Clinical trials: Persistent
Sunscreening Agents
Sun Protection Factor Assay (338/2016)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- NCT02995109
- Testing
- BAY987521, SPF Control
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Neutropenia, Fever
MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)
This study is a double-blind, randomized study of MK0991 versus liposomal amphotericin B in the empirical treatment of pediatric patients (ages 2 through 17 years) who have an absolute neutrophil count (ANC) below 500/microliter…
- Trial name
- NCT00082537
- Testing
- caspofungin acetate, Comparator: AmBisome
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Neoplasms, Uterine Cervix, Metastatic Cervical Cancer
Pazopanib Plus Lapatinib Compared to Lapatinib Alone and Pazopanib Alone In Subjects With Metastatic Cervical Cancer
This study is being conducted to compare the efficacy and safety of pazopanib in combination with lapatinib with that of lapatinib alone or pazopanib alone in subjects with metastatic cervical cancer
- Trial name
- NCT00430781
- Testing
- pazopanib (GW786034), lapatinib (GW572016)
- Where
- 63 sites in United States, Argentina and 11 more
- Volunteers
- 228 people
- Sponsor
- GlaxoSmithKline
Sunscreening Agent
Sun Protection Factor Assay
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02803060)
- Testing
- Coppertone (BAY987516)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Bayer
Atrial Fibrillation
RandOmised Controlled Trial of STAR Mapping™ Guided Ablation for AF.
Atrial fibrillation (AF) is the most common arrhythmia with an expected rise in prevalence over the next decade. Beyond causing troublesome symptoms AF is associated with increased mortality and morbidity.
- Trial name
- ROC-STAR (NCT04442113)
- Testing
- Pulmonary vein isolation plus ablation guided by novel STAR mapping™, Pulmonary vein isolation
- Sponsor
- Rhythm AI Ltd
Persistent, Recurrent, or Metastatic Cervical Cancer
A Study of GLS-010 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer
This is a randomized, double-blind, placebo-controlled phase III study to evaluate GLS-010 plus platinum-containing chemotherapy with or without bevacizumab as first-line treatment for persistent, recurrent, or metastatic…
- Trial name
- NCT05798819
- Testing
- GLS-010, paclitaxel, cisplatin
- Where
- China
- Volunteers
- 424 people
- Sponsor
- Guangzhou Gloria Biosciences Co., Ltd.
Advanced Parkinson's Disease
A Study to Assess the Efficacy, Safety and Tolerability of ABT-SLV187 Monotherapy in Subjects With Advanced Parkinson's Disease (PD) and Persistent Motor Complications, Despite Optimized Treatment With Available Anti-Parkinsonian Medications
The primary objective of this study is to measure the efficacy of ABT-SLV187 in subjects with advanced Parkinson's disease.
- Trial name
- NCT01960842
- Testing
- Levodopa-carbidopa intestinal gel, CADD-Legacy® 1400 ambulatory infusion pump, PEG tube
- Volunteers
- 31 people
- Sponsor
- AbbVie
Atrial Fibrillation
Optimal Timing of Dronedarone Initiation After Conversion in Patients With Persistent Atrial Fibrillation
Primary Objective: Evaluate the rate of Atrial Fibrillation (AF) recurrences one month after randomization according to different timings of initiation of dronedarone.
- Trial name
- ARTEMIS Load (NCT01140581)
- Testing
- DRONEDARONE
- Where
- 111 sites in Australia, Austria and 14 more
- Volunteers
- 402 people
- Sponsor
- Sanofi
Joint Health, Mobility
A Clinical Trial to Investigate the Efficacy and Safety of a Plant-based Cetylated Fatty Acids (CFA) on Knee Pain and Stiffness in Healthy Adults With Persistent Knee Pain
The goal of this clinical trial is to investigate the efficacy and safety of plant-derived cetylated fatty acids (CFA) on joint health and mobility in adults with persistent knee pain.
- Conditions
- Joint Health, Mobility, Knee Pain
- Trial name
- NCT07695714
- Testing
- Plant-derived cetylated fatty acids (CFA)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Everwell Health
Asthma
Efficacy, Safety and Pharmacokinetics of QAV680 in Asthma Patients
This study aims to study the efficacy (as measured by change in FEV1) and safety of two-week administration of oral QAV680 in the treatment of patients with asthma.'
- Trial name
- NCT00814216
- Testing
- QAV680, Fluticasone Propionate
- Where
- 7 sites in Germany, India
- Volunteers
- 37 people
- Sponsor
- Novartis
Sunscreening Agent
Sun Protection Factor Assay
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02823509)
- Testing
- Coppertone (BAY 987517)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Asthma
An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol (FF/VI) 200/25 Microgram (mcg) , FF/VI 100/25 mcg, and FF 100 mcg in Adults and Adolescents With Persistent Asthma.
This is a Phase III, multicenter, randomized, double-blind, stratified, parallel-group study with three active comparators in subjects with moderate to severe persistent asthma.
- Trial name
- NCT01686633
- Testing
- Fluticasone Furoate/ Vilanterol 200/25 mcg, Fluticasone Furoate/ Vilanterol 100/25 mcg, Fluticasone Furoate 100 mcg
- Where
- 136 sites in United States, Argentina and 9 more
- Volunteers
- 1,040 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Non-inferiority, Open-label, Multicenter and Randomized Clinical Trial About the Treatment of Mild to Moderate Persistent Allergic Rhinitis
To assess the efficacy of the study product Noex in the treatment of allergic rhinitis by means of the Nasal Index Score (NIS) after 4 weeks of treatment with the drug.
- Trial name
- NOEX (NCT01022047)
- Testing
- Noex, Budecort Aqua
- Where
- Brazil
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Cervical Cancer
Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of Socazolimab combined with chemotherapy with or without bevacizumab as first-Line treatment in persistent, recurrent, or metastatic cervical cancer.
- Trial name
- NCT06459687
- Testing
- Socazolimab+cisplatin/carboplatin+paclitaxel+Bevacizumab
- Where
- 5 sites in China
- Volunteers
- 440 people
- Sponsor
- Lee's Pharmaceutical Limited
Persistent Atrial Fibrillation, Atrial Arrhythmia
FIRE AND ICE II Trial Pilot
The FIRE AND ICE II Trial (Pilot) is the pilot phase of a prospective, randomized, single-blinded, multi-center, interventional post-market clinical trial, comparing efficacy and safety of isolation of the pulmonary veins (PVI)…
- Trial name
- NCT03706677
- Testing
- Cryoballoon (Arctic Front Advance Cryoballoon), Radiofrequency Catheter (ThermoCool Smarttouch)
- Where
- 5 sites in France, Germany
- Volunteers
- 69 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Asthma
A Phase II Study to Evaluate the Efficacy, Safety and Tolerability of AZD5069 in Patients With Uncontrolled Persistent Asthma.
The purpose is to Evaluate the Efficacy, Safety, and Tolerability of 3 Different Doses of AZD5069 Twice Daily as Add-on Treatment to Medium to High Dose Inhaled Corticosteroids (ICS) and Long-acting β2 Agonists (LABA), in…
- Trial name
- NIMBUS (NCT01704495)
- Testing
- AZD5069
- Where
- 96 sites in Bulgaria, Canada and 11 more
- Volunteers
- 1,147 people
- Sponsor
- AstraZeneca
Persistent Corneal Epithelial Defect
Study of DE-105 Ophthalmic Solution in Patients With Persistent Corneal Epithelial Defect
Safety and efficacy of DE-105 ophthalmic solution in patients with persistent corneal epithelial defect will be evaluated. Dose-dependent efficacy will be evaluated as well.
- Trial name
- NCT00988494
- Testing
- DE-105 ophthalmic solution
- Where
- Japan
- Volunteers
- 45 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Ovarian Cancer, Recurrent Cancer
A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma
The purpose of this study is to determine the treatment efficacy of CYH33 monotherapy in patients with recurrent or persistent ovarian, fallopian tube or primary peritoneal clear cell carcinoma harboring PIK3CA hotspot mutation…
- Trial name
- NCT05043922
- Testing
- CYH33
- Where
- 36 sites in China, Japan
- Volunteers
- 93 people
- Sponsor
- Haihe Biopharma Co., Ltd.
Asthma
Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Persistent Asthma
Approximately 480 (120 per group) would need to complete the 6 weeks of treatments.
- Trial name
- NCT03834012
- Testing
- Beclomethasone 800 µg per day, Beclomethasone 400 µg per day, Beclomethasone 640 µg per day
- Sponsor
- Adamis Pharmaceuticals Corporation
Asthma
An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol 100/25 Microgram (mcg) Inhalation Powder, Fluticasone Propionate/Salmeterol 250/50 mcg Inhalation Powder, and Fluticasone Propionate 250 mcg Inhalation Powder in Adults and Adolescents With Persistent Asthma
This study is a randomized, double-blind, double-dummy, parallel group, multicenter, non-inferiority study. The study will enroll adult and adolescent asthmatic subjects who are currently receiving mid dose inhaled…
- Trial name
- NCT02301975
- Testing
- Fluticasone Furoate/Vilanterol 100/25 mcg via ELLIPTA inhaler, Fluticasone Propionate/Salmeterol 250/50 mcg via ACCUHALER/DISKUS inhaler, Fluticasone Propionate 250 mcg via ACCUHALER/DISKUS inhaler
- Where
- 179 sites in United States, Argentina and 10 more
- Volunteers
- 1,526 people
- Sponsor
- GlaxoSmithKline