Clinical trials: Persistent Asthma
Asthma
A Serious Asthma Outcome Study With Mometasone Furoate/Formoterol Versus Mometasone Furoate in Asthmatics 12 Years and Over (P06241)
The purpose of this study is to test the safety of DULERA. DULERA is a pressurized metered-dose inhaler (MDI) that contains two drugs combined, namely mometasone and formoterol in a single inhaler.
- Trial name
- SPIRO (NCT01471340)
- Testing
- Mometasone Furoate/Formoterol MDI 100/5 mcg, Mometasone Furoate/Formoterol MDI 200/5 mcg, Mometasone Furoate MDI 100 mcg
- Volunteers
- 11,744 people
- Sponsor
- Organon and Co
Mild Persistent Asthma, Uncomplicated
Efficacy and Safety of Beta-adrenoceptor Inverse Agonist, Nadolol, in Mild Asthma
The purpose of this study is to test the hypothesis that 18-22 week treatment with the inverse agonist nadolol will improve airway hyperresponsiveness in patients with mild asthma, compared to placebo.
- Trial name
- NCT01804218
- Testing
- Nadolol
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Invion, Inc.
Asthma
Asthma Control Among Patients Receiving Inhaled Corticosteroids in Thailand
The purpose of this study is to determine the percentage of patients who has reached the GINA guideline of asthma treatment after receiving any inhaled corticosteroid for 3 months or longer in actual clinical practice.
- Trial name
- NCT00800904
- Where
- 26 sites in Thailand
- Volunteers
- 1,210 people
- Sponsor
- AstraZeneca
Asthma
Study of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder Inhaler
This study is to evaluate the safety and efficacy of fluticasone propionate and fluticasone propionate salmeterol in pediatric participants with a documented history of persistent asthma.
- Trial name
- NCT02980133
- Testing
- Fluticasone Propionate, Fluticasone Propionate/Salmeterol
- Where
- 118 sites in United States, Georgia and 3 more
- Volunteers
- 841 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
Study of Mometasone Furoate/Formoterol Combination and Fluticasone/Salmeterol in Persistent Asthmatics Previously Treated With Inhaled Glucocorticosteroids (P04139)
The purpose of this study is to evaluate the long-term safety of mometasone furoate/formoterol (MF/F) metered dose inhaler (MDI) 200/10 mcg twice-a-day (BID) and MF/F MDI 400/10 mcg BID and two doses of fluticasone/salmeterol…
- Trial name
- NCT00379288
- Testing
- mometasone furoate combination MDI 200/10 mcg BID, mometasone furoate combination MDI 400/10 mcg BID, Fluticasone/Salmeterol 250/50 mcg BID
- Volunteers
- 404 people
- Sponsor
- Organon and Co
Asthma
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Persistent Asthma.
This study is designed to determine if the investigational drug is effective and safe in individuals with asthma.
- Trial name
- NCT00398645
- Testing
- GW685698X 200mcg,GW685698X 200mcg and 400mcg
- Where
- 82 sites in United States, Australia and 14 more
- Volunteers
- 648 people
- Sponsor
- GlaxoSmithKline
Asthma
SOLO-Symbicort® in the Treatment of Persistent Asthma in Adolescents & Adults
The purpose of this study is to compare Symbicort Single Inhaler treatment with the Best Conventional Practice in patients with persistent asthma
- Trial name
- NCT00238784
- Testing
- Budesonide/formoterol Turbuhaler
- Where
- 3 sites in Canada
- Volunteers
- 1,300 people
- Sponsor
- AstraZeneca
Moderate Persistent Asthma
The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children With Moderate Persistent Asthma
The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children with Moderate Persistent Asthma
- Trial name
- NCT05632549
- Testing
- L-Carnitine 500Mg Oral Tablet, Biotin Capsules
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Asthma
Single Dose Study to Assess Efficacy, Safety and Tolerability of LAS100977 in Asthmatic Patients.
The purpose of this study is to evaluate the pharmacodynamics of single doses of inhaled LAS100977 QD in patients with persistent asthma.
- Trial name
- NCT01425801
- Testing
- LAS100977 0.313 μg, LAS100977 0.625 μg, LAS100977 1.25 μg
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 62 people
- Sponsor
- AstraZeneca
Asthma
Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Persistent Asthma
Approximately 480 (120 per group) would need to complete the 6 weeks of treatments.
- Trial name
- NCT03834012
- Testing
- Beclomethasone 800 µg per day, Beclomethasone 400 µg per day, Beclomethasone 640 µg per day
- Sponsor
- Adamis Pharmaceuticals Corporation
Asthma
Efficacy and Safety of Single Doses of Indacaterol Delivered Via a Single Dose Dry Powder Inhaler (SDDPI) Compared to Placebo in Patients With Persistent Asthma
The study is designed to obtain safety and efficacy data on three dose levels of indacaterol when delivered via an SDDPI in patients with persistent asthma.
- Trial name
- NCT00403637
- Testing
- indacaterol maleate
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- Novartis
Asthma
A Double Blind Open Label Comparator Study to Compare Treatments in 4 to 11 Year Old Patients With Asthma
The purpose of the study is to characterize the pharmacokinetic profiles of fluticasone propionate and/or salmeterol when delivered as a single oral inhalation dose of Fp MDPI and FS MDPI.
- Trial name
- NCT02680561
- Testing
- Fluticasone Propionate MDPI, Fluticasone Propionate/Salmeterol MDPI, Fluticasone propionate/salmeterol
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
Specific Use-Result of Spiriva Respimat® in Asthmatics
The study objective is to investigate the safety and effectiveness of Spiriva Respimat in patients with mild to moderate persistent asthma under real-world use
- Trial name
- NCT03188120
- Testing
- Spiriva Respimat
- Where
- Japan
- Volunteers
- 193 people
- Sponsor
- Boehringer Ingelheim