Clinical trials: Peripheral Pulmonary Lesions
Lung Cancer
CT-Controlled Advanced Navigation Techniques for Transbronchial Pulmonary Lesion Access; Evaluation of Electromagnetic Navigation Based Diagnostic Yield
In this clinical trial we will investigate the diagnostic yield of a combination of commercially available imaging and navigation techniques for reaching peripheral lung lesions.
- Trial name
- CONTROL-E (NCT03355586)
- Testing
- Electromagnetic navigation
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Lung Nodule
Tri-modality Sampling Using Radial Probe Endobronchial Ultrasound for the Diagnosis of Peripheral Pulmonary Lesions
As the former radial probe endobronchial ultrasound (RP-EBUS) guided transbronchial forceps biopsy of peripheral pulmonary nodules has some limitations, the purpose of this study is to investigate a novel biopsy technique that…
- Trial name
- NCT06123312
- Testing
- Tri-modality biopsy
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Pusan National University Hospital
Lung; Node
Robotic Bronchoscopy for Peripheral Pulmonary Lesions
In this study, the feasibility of performing robotic navigation of peripheral airways in human subjects for the purpose of biopsying peripheral lung lesions will be evaluated.
- Trial name
- NCT03727425
- Testing
- Robotic assisted bronchoscopy
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- Auris Health, Inc.
Lung Cancer
Utility of Endobronchial Ultrasound in the Investigation of Suspected Lung Cancer.
Bronchoscopy of non visible lesions in the lung, have a low diagnostic yield. The use of endoscopic ultrasound might increase the diagnostic yield.
- Trial name
- NCT00398970
- Testing
- Endobronchial ultrasound miniprobe
- Where
- Norway
- Volunteers
- 240 people
- Sponsor
- Haukeland University Hospital
Lung Cancer
Comparing Diagnostic Yield Between R-EBUS Guided Cryo Biopsy Vs. CT Guided Biopsy for PPL
Obtaining a tissue sample to diagnose a PPL suspected of cancerous origin is of utmost importance. The current gold standard; Transthoracic CT guided needle biopsy approach with a success rate of >90% comes at the expense of an…
- Trial name
- CT-CROP (NCT02395939)
- Testing
- CT guided core biopsy, Cryo-biopsy via Radial EBUS navigation
- Where
- New Zealand
- Volunteers
- 158 people
- Sponsor
- Middlemore Hospital, New Zealand
Peripheral Pulmonary Lesions
Study on the Influence of Fluoroscopy in the Diagnosis of Peripheral Lung Lesions With Endobronchial Ultrasound Guidance
The purpose of this study is to determine whether the use of fluoroscopy improves the diagnostic yield of peripheral pulmonary lesions' biopsy guided by radial endobronchial ultrasound (with the use of a guide sheath).
- Trial name
- NCT01863836
- Testing
- Fluoroscopy, Radial EBUS-guided biopsy
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- Laval University
Pulmonary Nodule
Feasibility and Safety of Remote Robotic Bronchoscopy System in Diagnosis of Peripheral Pulmonary Lesions: a Multicenter, Randomized Controlled, proof-of Concept Trial
Robotic bronchoscopy represents the latest localization technology for peripheral pulmonary nodules, enabling precise and stable manipulation and potentially improving the diagnostic yield of peripheral lung pathologies.
- Trial name
- NCT06613412
- Testing
- Remote Robotic Bronchoscopy system
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou Medical University
Lung Cancer
Evaluation of Deployment Capability and Accuracy of an Outside the Scope (OTS), Detachable Catheter System for Ablation of Peripheral Lung Lesions: An Ex-Vivo Human Lung Model Study
A novel OTS detachable probe system carried outside and along the flexible bronchoscope has been developed. Using this novel system, the operator can deploy the probe in the target bronchus and lesion and completely detach the…
- Trial name
- NCT04722432
- Testing
- Outside the Scope (OTS), Detachable Catheter System
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Nodules, Peripheral Lung Lesions
Shape-Sensing Robotic-Assisted Bronchoscopy for Diagnosis of Peripheral Pulmonary Nodules in Korea
What is this study about? This study tests a new robotic technology to take tissue samples from lung nodules (small spots in the lungs). Some lung nodules are cancer, but doctors need a tissue sample to know for sure.
- Conditions
- Lung Nodules, Peripheral Lung Lesions, Pulmonary Nodules, Lung Cancers
- Trial name
- ULSAN-ION (NCT07057648)
- Testing
- Shape-sensing Robotic-assisted Bronchoscopy (ssRAB)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ulsan University Hospital
Lung Ultrasound, Lung Cancer (Diagnosis)
3D-US Construct on Volumetric Assessment of Lung Disease & Clinical Application
The goal of this observational study is to establish the three-dimensional construct of lung lesion via ultrasound in patients with peripheral lung lesions or any superficial lesion in thoracic fields.
- Conditions
- Lung Ultrasound, Lung Cancer (Diagnosis), Peripheral Lung Lesions, Ultrasound Assessment
- Trial name
- NCT07574255
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer, Nodes, Lung
Confirmation of Accuracy of the Tool-in-lesion Technology (TiLT) of the Galaxy System With Integrated TOMO Technology
This study will evaluate the feasibility of performing robotic navigation of peripheral airways in human subjects for the purpose of biopsying peripheral lung lesions.
- Trial name
- TiLT (NCT06056128)
- Testing
- Robotic assisted bronchoscopy
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Noah Medical
Peripheral Lung Lesions
The Effectiveness and Safety of Electromagnetic Navigation Real-time Guided Percutaneous Lung Biopsy
The goal of this clinical trial is to evaluate the diagnostic efficacy and safety of percutaneous lung biopsy guided by electromagnetic navigation real-time positioning technology in peripheral lung lesions.
- Trial name
- NCT05799014
- Testing
- CT-guided percutaneous lung biopsy, Percutaneous lung biopsy guided by electromagnetic navigation real-time positioning technology
- Volunteers
- 200 people
- Sponsor
- China-Japan Friendship Hospital
Peripheral Pulmonary Lesions
Clinical Utility of Needle-Based Confocal Laser Endomicroscopy for Peripheral Pulmonary Lesions
This prospective, multicenter diagnostic accuracy study will evaluate the clinical utility of needle-based confocal laser endomicroscopy (nCLE) for differentiating malignant from benign peripheral pulmonary lesions (PPLs).
- Trial name
- NCT07827326
- Testing
- Confocal Laser Endomicroscopy
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Lung Cancer
UTB-VBN-EBUS With or Without Fluoroscopy for the Diagnosis of PPLs
The purpose of this study is to evaluate the feasibility,efficacy and safety of ultrathin bronchoscopy(UTB) combined with virtual bronchoscopic navigation(VBN) and endobronchial ultrasound(EBUS) for the diagnosis of peripheral…
- Trial name
- NCT02664259
- Testing
- VBN, EBUS, X-ray
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shanghai Chest Hospital
Peripheral Pulmonary Lesions
Feasibility of Thin Cp-EBUS Scope BF-UC290F for the Diagnosis of PPLs
The purpose of the study is to evaluate the diagnostic value and safety of Thin Convex Probe Endobronchial Ultrasound (TCP-EBUS) Scope for peripheral pulmonary lesions (PPLs)
- Trial name
- NCT05512533
- Testing
- Linear Ultrasound Bronchoscope BF-UC290F (Olympus)
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Shanghai Chest Hospital
Diagnoses Disease
Prediction Model of Peripheral Pulmonary Lesions Based on R-EBUS Image
Peripheral pulmonary lesions(PPLs) have a wide spectrum of diseases, and the diagnosis will affect the treatment strategy and prognosis.
- Trial name
- R-EBUS (NCT04497233)
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Shanghai Chest Hospital
Solitary Pulmonary Nodule, Biopsy, Fine-Needle
iNod System Human Feasibility Assessment
The purpose of this study is to demonstrate feasibility to access, visualize, and obtain specimens adequate for cytology of lung lesions in subjects with suspected lung cancer when using the iNod System.
- Trial name
- iNod (NCT02832284)
- Testing
- iNod System
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Boston Scientific Corporation
Pulmonary Nodule, Bronchoscopy
Comparative Performance of Robotic, Electromagnetic Navigation and Fluoroscopy Drives Optimal Diagnostic Strategy for Peripheral Pulmonary Lesions
Currently, the optimal method for Peripheral Pulmonary Lesions (PPL) is uncertain. We aim to compare the diagnostic yield of Robotic Bronchoscopy System (RBS), Electromagnetic Navigation Bronchoscopy (ENB)…
- Trial name
- NCT06701448
- Testing
- robotic bronchosopy, Electromagnetic Navigation Bronchoscopy, Fluoroscopy bronchoscopy
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Guangzhou Medical University
Lung Cancer
Conventional vs Ultrathin Bronchoscopy for Peripheral Pulmonary Lesions
This study's purpose is to evaluate whether the use of an ultra-thin bronchoscope can improve sensitivity and diagnostic yield in peripheral pulmonary nodules.
- Trial name
- NCT04029155
- Testing
- Lung biopsy
- Volunteers
- 142 people
- Sponsor
- Stefano Gasparini
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
iNod™ Ultrasound-Guided Needle Biopsy System Study
The purpose of this study is to collect information on the iNod™ System's safety and ability to see the iNod™ biopsy needle in real-time in endobronchial lesions, peripheral lung nodules, or lung masses.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Biopsy, Fine-Needle
- Trial name
- NCT05804435
- Testing
- iNod™ System
- Sponsor
- Boston Scientific Corporation