Clinical trials: Personality
Borderline Personality Disorder, PTSD
Neural Correlates of Stress Hormones
To investigate which neuronal correlates underlie cortisol-induced enhancement of memory retrieval in PTSD and BPD.
- Trial name
- Cort-fMRI (NCT02523664)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Emotions, Facial Emotion Recognition
Improving Emotion Recognition Ability to Support Social Development in Children: A Quasi-Experimental Study
The goal of this quasi-experimental study is to investigate whether enhancing emotion recognition abilities can improve social behavior in primary school children.
- Conditions
- Emotions, Facial Emotion Recognition, Antisocial Behavior, Nonverbal Communication
- Trial name
- I4C (NCT07097090)
- Testing
- Emotion Recognition Training Program: A structured school-based intervention designed to enhance children's ability to recognize emotions through facial expressions, tone of voice, and body language., No Intervention: Observational Cohort
- Where
- Italy
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
The goal of PROSPER-B is to study effectiveness of EMDR compared to integrated DBT-EMDR in treatment-seeking, adult patients with comorbid PTSD and Borderline Personality Disorder (BPD).
- Trial name
- PROSPER-B (NCT03833453)
- Testing
- EMDR, DBT
- Where
- Netherlands
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Arkin
Alzheimer Disease, Semantic Dementia
Memory and Social Interactions
Memory and social interaction are intimately linked. On the one hand, social interaction is a privileged context for learning, and on the other hand, appropriate social interactions involve remembering the partners encountered…
- Trial name
- MEM&SO (NCT05800028)
- Testing
- Learning new information
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Schizophrenia
Familial Schizophrenia and Spectrum Personality Disorders
We propose to recruit 150 case families (i.e., families with a schizophrenia proband), 150 control families, and 45 control subjects who exhibit schizophrenia spectrum personality symptoms in the absence of a family history of…
- Trial name
- NCT00666146
- Where
- 3 sites in United States
- Volunteers
- 539 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Impulse Control Disorders, Borderline Personality Disorder
fMRI in Impulsivity
This study aims to use resting-state and task based functional Magnetic Resonance Imaging (fMRI) as a tool to evaluate trait characteristics of impulsivity in subjects with borderline personality disorder.
- Trial name
- NCT02755181
- Testing
- Experimental
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Personality
Personality Bleaching
128 patients between 18 and 76 years who attended the Operative Dentistry Clinic at Dental School, Universidad de Chile, were included in the study.
- Trial name
- NEOFFI (NCT02330614)
- Testing
- Bleaching by peroxide carbamide 10%, Nothing - control group
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Chile
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago
Enduring Personality Change
Effects of High-energy Nutritional Protein-based Bar on the Performance of Young Athletes
A study will be conducted in Lahore. Non probability convenience sampling technique will be applied on patients who will be allocated through computerized randomization into group A \& group B to collect data.
- Trial name
- NCT07065513
- Testing
- Normal diet, Normal diet plus nutritional protein-based bar
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Diagnosis, Dual (Psychiatry)
Efficacy of Animal-assisted Therapy in Patients With Borderline Personality Disorder and Addictions.
Animal-assisted therapy (AAT) is a complementary intervention of therapy that has shown positive results in the treatment of various pathologies.
- Trial name
- NCT05115266
- Testing
- Animal-assisted therapy (AAT, Usual treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Miguel Monfort Montolio
Traumatic Brain Injury, Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive…
- Conditions
- Traumatic Brain Injury, Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT04296604
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Aggression, Risk-Taking
Transcranial Direct Current Stimulation in Offenders
This study investigates the effect of upregulating prefrontal cortex activity on risk-taking, and antisocial and aggressive behavior in violent offenders.
- Conditions
- Aggression, Risk-Taking, Antisocial Behavior
- Trial name
- NCT03036683
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Olivia Choy
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Psycho-social Support on Mental Health and Hope of Adolescents Affected by Earthquake in Nepal
Adolescents are prone to mental health problems such as post-traumatic stress disorder (PTSD) and depression which could become worse in the aftermath of disasters.
- Trial name
- NCT03387007
- Testing
- Psychosocial support training for school teachers
- Volunteers
- 1,912 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder
This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction…
- Conditions
- Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD)
- Trial name
- TLUR (NCT07337889)
- Testing
- Relationship-use questionnaire
- Where
- France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Neural Systems, Psychopathology
Psychological Mechanisms of Behavioral Dysregulation
This study is directed toward a better understanding of how the brain regulates emotions and social and antisocial behavior. It will look at the use of the orbital frontal cortex and amygdala of the brain.
- Trial name
- NCT00352456
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Social Rejection, Attachement Style
Does Attachment Anxiety Moderate the Influence of Social Rejection on Alcohol Use Among Young Adults?
Research shows that heavy drinking patterns are linked to many harmful consequences including death, sexual assault, risky sexual behavior, and drug use.
- Trial name
- PSDCP-2 (NCT07905430)
- Testing
- Social Rejection Feedback, Social Acceptance
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Wilmington
Borderline Personality Disorder
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
The study will examine behavioral patterns and underlying neural correlates which distinguish patients with borderline personality disorder (BPD) from healthy subjects as they participate in a two-person trust game and will…
- Trial name
- NCT02225600
- Testing
- 40 IU Intranasal Oxytocin, 24 IU intranasal Oxytocin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai