Clinical trials: Peripheral Perfusion, open to volunteers
Exposure to Man-made Visible Light
Peripheral Blood Flow Responses to Electromagnetic Energy
This study evaluates 670 nm energy in the form of red light to stimulate blood flow changes in healthy adults. All participants will receive red light to their leg.
- Trial name
- NCT02370199
- Testing
- 670 nm light, octafluropropane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sepsis, Critical Illness
Peripheral Perfusion Index Trajectory to Predict 28-Day Mortality in Patients With Sepsis in the Intensive Care Unit
Sepsis is a life-threatening condition caused by the body's overwhelming response to infection, and it remains a leading cause of death in intensive care units.
- Trial name
- PERFUSE-ICU (NCT07740304)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Trakya University
Perfusion Index, Weaning of Mechanical Ventilation
PPI in Weaning Prediction
The aim of this study is to evaluate the predictive role of the Peripheral Perfusion Index (PPI) in forecasting extubation success during the weaning process in intensive care unit (ICU) patients.
- Conditions
- Perfusion Index, Weaning of Mechanical Ventilation, ICU
- Trial name
- NCT07120672
- Testing
- patients were monitored for reentubation for 48 hours., weaning group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
HCM - Hypertrophic Cardiomyopathy, Anderson Fabry Disease
Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes
This observational study aims to evaluate myocardial perfusion abnormalities using quantitative and qualitative cardiac magnetic resonance (CMR) perfusion imaging in patients with hypertrophic cardiomyopathy (HCM) phenotypes…
- Conditions
- HCM - Hypertrophic Cardiomyopathy, Anderson Fabry Disease, Cardiac Magnetic Resonance Imaging, Amyloid Cardiomyopathy
- Trial name
- MyoPerf-HCM (NCT07382128)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Capillary Refill Time, Peripheral Tissue Perfusion
Smartphone Application for Automated Measurement of Capillary Refill Time (CRT)
This prospective, monocenter observational study aims to validate a smartphone application (CRTApp) that automatically measures capillary refill time (CRT) from a short video of a standardized finger compression.
- Trial name
- CRTApp (NCT07473869)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sedentary Behavior, Peripheral Circulation
Buerger-Allen Exercises and Peripheral Circulation in Sedentary Office Workers
This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers.
- Conditions
- Sedentary Behavior, Peripheral Circulation, Vascular Function
- Trial name
- BAE-CIRC (NCT07588893)
- Testing
- Buerger-Allen Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Peripheral Artery Disease (PAD), CT Perfusion
Clinical Value of CT Perfusion in Peripheral Artery Disease
Peripheral artery disease (PAD) affects millions worldwide and can lead to serious complications such as leg ulcers, gangrene, and amputation.
- Conditions
- Peripheral Artery Disease (PAD), CT Perfusion, Revascularization, Microcirculation
- Trial name
- iPAD (NCT07816757)
- Volunteers
- 200 people
- Sponsor
- Fudan University
Ageing, Muscle Fatigue Caused by Repetitive Muscle Exercise
The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction
The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes.
- Trial name
- NCT07090603
- Testing
- Knee extension exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Limb-Threatening Ischemia
Pressure Wire Guidance for Infrapopliteal Artery Interventions
"• A prospective, single-center randomized controlled comparison trial. A total of 100 patients with symptoms of chronic limb-threatening ischemia (Rutherford category 5) undergoing endovascular treatment for anterior tibial…
- Trial name
- NCT06879561
- Testing
- Angiography-guided angioplasty, Pressure wire-guided angioplasty
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Diabetic Foot Ulcer
Effect of Electromagnetic Field Therapy and Customized Foot Insole on Peripheral Circulation and Ankle-Brachial Pressure Index in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFUs) are a significant complication of diabetes mellitus, associated with poor peripheral circulation, neuropathy, and increased risk of lower-limb amputation.
- Trial name
- NCT07070544
- Testing
- Electromagnetic Field Therapy: • Frequency: 50 Hz • Intensity: 5-30 mT • Duration: 30 minutes/session • Frequency: 3 sessions/week for 8 weeks Customized Foot Insoles: • Individually tailored based on
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- South Valley University
Critical Illness, Low Peripheral Perfusion
Local Warming to Improve Pulse Oximetry Accuracy in Critically Ill Patients
Pulse oximeters are widely used in intensive care to continuously estimate the oxygen level in the blood. However, pulse oximeter measurements may be less accurate when blood flow to the fingers is poor, which is common in…
- Conditions
- Critical Illness, Low Peripheral Perfusion, Pulse Oximetry Accuracy
- Trial name
- PULSEWARM (NCT07792304)
- Testing
- Protocolized Local Warming
- Where
- 4 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Vastra Gotaland Region
SEPSIS, Septic Patients
Peripheral Perfusion and Outcomes in ICU Patients With Sepsis
People with sepsis who are treated in the intensive care unit (ICU) often have impaired blood flow to the skin and other tissues.
- Trial name
- PERFUSE-ICU (NCT07391098)
- Testing
- PERIPHERAL PERFUSION EVALUATION
- Where
- Romania
- Volunteers
- 80 people
- Sponsor
- Alexandra Elena Lazăr
Sepsis, Septic Shock
Peripheral Perfusion Index-guided Fluid Resuscitation for Preventing Acute Skin Failure in Elderly Critically Ill Patients
This prospective, randomized, controlled trial aimed to evaluate whether fluid resuscitation guided by the Peripheral Perfusion Index (PPI) could reduce the incidence of Acute Skin Failure (ASF) in elderly critically ill…
- Conditions
- Sepsis, Septic Shock, Acute Skin Failure
- Trial name
- PPI-PROTECT (NCT07367113)
- Testing
- Peripheral Perfusion Index-guided Fluid Resuscitation Protocol, Conventional Goal-Directed Fluid Resuscitation
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ying Wang
Blood Circulation, Peripheral Blood Flow
A Single-center, Randomized, Double-blind, Placebo-controlled, Intervention Clinical Trial to Evaluate the Efficacy and Safety of "KoreaGinseng F Max" on Blood Circulation Improvement in Adults With Poor Peripheral Blood Flow
This is a single-center, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of a white ginseng extract (KoreaGinseng F Max) for improving blood circulation in adults with poor…
- Conditions
- Blood Circulation, Peripheral Blood Flow, Platelet Aggregation
- Trial name
- NCT07643532
- Testing
- KoreaGinseng F Max
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Peripheral Arterial Disease
Augmentation of Limb Perfusion With Contrast Ultrasound
Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion.
- Trial name
- NCT03195556
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Labor Epidural Analgesia, Perfusion Index
Perfusion Index Variability During Epidural Labor Analgesia
This prospective, single-centre observational study evaluates changes in the peripheral Perfusion Index (PI) - a non-invasive parameter derived from the pulse-oximetry photoplethysmographic waveform - in women receiving epidural…
- Conditions
- Labor Epidural Analgesia, Perfusion Index, Pain
- Trial name
- NCT07831967
- Testing
- Epidural (or opioid-only combined spinal-epidural) labor analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Peripheral Arterial Disease, Critical Limb Ischemia
Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention
This is a preliminary prospective observational study measuring change in lower extremity temperature in response to revascularization procedure.
- Conditions
- Peripheral Arterial Disease, Critical Limb Ischemia, Critical Lower Limb Ischemia
- Trial name
- TIC (NCT06544135)
- Testing
- FLIR One Pro LT
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- University Hospitals Cleveland Medical Center