Clinical trials: Persistent Pain
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Persistent Idiopathic Facial Pain (PIFP)
Deciphering Persistent Orofacial Pain - PIFP
Persistent non-dental orofacial pain is common yet poorly characterised, and its pathophysiology remains largely unknown. Two clinically similar entities are distinguished: post-traumatic trigeminal neuropathic pain (PTNP), in…
- Trial name
- NCT07791004
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Chronic Pain, Persistent Pain
Physiotherapy Intervention Program for Chronic Pain Associated With Depressive Disorder
This prospective longitudinal pre-post intervention study aims to evaluate the effects of an 8-week physiotherapy program combining face-to-face and asynchronous tele-rehabilitation sessions in individuals with chronic persistent…
- Conditions
- Chronic Pain, Persistent Pain, Depressive Disorder
- Trial name
- NCT07764848
- Testing
- Hybrid Physiotherapy Program
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Persistent Post Operative Opioid Use, Post-surgical Pain
Personalized Post-Operative Pain Management
The main questions this study aims to answer are: Does perioperative PGx personalized opiate therapy reduce persistent post-operative opioid use dependency, improve pain management and reduce opiate related adverse events in…
- Trial name
- NCT06669650
- Testing
- PGx guided personalized post-operative pain management, Oxycodone, Hydromorphone
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Hydromorphone Use, Acute Postoperative Pain
Methadone and Hydromorphone For Spinal Surgery
Patients undergoing major spinal surgery continue to experience moderate-to-severe pain during the first 2-3 days following the operative procedure.
- Conditions
- Hydromorphone Use, Acute Postoperative Pain, Patient Satisfaction, Chronic Persistent Surgical Pain
- Trial name
- NCT02107339
- Testing
- Methadone, Hydromorphone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Persistent/Chronic Low Back Pain
A Retrospective Study to Identify New "Omics" Biomarkers of Chronic/Persistent Low Back Pain
Low back pain (LBP) is one of the most common medical problems encountered in daily life; it is related to disability and work absence and accounts for high economical costs in Western societies.
- Trial name
- NCT02037789
- Where
- 6 sites in United States, Australia and 3 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Parma
Persistent Postherniotomy Pain
Pain After Deep Electrical Stimulation in the Groin in Pain Free Subjects
Sensory disturbances in persistent postherniotomy pain, include hyperalgesia from deeper structures as well as the skin. Whether this is one combined pain syndrome, where for instance deep pain leads to cutaneous hyperalgesia, or…
- Trial name
- HADES-1 (NCT01701427)
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Root Canal Therapy, Persistent Tooth Pain
DPBRN Persistent Pain and Root Canal Therapy
The purpose of this study is to document by survey the occurence of tooth pain present 3 months and 6 months after root canal therapy in the patients recruited for the DPBRN "Peri-operative tooth pain" study.
- Trial name
- NCT01201668
- Where
- 8 sites in United States, Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network