Clinical trials: Peritonitis
Fecal Peritonitis, Secondary Peritonitis
Vacuum Assisted Closure Versus On-demand Relaparotomy in Patients With Fecal or Diffuse Peritonitis
Multicenter randomized controlled trial including patients with fecal or diffuse peritonitis to either vacuum assisted closure or relaparotomy "on-demand".
- Conditions
- Fecal Peritonitis, Secondary Peritonitis, Diffuse; Peritonitis
- Trial name
- VACOR (NCT03932461)
- Testing
- Vacuum assisted closure, Relaparotomy "on demand"
- Where
- Denmark
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Peritoneal Dialysis-associated Peritonitis, Peritoneal Dialysis (PD)
Pharmacokinetics of Intraperitoneal and Intravenous Meropenem, Ampicillin, Aztreonam and Ciprofloxacin in Automated Peritoneal Dialysis Patients Without Peritonitis
This study aims to investigate the pharmacokinetics (PK) and pharmacodynamic (PD) profiles of four commonly used antibiotics - meropenem, ampicillin, aztreonam, and ciprofloxacin - administered via intravenous (i.v.) and…
- Conditions
- Peritoneal Dialysis-associated Peritonitis, Peritoneal Dialysis (PD), Pharmacokinetics, Intravenous Administration
- Trial name
- NCT07113587
- Testing
- Application of intraperitoneal and intravenous meropenem in in automated peritoneal dialysis patients without peritonitis, Application of intraperitoneal and intravenous ampicillin in automated peritoneal dialysis patients without peritonitis, Application of intraperitoneal and intravenous aztreonam in automated peritoneal dialysis patients without peritonitis
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karl Landsteiner Insitute for Nephrology and Haemato-Oncology
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Peritoneal Dialysis-associated Peritonitis
Clinical Trial on Antibiotic-Lock in Tenckhoff Catheter for Relasping and Repeat Peritonitis
Biofilm formation is an important cause of catheter-related infection. In hemodialysis, use of an antibiotic-lock has been proven to be effective to manage such a complication with preservation of the central venous catheter.
- Trial name
- NCT05971537
- Testing
- antibiotic lock, conventional IP antibiotics
- Where
- Hong Kong
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Alice Ho Miu Ling Nethersole Hospital
Spontaneous Bacterial Peritonitis
Rifaximin as a Prophylaxis of Spontaneous Bacterial Peritonitis in Comparison With Ciprofloxacin
The goal of this Randomized controlled trial is to assessment the efficacy of Rifaximin as a prophylaxis of SBP in comparison with ciprofloxacin in Egyptian patients.
- Trial name
- NCT06234046
- Testing
- Rifaximin 550Mg Tab, Ciprofloxacin 750 MG, ascitic fluid sample
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Appendicitis Without Peritonitis, Medical Emergencies
Immature Granulocyte [IG] Count and Percentage for Medical Treatment of Uncomplicated Acute Appendicitis
After appendectomy was first described by Mcburney in 1889, it has been the most practiced emergency surgery in the world with the lifetime incidence of acute appendicitis being 5%-25%.
- Trial name
- [IG] (NCT04462588)
- Testing
- Cipro 400 MG in 200 ML Injection, Flagyl I.V. RTU, appendectomy (open or laparascopic)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI
Acute Appendicitis, Acute Appendicitis With Rupture
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial…
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess
- Trial name
- NCT04947748
- Testing
- Oral versus intravenous administration of antibacterial treatment
- Where
- Estonia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- North Estonia Medical Centre
Infectious Peritonitis
Evaluation of Intravenous and Intraperitoneal Pharmacokinetics of Dalbavancin in Peritoneal Dialysis Patients
This study will evaluate the pharmacokinetic properties of dalbavancin when administered as an intravenous infusion and instilled into the peritoneal space in patients who are undergoing peritoneal dialysis.
- Trial name
- NCT02940730
- Testing
- Dalbavancin via Intravenous Administration, Dalbavancin via Intraperitoneal Administration
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ascites, Peritonitis
Bedside Inoculation of Ascitic Fluid in Diagnostic Paracentesis
This study seeks to determine non inferiority of direct inoculation of ascitic fluid in lab as compared to current culture media standard, bedside inoculation with blood culture bottles.
- Trial name
- NCT02895919
- Testing
- Culture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cirrhosis of the Liver, Ascites
Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With Decompensated Cirrhosis With Ascites
This protocol represents an open-label pilot study to assess whether oral administration of SBI in subjects with decompensated cirrhosis with ascites can lead improvements in the management of the disease.
- Conditions
- Cirrhosis of the Liver, Ascites, Spontaneous Bacterial Peritonitis
- Trial name
- NCT02608658
- Testing
- Medical food, EnteraGam (Serum-Derived Bovine Immunoglobulin)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Tuberculosis
Treatment Duration for Abdominal Tuberculosis
Most of the guidelines on the treatment of tuberculosis suggest that 6 months treatment is sufficient for extrapulmonary tuberculosis except for bone tuberculosis and tubercular meningitis.
- Trial name
- RNTCP-DOTS (NCT01124929)
- Testing
- RNTCP Category I treatment for 6 months, RNTCP Category I treatment for 9months
- Where
- India
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Peritonitis
Pedicled Seromuscular Flap For Enforcement Of High Risk Intestinal Anastomoses
This is a control matched prospective study evaluating the use of seromuscular flap for high risk anastomoses.
- Trial name
- NCT01391169
- Testing
- seromuscular flap enforcement
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University