Clinical trials: Peripheral Vascular Disease (PVD)
Peripheral Arterial Disease, Personal Satisfaction
CONTECI Program: A New Way to Control Peripheral Arterial Disease Using New Technologies
The current increase in chronic diseases calls for changes to the health system. It is necessary to promote expert patient in chronic disease.
- Conditions
- Peripheral Arterial Disease, Personal Satisfaction, Telemedicine
- Trial name
- NCT02762916
- Testing
- Selfmanage with the help of telemedicine program
- Volunteers
- 150 people
- Sponsor
- Consorci Sanitari del Maresme
Raynaud's Disease, Raynaud's Disease Secondary to Scleroderma
A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon
The purpose of this research study is to test the safety, tolerability, and effectiveness of Topical AmphiMatrix with Nitroglycerin (MQX0503) to relieve Raynaud's symptoms and increase blood flow to the fingers.
- Conditions
- Raynaud's Disease, Raynaud's Disease Secondary to Scleroderma, Raynaud's Disease Secondary to Other Autoimmune Disease
- Trial name
- NCT00577304
- Testing
- Nitroglycerin, Topical AmphiMatrix
- Where
- 17 sites in United States
- Volunteers
- 200 people
- Sponsor
- MediQuest Therapeutics
Ischemia, Peripheral Arterial Disease
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation
Patients undergoing semi-elective lower extremity major amputation from complications associated with atherosclerotic limb ischemia will received intra-muscular injections of allogeneic Mesenchymal Stromal Cells in the leg above…
- Conditions
- Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease, Vascular Disease
- Trial name
- CHAMP (NCT02685098)
- Testing
- Allogeneic bone marrow derived mesenchymal stem cells
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Indiana University
Peripheral Artery Disease
Validation of VascuQol-6 Spanish Version
VascuQol (VQ) is a specific questionnaire to assess the quality of life of patients with critical limb ischemia which is also used as an index in vascular registries.
- Trial name
- NCT04741321
- Testing
- VascuQol-6 questionnaire Spanish version
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Post Thrombotic Syndrome, Venous Thromboses
Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%.
- Conditions
- Post Thrombotic Syndrome, Venous Thromboses, Claudication, Intermittent
- Trial name
- ETERecaVSPT (NCT05794932)
- Testing
- Stress test
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Montpellier
Peripheral Arterial Disease, Arterio-venous Fistula
Serranator® Alto Post Market Clinical Follow Up (PMCF) Study
The objective of this registry is to collect observational data under local standard of care and evaluate safety and performance of the Serranator® Alto in treatment of peripheral artery disease (PAD), or dysfunctional native or…
- Conditions
- Peripheral Arterial Disease, Arterio-venous Fistula, Arteriovenous Graft
- Trial name
- NCT03538392
- Testing
- Serranator® Alto
- Sponsor
- Cagent Vascular LLC
Peripheral Vascular Diseases, Thrombosis
A Prospective Observational Registry of Peripheral Use of AngioJet Rheolytic Thrombectomy With Mid-Length Catheters
This registry collects observational data about how mid-length AngioJet catheters (ie XPEEDIOR and DVX models) are used in routine clinical practice.
- Conditions
- Peripheral Vascular Diseases, Thrombosis, Venous Thrombosis
- Trial name
- NCT00778336
- Volunteers
- 452 people
- Sponsor
- Boston Scientific Corporation
Peripheral Vascular Disease
RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty
This study aims to demonstrate if remote ischaemic preconditioning (RIPC) may confer renal protection in patients undergoing peripheral angioplasty.
- Trial name
- NCT02054871
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland
Peripheral Arterial Disease
Impact of Virtual Reality on Patient Pain During Lower Limb Revascularization Via Endovascular Surgery Under Local Anesthesia With Sedation
The prevalence of peripheral arterial disease (PAD) increases with age In addition to medical treatment, endovascular procedures can be performed, depending on the stage of the disease, to prevent complications and/or sequelae…
- Trial name
- REVDOU (NCT07181434)
- Testing
- The patient will be equipped with VR headsets
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Poitiers University Hospital
Peripheral Arterial Disease
SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs
A research project capturing experiences of patients with critical limb threatening ischemia, with the ultimate goal of setting new standards for diagnosing, describing detailed patient-centered outcomes, and evaluating the…
- Trial name
- SCOPE-CLI (NCT04710563)
- Where
- United States
- Volunteers
- 458 people
- Sponsor
- Yale University
Peripheral Artery Disease
Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities
The purpose of study was to test whether rivaroxaban added to standard of care treatment, when compared to placebo, had the potential to reduce the incidence of the clinical events related to the clots and complications of the…
- Trial name
- VOYAGER PAD (NCT02504216)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 532 sites in United States, Argentina and 32 more
- Volunteers
- 6,564 people
- Sponsor
- Bayer
Peripheral Arterial Disease
Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME II)
The purpose of this study is to evaluate the safety and effectiveness of the Jetstream Atherectomy System for the treatment of Japanese patients with symptomatic occlusive atherosclerotic lesions in native superficial femoral…
- Trial name
- NCT03847233
- Testing
- Jetstream Atherectomy System
- Where
- 5 sites in Japan
- Volunteers
- 31 people
- Sponsor
- Boston Scientific Corporation
Peripheral Arterial Disease
Exoskeleton Variability Optimization
Exoskeletons, wearable devices that assist with walking, can improve mobility in clinical populations. With exoskeletons, it is crucial to optimize the assistance profile.
- Trial name
- NCT04338815
- Testing
- Exoskeleton Optimization, Endurance Evaluation
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
PAD - Peripheral Arterial Disease, PVD- Peripheral Vascular Disease
Electrical Stimulation as an Adjunctive Therapy to Increase Vascular Perfusion in People With PAD or PVD
The purpose of this study is to apply Avazzia micro-current stimulation to patients with chronic, non-healing wounds to determine if this therapy is effective in perfusion and bacterial measurements.
- Trial name
- NCT04313985
- Testing
- Tennant Biomodulator-Pro™ Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Stanford University
Peripheral Arterial Disease
Angiotensin-(1-7) in Peripheral Arterial Disease
Peripheral arterial disease (PAD) affects over 8 million individuals in the United States alone. This is a form of atherosclerosis in which plaques preferentially build up inside the arteries of the legs to limit blood flow.
- Trial name
- NCT03240068
- Testing
- Angiotensin 1-7, Saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center
Peripheral Arterial Disease (PAD)
Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia
The objective of this prospective, multi-center, single arm study is to obtain further data on the safety and performance of the Drug-coated Balloon catheters in the treatment of the Superficial Femoral Artery (SFA) and Popliteal…
- Trial name
- UltraFuture I (NCT05498740)
- Testing
- Drug eluting Balloon
- Where
- 24 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Zylox Medical Device Co., Ltd.
Coronary Artery Disease, Hypertension
Acute Probiotic Supplementation and Endothelial Function
One in every two deaths in the United States is caused by cardiovascular disease. Despite strong mechanistic links established between a diet rich in lipids and the pathogenesis of cardiovascular disease, therapeutic advances…
- Conditions
- Coronary Artery Disease, Hypertension, Hyperlipidemias, Peripheral Vascular Diseases
- Trial name
- NCT04364074
- Testing
- Goodbelly
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Medical College of Wisconsin
Femoral Artery Stenosis, Popliteal Artery Stenosis
MDT-2113 Drug-Eluting Balloon vs. Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery and/or Proximal Popliteal Artery
The purpose of this trial is to assess the safety and efficacy of MDT-2113 for the interventional treatment of de novo and non-stented restenotic lesions in the superficial femoral artery (SFA) and the proximal popliteal artery…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- MDT-2113 SFA (NCT01947478)
- Testing
- MDT-2113 Drug-Eluting Balloon, Standard angioplasty balloon
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic Endovascular
Cardiovascular Diseases, Heart Diseases
Framingham Heart Study
The Framingham Heart Study was initiated to study the factors associated with the development of cardiovascular disease by employing long-term surveillance of an adult population in Framingham, Massachusetts.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00005121
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Peripheral Arterial Disease (PAD)
ULTRASCORE™ Focused Force PTA Balloon Angioplasty for CLI Patients With Below the Knee Vessel Disease
The purpose of this single-arm, exploratory study is to evaluate safety and performance of treatment of critical limb ischemia (CLI) with the ULTRASCORE™ Focused Force balloon.
- Trial name
- NCT04631848
- Testing
- ULTRASCORE™ Focused Force PTA Balloon
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Michael Lichtenberg, MD
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