Clinical trials: Peripheral Neuropathy With Type 2 Diabetes
Diabetic Neuropathy With Neurologic Complication
Balance Training in Diabetic Neuropathy
This study evaluates the efficacy of balance training in Diabetic Neuropathy. Control group will receive general exercises while Eperimental/ Interventional group will receive Balance exercises along with general exercises.
- Trial name
- NCT04232995
- Testing
- Balance Training, General Exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Pathologic Processes, Diabetes Mellitus
Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
The purpose of the study is to evaluate the efficacy of multiple human placental membrane products and Standard of Care (SOC) versus SOC alone in the management of nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers…
- Conditions
- Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases
- Trial name
- C5CAMP (NCT06674980)
- Testing
- Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- C5 Biomedical
Diabetic Peripheral Neuropathy Type 2
Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy
Background: Diabetic peripheral neuropathy (DPN) is a common and disabling chronic microvascular complications in patients with type 2 diabetic Mellitus (T2DM) that is characterized by nerve damage, affecting at least half of…
- Trial name
- NCT04711980
- Testing
- Mudan granule
- Where
- China
- Volunteers
- 402 people
- Sponsor
- Fengmei Lian
Diabetic Neuropathy
Alpha Lipoic Acid for Treatment of Diabetic Neuropathy
Patients with diabetic neuropathy and total symptoms score(TSS) >7 points were invited to this open multicenter study. Patients were free of pain medications and severe diabetic complications .Patients started alpha lipoic acid…
- Trial name
- NCT02439879
- Testing
- Alpha lipoic acid
- Volunteers
- 45 people
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Polyneuropathy
Asian Study on Cilostazol Effectivity in Neuropathies of Diabetes Mellitus Type 2-A Pilot Study in the Philippines
To describe if there are differences in the subjective, objective and electrophysiologic parameters of diabetic polyneuropathies at baseline, four (4) weeks, eight (8) weeks, and twelve (12) weeks after Cilostazol therapy.
- Trial name
- ASCEND (NCT01076478)
- Testing
- Cilostazol
- Where
- Philippines
- Volunteers
- 47 people
- Sponsor
- Otsuka Pharmaceutical, Inc., Philippines
Painful Diabetic Neuropathy, Diabetes Mellitus
A 12-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Painful Peripheral Neuropathy
This is a 12 week, 2-arm, blinded, single-site, placebo-controlled Phase II study in subjects with Type II Diabetes and painful peripheral neuropathy.
- Trial name
- NCT04786340
- Testing
- Active: WST-057 4mL (146 mg pirenzepine free base monohydrate) topical solution
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- WinSanTor, Inc
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Diabetic Foot Ulcer (DFU), Diabetic Symmetrical Polyneuropathy
Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound Healing
Diabetic symmetrical polyneuropathy (DSPN) is a common complication of diabetes that affects the nerves, especially in the legs and feet. It can cause pain, numbness, tingling, weakness, and loss of sensation.
- Trial name
- NCT07877948
- Testing
- Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E, Vitamin B1, Vitamin B6, Vitamin B12
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- BREGO Life Sciences
Peripheral Neuropathy With Type 2 Diabetes
Frequency Rhythmic Electrical Modulated Stimulation Effect in Peripheral Neuropathy Patients Severity of Cases and Qol.
It's estimated that 50% of diabetic patients will have peripheral neuropathy as a complication within 3 years of the diabetes incidence [14], the goal of the study is to investigate this problem through the following objectives…
- Trial name
- FREMS (NCT07645482)
- Testing
- frequency rhythmic electrical modulated stimulation., Duloxetine - low dose
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Diabetic Peripheral Neuropathy Type 2
Concurrent Training vs Soleus Push-Ups on Neurogenesis-Related Biomarkers in Diabetic Neuropathy Patients
This study will examine how two types of exercise programs affect nerve health in people with diabetic peripheral neuropathy. Diabetic peripheral neuropathy is a common complication of type 2 diabetes that can cause numbness…
- Trial name
- NCT07675720
- Testing
- Concurrent Training, Soleus Push-ups
- Where
- Pakistan
- Volunteers
- 99 people
- Sponsor
- Riphah International University
Neuropathy, Diabetic
Relaxation and Meditation Techniques on Pain, Fatigue and Quality of Life
Patients with painful diabethic peripheral neuropathy will be entered.. Participants will be randomized to one of three study arms: Arm 1: relaxatio; Arm 2:meditation Arm 3: Attention matched control Hypothesis: Progressive…
- Trial name
- NCT04287439
- Testing
- Progressive muscle relaxation, Mindfulness meditation, Attention matched control
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Hacettepe University
Diabetic Foot Ulcer, Diabetic Neuropathy
Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds
The primary purpose of this study is to determine the degree of loss of epidermal nerve fibers near a foot wound in patients with diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer, Diabetic Neuropathy, Type 2 Diabetes
- Trial name
- NCT02347709
- Testing
- Diabetic Foot Ulcer Biopsy, Survey, Comprehensive Neuropathy Assessment
- Where
- United States
- Sponsor
- Winthrop University Hospital
Diabetes Mellitus, Neuropathy
Diabetic Neuropathy in Spinal Cord Stimulator Patients
The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic…
- Conditions
- Diabetes Mellitus, Neuropathy, Neuropathic Pain, Vascular Diseases
- Trial name
- NCT04687215
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Chicago
Diabetic Neuropathies
Role of Synchronized Lifestyle Modification Program in Insulin Dependent Diabetic Peripheral Neuropathy Patients
This study aims to determine the role of Synchronized Lifestyle modification program along with Physiotherapy on the symptoms of DPN in patients on insulin therapy.
- Trial name
- NCT04813133
- Testing
- Synchronized Lifestyle Modification Program, Synchronized Lifestyle Modification Program and Physiotherapy, Physiotherapy
- Where
- Pakistan
- Volunteers
- 216 people
- Sponsor
- Riphah International University
Diabetic Neuropathy
Evaluation of Rocker sOles in Diabetis
The purpose of this study is to determine if the wearing of shoes "rocker sole" type prescribed in type 2 diabetics patients with neuropathy are responsible for disorders of equilibrium.
- Trial name
- EROD (NCT02891928)
- Testing
- Rocker sole shoes, Normal shoes
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Brest
Cardiovascular Autonomic Neuropathy, Type 2 Diabetes
Finerenone Treatment for Diabetic Cardiovascular Autonomic Neuropathy: the FibroCAN Study
Diabetic neuropathy is a serious and common complication of diabetes that currently has no cure. One form of this condition is cardiovascular autonomic neuropathy (CAN), which affects about 20% of people with diabetes-an…
- Conditions
- Cardiovascular Autonomic Neuropathy, Type 2 Diabetes, Diabetic Neuropathies
- Trial name
- FibroCAN (NCT06906081)
- Testing
- Kerendia (Finerenone, BAY94-8862)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Peter Rossing
Diabetes Type 2, Diabetic Neuropathies
High vs Low Dose Vitamin D in Patients With Diabetic Peripheral Neuropathy
Aim. To assess the effect of different doses of vitamin D supplementation on peripheral neuropathy in patients with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Type 2, Diabetic Neuropathies, Vitamin D Deficiency
- Trial name
- NCT04377399
- Testing
- Vitamin D
- Where
- Russia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Myocardial Infarction, Diabetes Mellitus, Type 2
Aerobic Training in Post-MI Patients With DPN
Cardiac rehabilitation (CR) is categorized by the American College of Cardiology "class IA recommendation" in the management of patients with cardiovascular disease (CVD) including post-myocardial infarction (MI) patients, who…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
- Trial name
- NCT03913793
- Testing
- Exercise based-cardiac rehabilitation (EB-CR) program
- Volunteers
- 37 people
- Sponsor
- Yousra Hisham Abdel Fattah
Diabetic Polyneuropathy
Correlation of HbA1c With Electrophysiological Studies and Gait Performance in Diabetic Polyneuropathy Patients
This study will be conducted to investigate the relationship between glycosylated hemoglobin (HbA1c) and nerve conduction studies (NCS) with gait performance in patients with DPN.
- Trial name
- NCT05457192
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Shereen Saad Eldin Mohamed Ali