Clinical trials: Peripheral Vascular Disease (PVD)
Atherosclerosis, Intermittent Claudication
Whole Body Magnetic Resonance Angiography in Ischemic Patients
To investigate the diagnostic performance of whole body magnetic resonance angiography (WB-MRA) using two different magnetic resonance contrast agents.
- Trial name
- NCT00538408
- Testing
- Whole body magnetic resonance angiography (dotarem), Whole body magnetic resonance angiography (vasovist)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Copenhagen University Hospital at Herlev
Chronic Limb-threatening Ischemia, Endovascular Therapy
Prospective Multicenter Registry on the Endovascular Treatment in Critical Limb Threatening Ischemia With Below the Knee Lesions With Wound, Ischemia, and Foot Infection (WIFI) Assessment
This is a prospective multicenter clinical study that used WIFI grading scores at different periods to evaluate the therapeutic value of endovascular therapy and this grading system for Chronic limb-threatening ischemia.
- Trial name
- NCT04710420
- Testing
- Endovascular therapy
- Where
- China
- Volunteers
- 842 people
- Sponsor
- Xuanwu Hospital, Beijing
Popliteal Artery Aneurysm, Peripheral Arterial Disease
Prospective Case-control Study in Patients With PAA
The overall objective is to highlight different aspects of care in patients with PAA before and after treatment, and identifying factors that influence the outcome of PAA patients.
- Conditions
- Popliteal Artery Aneurysm, Peripheral Arterial Disease, Quality of Life
- Trial name
- NCT04188808
- Testing
- Bypass surgery
- Where
- 2 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Rebecka Hultgren
Erectile Dysfunction, Peripheral Arterial Disease
Predicting Peripheral Arterial Disease in Men With Erectile Dysfunction
Erectile dysfunction is a common complaint and is found frequently in men with hyperlipidemia, hypertension, diabetes and those who smoke. ED may also be an early warning of peripheral arterial disease.
- Trial name
- PREPARED (NCT00743613)
- Testing
- Sexual Health Inventory for Men (SHIM), Ankle-Brachial Index (ABI)
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Bruton Avenue Family Practice
PAD - Peripheral Arterial Disease, Lumbar Spinal Stenosis
CLE-PAD : Prevalence of PAD in Patients With Surgically Lumbar Spinal Stenosis
The goal of this interventional study is to evaluate the rate of existing lower limb peripheral artery disease (PAD) in patients with surgically lumbar spinal stenosis (LSS).
- Conditions
- PAD - Peripheral Arterial Disease, Lumbar Spinal Stenosis, Lower Limb Arterial Disease
- Trial name
- CLE-PAD (NCT07469020)
- Testing
- contrast-enhanced CT scan
- Where
- 3 sites in France
- Volunteers
- 49 people
- Sponsor
- Rennes University Hospital
Peripheral Artery Disease (PAD); Intermittent Claudication
Study of LLG783 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication
This study is designed to determine whether LLG783 displays the clinical safety and efficacy profile, after multiple i.v. doses, to support further development in patients with PAD and intermittent claudication.
- Trial name
- PAD PoC (NCT03194776)
- Testing
- LLG783
- Where
- 8 sites in United States, Germany and 1 more
- Volunteers
- 46 people
- Sponsor
- Novartis Pharmaceuticals
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function.
- Trial name
- NCT06383390
- Testing
- Retatrutide
- Where
- 742 sites in United States, Argentina and 25 more
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Peripheral Artery Disease (PAD)
Use of Three-Dimensional Printed Models for Endovascular Planning and Follow-up in Patients Affected by Aorto-Iliac-Femoral-Popliteal Arterial Disease Undergoing Balloon Angioplasty. A Single-center, Single-blind Randomized Controlled Trial
Lower extremity peripheral arterial disease is a major health problem. Currently, balloon angioplasty represents the most commonly performed treatment for patients affected by vascular claudication or critical limb ischemia.
- Trial name
- 3DPAD-1 (NCT07000097)
- Testing
- PTA planning supported by 3D-printed model, PTA (Standard of Care)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Diabetes Complications, Peripheral Arterial Disease
Collaborative-care Rehabilitation After Dysvascular Amputation
The objective of this study is to examine the feasibility of using a collaborative-care, home-based rehabilitation program to improve functional outcomes for people recovering from lower limb amputation caused by vascular…
- Trial name
- NCT01929018
- Testing
- Exercise, Walking Program, Health Self-Management Support
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Peripheral Vascular Disease, Microcirculation
Evaluation of the Clinical Significance of Fluorescence Videoangiography With Indocyanine-Green
The aim of the study is to compare the diagnostic value of this non-invasive vascular imaging tool with the established vascular diagnostic methods for PAD in order to get prognostic data.
- Conditions
- Peripheral Vascular Disease, Microcirculation, Ischemia
- Trial name
- NCT00876668
- Volunteers
- 25 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Critical Limb Ischemia (CLI)
Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin
To study the effect of the stem cells therapy autologous mononuclear from the bone marrow, autologous progenitor endothelial CD133 cells from the bone marrow and autologous mesenchymal stem cells from adipose tissue on the…
- Trial name
- NCT02287974
- Testing
- Stem cell infusion
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Hemodialysis Patients, Peripheral Vascular Disease
Effects of Cilostazol on VEGF and Oxidative Stress Biomarkers in Hemodialysis Patients With Peripheral Vascular Disease
Peripheral arterial disease (PAD) is the most common manifestation of systemic atherosclerosis and accounts for significant morbidity and mortality among end-stage renal disease (ESRD) patients.
- Trial name
- NCT00431249
- Testing
- Cilostazol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Peripheral Arterial Disease, Leg Ulcer
Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia
Peripheral arterial disease (PAD) can progress to critical limb ischemia (CLI) of the affected lower limb, characterized by pain at rest, ulcerations or gangrene, with a high risk of amputation.
- Trial name
- NCT06326203
- Testing
- CELULAS TRONCO, CONVENTIONAL DRESSING
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Peripheral Arterial Disease
a Physician-inititated Trial Investigating the iVolution Nitinol Stent
The objective of this clinical investigation is to evaluate the short-term (up to 12 months) outcome of treatment by means of the self-expanding iVolution nitinol stent in symptomatic (Rutherford 2-4) femoropopliteal arterial…
- Trial name
- NCT02430922
- Testing
- iVolution nitinol stent
- Where
- 4 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Flanders Medical Research Program
Peripheral Vascular Disease
Drug-Coated Chocolate PTA Balloon in Patients With Peripheral Arterial Disease - The ENDURE Trial
This first-in-man study is to evaluate the Drug-Coated Chocolate (DCC) Balloon for percutaneous arterial angioplasty in patients with symptomatic peripheral arterial disease.
- Trial name
- ENDURE (NCT02129127)
- Testing
- Paclitaxel Coated Chocolate Balloon Angioplasty
- Where
- 2 sites in Germany, New Zealand
- Volunteers
- 67 people
- Sponsor
- TriReme Medical, LLC
Critical Limb Ischemia (CLI)
LIFE-BTK PK Sub-study
LIFE-BTK PK is a prospective, single-arm, open-label, non-blinded, non-randomized sub-study of LIFE-BTK Randomized Controlled Trial (NCT04227899), that will enroll approximately 7 subjects in the United States (US) and outside…
- Trial name
- NCT05208905
- Testing
- Esprit BTK Device
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 9 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease, Peripheral Artery Disease
Implementation of Telemedicine for Patient With Lower Extremity Wounds
The objective of this study is to determine if patients with lower extremity wounds in rural communities who undergo specialty referral through telemedicine have expedited care compared to patients who are treated through…
- Conditions
- Peripheral Arterial Disease, Peripheral Artery Disease, Peripheral Vascular Diseases, Diabetic Foot
- Trial name
- NCT04440839
- Testing
- Telemedicine specialty consultation
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of California, Davis
Peripheral Artery Disease, Restenosis of Peripheral Vascular Stent
Hemostatic Endothelial Dysfunction in Patients With Peripheral Artery Disease
The study is aimed at evaluating the role of the activity of the key hemostatic parameters of endothelial dysfunction (nitric oxide II (NO) metabolites, plasmin activator inhibitor-1 (PAI-1), von Willebrand factor (vWF)…
- Conditions
- Peripheral Artery Disease, Restenosis of Peripheral Vascular Stent, Restenosis, Vascular Graft, Endothelial Dysfunction
- Trial name
- NCT04391374
- Testing
- an arterial reconstructive procedure
- Volunteers
- 167 people
- Sponsor
- Ryazan State Medical University
Diabetes Mellitus, Type 2, Peripheral Arterial Disease
REducing Diabetic MacrovascUlar Complications DuE to Peripheral Arterial Disease- REDUCE-PAD
This is a Phase IIa, multi-centre study conducted at 3 sites in Singapore (SGH and NUHS, KTPH). 70 patients with diabetes mellitus (DM) and peripheral arterial disease (PAD) will be randomised in a ratio 1:1 to receive normal…
- Trial name
- REDUCE-PAD (NCT05912218)
- Testing
- MEI6570
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- National Heart Centre Singapore
Peripheral Artery Disease, Intermittent Claudication
VascTrac Peripheral Arterial Disease (PAD) Study
VascTrac is a mobile medical application that tracks users' physical activity levels in order to predict endovascular failure of patients with Peripheral Artery Disease.
- Trial name
- VascTrac (NCT03048890)
- Testing
- Physical activity levels
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
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