Clinical trials: Peripheral Vascular Disease (PVD)
Peripheral Arterial Disease, Intermittent Claudication
Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography
To systematically develop, test, and refine peripheral vascular electrocardiography-gated fast spin echo magnetic resonance imaging for the accurate diagnosis of peripheral arterial disease without gadolinium contrast.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
- Trial name
- NCT02823444
- Testing
- Magnetic Resonance Angiography
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tobacco Use Disorder
Smoking Termination Opportunity for inPatients
The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute smoking related illness, to assist patients through withdrawal by use of a…
- Trial name
- STOP (NCT01141855)
- Testing
- Champix, Counselling alone
- Where
- 3 sites in Australia
- Volunteers
- 392 people
- Sponsor
- The Queen Elizabeth Hospital
Phlebitis, NursİNG CARE
Phlebitis Experiences of Intensive Care Nurses
It is important to reveal the phlebitis experiences of nurses. The data obtained from the phlebitis experiences of nurses are important in terms of preventing phlebitis and supporting patient safety practices.
- Trial name
- NCT07051798
- Testing
- It is a qualitative type of study that will be conducted through face-to-face interviews.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Peripheral Artery Disease
Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease
This study was designed to assess the safety, tolerability and efficacy of ACZ885 on the leg artery structure and physical activity in patients with atherosclerotic peripheral artery disease and leg pain from walking.
- Trial name
- NCT01731990
- Testing
- Canakinumab (ACZ885)
- Where
- 14 sites in United States, Germany and 1 more
- Volunteers
- 38 people
- Sponsor
- Novartis Pharmaceuticals
Peripheral Vascular Disease
Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia
The purpose of this study is to assess the safety and feasibility of HBOC-201 in increasing adequate wound healing in patients with severe peripheral vascular disease who are undergoing lower limb amputation.
- Trial name
- NCT00300040
- Testing
- Hemoglobin glutamer 250 - bovine, 6% Hydroxyethylstarch
- Where
- 5 sites in South Africa, United Kingdom
- Volunteers
- 16 people
- Sponsor
- Biopure Corporation
Peripheral Artery Disease
Technical Development of Cardiovascular Magnetic Resonance Imaging
The goal of this study is to develop advances in cardiovascular diagnostic and treatment methods using magnetic resonance imaging (MRI), a test that uses a strong magnetic field and radio waves to show anatomic detail.
- Trial name
- NCT00064896
- Testing
- MRI
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stroke
Stroke - Sleep Disorders, Dysfunction of the Autonomic Nervous System and Depression
The purpose of this study is to investigate sleep disordered breathing, autonomic dysfunction, and post stroke depression in acute and chronic stroke patients.
- Trial name
- NCT02111408
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- Helle Klingenberg Iversen, MD, DmSc
Peripheral Vascular Disease, Claudication
Oral Nutritional Supplement in Reducing Surgical Site Infections
The study aims to evaluate the efficacy of an arginine enriched oral nutritional supplement in the prevention of wound complications in the the wounds of patients post lower limb revascularization.
- Trial name
- NCT02475525
- Testing
- Arginine enriched oral nutritional supplement
- Where
- Ireland
- Volunteers
- 6 people
- Sponsor
- University of Limerick
Peripheral Vascular Disease
Tack Optimized Balloon Angioplasty (TOBA) Study
A multi-center, post-CE Mark study designed to evaluate the performance of the Intact Vascular Tack-IT Endovascular Stapler™ in subjects with vascular flaps (e.g.; post-angioplasty dissection) resulting from percutaneous…
- Trial name
- TOBA (NCT01663818)
- Testing
- Tack-It Endovascular Stapler
- Where
- Belgium
- Volunteers
- 138 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Peripheral Vascular Diseases
A Clinical Investigation of SM-01 Stenting Versus PTA for the Treatment of Superficial Femoral Artery Disease
The main objective is to evaluate the safety and efficacy of SM-01 stenting (Cordis S.M.A.R.T.™ Nitinol Stent System) for the treatment of SFA lesions as compared to PTA (balloon angioplasty).
- Trial name
- NCT01183117
- Testing
- SM-01, PTA
- Where
- Japan
- Volunteers
- 105 people
- Sponsor
- Johnson & Johnson K.K. Medical Company
Peripheral Artery Disease
Microvascular Reactivity in Peripheral Artery Disease
Peripheral Artery Disease (PAD) is a major risk factor for lower limb amputation. Microvascular reactivity assessed with near-infrared spectrometry has been studied in people with PAD but not in people with limb loss (PLL) who…
- Trial name
- NCT05063474
- Testing
- No Intervention-Clinical Assessments only
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Columbia University
Peripheral Arterial Disease, Critical Limb Ischemia
Swedish Drug-elution Trial in Peripheral Arterial Disease
Peripheral arterial disease (PAD) causes reduced blood flow to the lower limb(s) due to stenosis or occlusion in the supplying arteries.
- Conditions
- Peripheral Arterial Disease, Critical Limb Ischemia, Intermittent Claudication
- Trial name
- SWEDEPAD (NCT02051088)
- Testing
- Revascularization with drug-eluting technology, Revascularization without drug-eluting technology, drug-coated balloons and/or drug-eluting stents
- Where
- Sweden
- Volunteers
- 3,556 people
- Sponsor
- Sahlgrenska University Hospital
Peripheral Artery Disease
Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease
Obstructive sleep apnea syndrome (OSAS) is characterized by partial (hypopnea) or complete (apnea) obstruction of the upper airways, leading to intermittent hypoxemia and sleep fragmentation.
- Trial name
- OSAPAD (NCT07283289)
- Where
- France
- Volunteers
- 295 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Heart Failure, Coronary Artery Disease
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study
This is a single-center, double-arm, open-label, randomized feasibility study that will determine whether a novel clinical decision aid accessed via the electronic health record will be acceptable to both cancer survivors and…
- Conditions
- Heart Failure, Coronary Artery Disease, Peripheral Artery Disease, Ischemia
- Trial name
- NCT05377320
- Testing
- Clinical Decision Aid, Standard Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical College of Wisconsin
Peripheral Arterial Disease
OEIS Outcome Data Registry
This registry is created under the sponsorship of the Outpatient Endovascular and Interventional Society (OEIS) to monitor the clinical course and treatment outcomes of patients undergoing office-based endovascular procedures.
- Trial name
- NCT03058913
- Where
- United States
- Volunteers
- 600,000 people
- Sponsor
- Outpatient Endovascular and Interventional Society
Superficial Femoral Artery Stenosis, Superficial Femoral Artery Occlusion
Revascularization With Open Bypass Versus Angioplasty and STenting of the Lower Extremity Trial (ROBUST)
This is a prospective randomized controlled trial to compare clinical improvement, cost effectiveness and patency rates between new and improved Nitinol stents and open bypass surgery in the superficial femoral artery disease.
- Conditions
- Superficial Femoral Artery Stenosis, Superficial Femoral Artery Occlusion, Claudication, Rest Pain
- Trial name
- ROBUST (NCT01602159)
- Testing
- Open Bypass Surgery, Angioplasty and Stenting
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Johns Hopkins University
Peripheral Arterial Disease
PAD Awareness Study
Peripheral arterial disease (PAD) is one of the most common cardiovascular diseases in developed countries [1] and is an emerging problem in developing countries [2, 3].
- Trial name
- NCT05552079
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Peripheral Arterial Disease
The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)
This research study will evaluate the effects of aspirin and dipyridamole alone and in combination on the blood flow in the vessels of the legs.
- Trial name
- NCT00906035
- Testing
- Dipyridamole 200mg and Aspirin 25mg bid:, Dipyridamole 200 mg bid, Aspirin 25 mg bid
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Pennsylvania
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor
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