Clinical trials: Persian Gulf Syndrome
Persian Gulf Syndrome
Mindfulness-Based Stress Reduction for Gulf War Syndrome
This pilot study is a two arm randomized, controlled clinical trial that evaluated whether a standardized Mindfulness-Based Stress Reduction (MBSR) intervention reduces symptoms associated with Gulf War Syndrome (GWS) more…
- Trial name
- NCT01267045
- Testing
- Mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- US Department of Veterans Affairs
Gulf War Syndrome
Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex
The adverse impact of Gulf War Syndrome (GWS) on the health of veterans and on the resources of the VA Healthcare System underscores the need to resolve its underlying cause.
- Trial name
- NCT00956150
- Testing
- Lactulose Breath Test, Rifaximin
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Henry C. Lin, MD
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Gulf War Digestive Health Study
The purposes of this study are to estimate the burden of disease due to chronic gastrointestinal illness in PG veterans, to evaluate whether Small Bowel Bacterial Overgrowth (SBBO) is associated with chronic diarrhea in PG…
- Trial name
- NCT00680836
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- US Department of Veterans Affairs
Persian Gulf Syndrome, Chronic Sinusitis
Gulf War Illness Nasal Irrigation Study
The purpose of this study is to determine whether nasal irrigation with Xylitol or saline are effective in the treatment of chronic rhinosinusitis and fatigue symptoms associated with Gulf War Illness.
- Conditions
- Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
- Trial name
- GWINIS (NCT01700725)
- Testing
- Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Gulf War Syndrome, Chronic Fatigue Syndrome
Hyporeactivity and Gulf War Illness
This research project is a follow-up to the prior VA-funded study that found that chronic fatigue reported by many Gulf War veterans may be a symptom of dysfunctional cardiovascular stress response regulation.
- Conditions
- Gulf War Syndrome, Chronic Fatigue Syndrome, Post-Traumatic Stress Disorder
- Trial name
- NCT00100412
- Testing
- Graded dobutamine infusions, Graded phenylephrine injections, Psychosocial challenge involving socioevaluative public speaking
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Irritable Bowel Syndrome
Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome
The purpose of this study is to provide new information and to determine which kinds of brief, tolerable, experimental pain are affected by the drugs being studied in patients with irritable bowel syndrome, a disease that causes…
- Trial name
- NCT00100425
- Testing
- Viceral Perception Testing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Gulf War Syndrome
Telemedicine Treatment for Veterans With Gulf War Illness
Effective treatments have been developed to ameliorate symptom-related distress and reduce unnecessary healthcare utilization using cognitive-behavioral techniques (CBT) .
- Trial name
- NCT00129454
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Gulf War Syndrome
START & STOPP in GWI
Gulf War Illness (GWI) veterans were divided into 2 pathophysiological groups based on their orthostatic tachycardia responses after submaximal exercise.
- Trial name
- START (NCT03560830)
- Testing
- 2 submaximal exercise stress tests
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Gulf War Syndrome
Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome
The main goal of the proposed study is to critically evaluate a nonpharmacological and readily available therapy, cranial electrical stimulation (CES) using Alpha-Stim™, and to discover the brain function mechanisms underlying…
- Trial name
- NCT07151248
- Testing
- Cranial electrical/electrotherapy stimulation (CES)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Persian Gulf War Syndrome in Veteran
Gulf War 1 Veteran Healthcare Satisfaction
The purpose of this study is to investigate Gulf War 1 Veteran (GW1V) patient perceptions of, and satisfaction with, their VA primary care treatment, and physician effectiveness in delivering improved point of service, in the…
- Trial name
- NCT01703767
- Testing
- Provider Education Workshop
- Where
- 2 sites in United States
- Sponsor
- University of Utah
Gulf War Illness
Effects of Botanical Microglia Modulators in Gulf War Illness
The overall objective of this protocol is to test if Gulf War Illness (GWI) involves chronic inflammation that cannot be measured with typical techniques.
- Trial name
- NCT02909686
- Testing
- Boswellia Serrata, Curcumin, Epimedium
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Persian Gulf Syndrome, Mycoplasma Infections
Antibiotic Treatment of Gulf War Veterans' Illnesses
In 1990 and 1991, the U.S. deployed approximately 700,000 troops to the Persian Gulf to liberate Kuwait from Iraqi occupation. While there were few casualties associated with the Gulf War, many individuals returned from this…
- Trial name
- NCT00007735
- Where
- 27 sites in United States, Puerto Rico
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Gulf War Syndrome
Follow-up of Psychological and Neurocognitive Gulf War Outcome: Relation to Stress
This is the follow-up to an observational epidemiological study of psychological and neuropsychological outcomes of deployed and non-deployed Gulf War-era veterans.
- Trial name
- NCT00018707
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Persian Gulf Syndrome, Chronic Fatigue Syndrome
Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans
This study will provide symptomatic veterans with acupressure treatment and determine its effectiveness in fatigue relief and pain management for Gulf War Illness (GWI).
- Trial name
- NCT02075489
- Testing
- Acupressure treatment., Reiki
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Cleveland Clinic
Gulf War Syndrome
Glutamate Neuro-Excitotoxicity in GWI
The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness (GWI).
- Trial name
- GWI (NCT03342482)
- Testing
- Low-glutamate diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Gulf War Syndrome, Gulf War Illness
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
- Conditions
- Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain
- Trial name
- NCT04182659
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Veterans Medical Research Foundation
Gulf War Syndrome
Glutathione vs. Curcumin Clinical Trial
The investigator proposes to perform a phase I/II study comparing two nutraceuticals and placebo that target mediators identified in the investigator's prior dynamic modeling study of Gulf War Illness (GWI).
- Trial name
- Glutathione (NCT02848417)
- Testing
- Curcumin, Glutathione
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- South Florida Veterans Affairs Foundation for Research and Education
Gulf War Syndrome, Persian Gulf Syndrome
Mitochondrial Cocktail for Gulf War Illness
The purpose of this study is to develop preliminary evidence, such as effect size and variance estimates, to guide successful conduct of a properly-powered clinical trial to assess the benefit of a mitochondrial cocktail…
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorders
- Trial name
- NCT02804828
- Testing
- Individualized mitochondrial cocktail
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego