Clinical trials: Peroneal Neuropathy
Spinal Muscular Atrophy, Charcot-Marie-Tooth Disease
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder…
- Conditions
- Spinal Muscular Atrophy, Charcot-Marie-Tooth Disease, Muscular Dystrophy, Spinal Muscular Atrophy With Respiratory Distress 1
- Trial name
- NCT02532244
- Testing
- sample collection
- Where
- 3 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Peripheral Nervous System Diseases, Gait Disorders, Neurologic
Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or orthopedic injury.
- Conditions
- Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Foot Drop, Mobility Limitation
- Trial name
- NCT03530592
- Testing
- Seated Ankle Robot Training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Foot Drop, Unspecified Foot
Comparison of Gait in Different Support Conditions for Foot Drop
Foot drop is a complication accompanying a variety of conditions and refers to difficulty in lifting the foot upwards about the ankle.
- Trial name
- NCT05587010
- Testing
- AFO, lycra sock, OrthPed splint
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Dr Tim Exell
Foot Drop, Stroke
TREAT Foot Drop After Stroke With Ankle Robot
Researchers at the University of Maryland Rehabilitation and Orthopaedic Institute are looking for individuals who have suffered a stroke and have leg and ankle weakness (foot-drop), to participate in a pilot study to examine the…
- Conditions
- Foot Drop, Stroke, Hemiparesis
- Trial name
- TREAT (NCT04137809)
- Testing
- AMBLE
- Where
- United States
- Sponsor
- NextStep Robotics Inc.
Neuropathy, Peroneal, Motor Neuropathy
Neuromuscular Electrical Stimulation Versus Low-intensity Laser on Motor Conduction Velocity of the Common Peroneal Nerve Post Burn
Purposes of this study were the following: 1. To evaluate the therapeutic efficacy of NMES in improving the motor conduction velocity (MCV) of the neuropathic common peroneal nerve post burn. 2.
- Conditions
- Neuropathy, Peroneal, Motor Neuropathy, Neuromuscular Electric Stimulation (NEMS), Low Intensity Laser
- Trial name
- NCT06478914
- Testing
- Neuromuscular electrical stimulation (NMES), low-intensity laser therapy (LILT)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Stroke
Interactive Exoskeleton Robot for Walking
A new lower-limb training system is introduced to enhance the clinical service for post-stroke lower limb rehabilitation and to assist the establishment of public clinical trial in different settings and share experiences on the…
- Trial name
- NCT03184259
- Testing
- Robotic ankle system, Robotic knee system
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Peroneal Nerve Entrapment
Follow-up and Outcome of Operative Treatment With Decompressive Release Of The Peroneal Nerve
The FOOT DROP trial is a prospective, multi-center, randomized controlled trial to assess if decompressive surgery for peroneal nerve entrapment is superior to maximal conservative treatment.
- Trial name
- FOOTDROP (NCT04695834)
- Testing
- Neurolysis peroneal nerve, Maximal physiotherapy
- Where
- 18 sites in Belgium, Netherlands
- Volunteers
- 182 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Multiple Sclerosis, Foot Drop
Walking With FES or AFO in People With MS With Foot Drop
This investigation consists of two parallel groups of participants who will follow the same protocol. The aim of the study is to investigate the effects of using Functional Electrical Stimulation/Ankle Foot Orthosis (AFO) or…
- Trial name
- NCT01977287
- Testing
- Functional Electrical Stimulation, Ankle Foot Orthosis
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen Margaret University
Falls, Foot Drop
Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop
This study aims to determine if combining the treatments of transcranial direct current stimulation (tDCS) and functional electrical stimulation (FES) will better help persons with stroke who have difficulty lifting their toes.
- Conditions
- Falls, Foot Drop, Post Stroke Recovery
- Trial name
- tDCS (NCT07592221)
- Testing
- Standard protocol for combo of FES and tDCS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Saint Joseph's University, Philadelphia
Foot Drop
Augmenting Gait in a Population Exhibiting Foot Drop With Adaptive Functional Electrical Stimulation
The objective of this study is to investigate the effects of personalized, adaptive, current-steering functional electrical stimulation (FES) of the lower leg to improve gait in people with foot drop.
- Trial name
- NCT05346640
- Testing
- Cionic Neural Sleeve
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cionic, Inc.
Peroneal Muscular Atrophy
Genetics of Charcot-Marie-Tooth Dystrophy and Related Diseases
This is a cross-sectional study to clarify the gene lineage distribution of CMT genes in CMT patients in my country, draw a frequency map of CMT gene distribution, and assist in determining the genetic diagnosis strategy of CMT…
- Trial name
- NCT04967716
- Testing
- basic information, venous blood test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Peroneal Neuropathy
Functional Strength Training and Kinesiotaping, With and Without Proprioceptive Neuromuscular Facilitation in Fibular (Peroneal) Neuropathy
Fibular neuropathy frequently manifests as foot drop, muscle weakness, altered gait, and sensory loss, all of which severely reduce mobility and quality of life.
- Trial name
- NCT07191301
- Testing
- Functional Strength Training, Kinesio Taping, and Proprioceptive Neuromuscular Facilitation, Functional Strength Training and Kinesio Taping
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Lahore
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Wound, Venous Leg Ulcer
Geko™ Cross Therapy Registry - Wound
The geko™ Cross Therapy REGISTRY - Wound is a prospective, observational, anonymised data collection Registry with no experimental treatment that will fulfil an unmet need for an observational Registry to provide long-term…
- Conditions
- Wound, Venous Leg Ulcer, Diabetic Foot Ulcer, Arterial Leg Ulcer
- Trial name
- CTR-Wound (NCT05007301)
- Testing
- geko device
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Firstkind Ltd
Focal Neuropathies, Carpal Tunnel Syndrome
Neuromuscular Ultrasound for Focal Neuropathies
The purpose of this study is to determine if a new diagnostic technique, called neuromuscular ultrasound, can improve our ability to diagnose focal nerve disease.
- Conditions
- Focal Neuropathies, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Median Neuropathy
- Trial name
- NCT01394822
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wake Forest University
Multiple Sclerosis
Targeted Lower Extremity Joint Training
The presence of foot drop limits normal gait. Our prior data has suggested that approximately 30% of MS patients have foot drop.
- Trial name
- NCT00765544
- Testing
- Anklebot, Lokomat
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Foot Drop, Acute Lymphoblastic Leukemia
The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop
This study is designed to see if children with acute lymphoblastic leukemia who have developed foot drop during treatment for their leukemia consume less oxygen when walking with or without an ankle brace designed to support…
- Trial name
- NCT01001390
- Testing
- AFO Device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Jude Children's Research Hospital