SCS) therapy in patients with chronic, intractable lower limb pain associated…
- Trial name
- PDN-SENSORY (NCT05777317)
- Testing
- 10 kHz SCS, CMM alone
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- Nevro Corp
Complex Regional Pain Syndromes
Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)
Pain remains the most debilitating symptom for adult patients suffering from complex regional pain syndrome (CRPS). Most CRPS patients gain little to no relief from current painkillers.
- Trial name
- NCT00689585
- Testing
- Ethosuximide
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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