Clinical trials: Persistent Ductus Arteriosus
Persistent Ductus Arteriosus, Complication of Prematurity
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants.
- Conditions
- Persistent Ductus Arteriosus, Complication of Prematurity, Pain or Discomfort in Intensive Care of Preterm Infants
- Trial name
- PreParaS (NCT01938261)
- Testing
- paracetamol, 0.45 % saline solution
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Persistent Ductus Arteriosus
Betamethasone and Closure of Ductus Arteriosus
The ductus arteriosus (DA) normally closes after birth as a result of exposure to oxygen. Its persistence of DA (PDA) occurs in 20 to 50% of very preterm infants and is associated with significant morbidity and mortality…
- Trial name
- CELESTE (NCT05987202)
- Testing
- DA closure in a population of premature infants
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Pre-Term, Persistent Ductus Arteriosus
Evaluation of the Brain and Renal Regional Oxygenation Using NIRS in Preterm Infants
This study evaluates the brain and renal oxygenation using near infrared spectroscopy in preterm infants with persistent ductus arteriosus
- Trial name
- NCT04295395
- Testing
- NONIN SenSmart model X-100 near- infrared spectrometer
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Vilnius University
Persistent Ductus Arteriosus
Clinical Trial to Evaluate Two Guidelines for the Administration of Ibuprofen in the Treatment of Persistent Ductus Arteriosus Eco-guided: Impact in the Intestinal Prognosis
Persistent ductus arteriosus (DA) is a common entity in the premature newborn and is associated with high morbidity and mortality. There is still controversy about which is the best treatment for its closure.
- Trial name
- IBU24h-EchoG (NCT04282941)
- Testing
- Ibuprofen in continuous (24 hours) iv infusion and EchoG, IV bolus Ibuprofen slow (15 minutes) and EchoG
- Where
- 3 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Patent Ductus Arteriosus, Persistent Pulmonary Hypertension of the Newborn
Plethismographic Perfusion Index in Neonates
Photoplethismography will be measured and compared in newborns suffering from patent ductus arteriosus and normal controls.
- Trial name
- NCT02380040
- Testing
- PPG
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Persistent Ductus Arteriosus
The Best Treatment Strategy: Surgical vs Pharmacological to Close the Ductus Arteriosus Persistent in Preterm Infants
The decision to treat patent ductus arteriosus in preterm infants, varies from a conservative, medical or immediate surgical treatment; although, at present, there is some controversy about this decision.
- Trial name
- NCT02602054
- Testing
- Surgical treatment, Control group
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval